

Professional Summary
Education & Certifications
- Medical Education: Dartmouth Geisel School of Medicine (1987) NH
- Fellowship: Mclean Hospital (1992) MA
- Residency: Mclean Hospital (1991) MA
-
- Board Certification: American Board of Psychiatry and Neurology, Psychiatry (1992)
- Fellowship, Harvard Medical School, Neuroscience (1992)
- Fellowship, Harvard Medical School, Psychiatry (1992)
- M.D., Dartmouth, Medicine (1987)
- Fellowship, Stanford University, Neuroscience (1983)
- Ph.D., UCLA, Anatomy and Physiology (1980)
Honors & Awards
- Councilor, Board of Councilors, International Society for Bipolar Disorders (ISBD) (2009-2011)
- Elected as a member, American College of Psychiatrists (2013)
- Elected Board Member, American Society of Clinical Psychopharmacology (2017-2025)
-
- Elected by peers for inclusion, Best Doctors in America® (1996-2010)
- Elected to Fellow, American College of Neuropsychopharmacology (ACNP) (2009)
- Elected Treasurer, American Society of Clinical Psychopharmacology (2019)
- Gerald L. Klerman Senior Investigator Award, Depression and Bipolar Support Alliance (2008)
Administrative Appointments
- Chair for Veterans Affairs, Department of Defense and VA Bipolar Disorder Treatment Guidelines (2008 - 2012)
- Chair, Subcommittee on Bipolar Disorders for APA Workgroup on Mood Disorders, American Psychiatric Association Diagnostic and Statistical Manual for Mental Disorders 5 (DSM-5) (2007 - 2012)
- Director, Bipolar and Depression Research Program, VA Palo Alto Health Care System, Palo Alto, CA (2008 - 2018)
-
- Director, Cooperative Studies Program (CSP) Network of Dedicated Enrollment Sites (NODES), VA Palo Alto (2012 - Present)
- Director, Exploratory Therapeutics Laboratory (2018 - Present)
- Member, Editorial Board Bipolar Disorders - An International Journal of Psychiatry and Neurosciences (2000 - Present)
- Member, Editorial Board, International Journal of Bipolar Disorders (2009 - Present)
- Member, Appointment and Promotions, Department of Psychiatry and Behavioral Sciences (2010 - Present)
- Member, Research and Development Committee, VA Palo Alto Health Care System (2011 - Present)
- Member, Editorial Board Depression and Anxiety (2012 - Present)
- Member, Workgroup for Mood Disorders, American Psychiatric Association Diagnostic and Statistical Manual for Mental Disorders 5 (DSM5) (2007 - 2012)
- President, International Society of Bipolar Disorders*** (2018 - 2020)
- Treasurer and Secretary, International Society of Bipolar Disorders **** (2014 - 2018)
Publications
-
Mental health care from the public perspective: The Texas Medication Algorithm Project
Shon, S. P., Crismon, M. L., Toprac, M. G., Trivedi, M., Miller, A. L., Suppes, T., & Rush, A. J. (1999). Mental health care from the public perspective: The Texas Medication Algorithm Project. Presented at the Symposium on Pharmacoeconomic Factors Related to the Treatment of Schizophrenia, CHICAGO,ILLINOIS: PHYSICIANS POSTGRADUATE PRESS. -
Treatment of corticosteroid-induced mood changes with olanzapine
Brown, E. S., Khan, D. A., & Suppes, T. (1999). Treatment of corticosteroid-induced mood changes with olanzapine. AMERICAN JOURNAL OF PSYCHIATRY, 156(6), 968–968. -
Medication treatment for the severely and persistently mentally ill: The Texas Medication Algorithm Project
Rush, A. J., Rago, W. V., Crismon, M. L., Toprac, M. G., Shon, S. P., Suppes, T., … Altshuler, K. Z. (1999). Medication treatment for the severely and persistently mentally ill: The Texas Medication Algorithm Project. JOURNAL OF CLINICAL PSYCHIATRY, 60(5), 284–291. -
-
Lamotrigine for the treatment of bipolar disorder: a clinical case series
Suppes, T., Brown, E. S., McElroy, S. L., Keck, P. E., Nolen, W., Kupka, R., … Post, R. M. (1999). Lamotrigine for the treatment of bipolar disorder: a clinical case series. JOURNAL OF AFFECTIVE DISORDERS, 53(1), 95–98. -
Clinical outcome in a randomized 1-year trial of clozapine versus treatment as usual for patients with treatment-resistant illness and a history of mania
Suppes, T., Webb, A., Paul, B., Carmody, T., Kraemer, H., & Rush, A. J. (1999). Clinical outcome in a randomized 1-year trial of clozapine versus treatment as usual for patients with treatment-resistant illness and a history of mania. AMERICAN JOURNAL OF PSYCHIATRY, 156(8), 1164–1169. -
Lamotrigine in the treatment of bipolar depression
Bowden, C. L., Mitchell, P., & Suppes, T. (1999). Lamotrigine in the treatment of bipolar depression. Presented at the 11th European-College-of-Neuropsychopharmacology Congress, PARIS,FRANCE: ELSEVIER SCIENCE BV. -
Treating bipolar illness: Focus on treatment algorithms and management of the sleep-wake cycle
Leibenluft, E., & Suppes, T. (1999). Treating bipolar illness: Focus on treatment algorithms and management of the sleep-wake cycle. AMERICAN JOURNAL OF PSYCHIATRY, 156(12), 1976–1981. -
Forum. What are the mental health complications of steroid therapy?
Brown, E. S., & Suppes, T. (2000). Forum. What are the mental health complications of steroid therapy? The Harvard Mental Health Letter, 16(8), 8-? -
Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features
Tohen, M., Hennen, J., Zarate, C. M., BALDESSARINI, R. J., Strakowski, S. M., Stoll, A. L., … Cohen, B. M. (2000). Two-year syndromal and functional recovery in 219 cases of first-episode major affective disorder with psychotic features. AMERICAN JOURNAL OF PSYCHIATRY, 157(2), 220–228. -
Switching outpatients between atypical antipsychotics
Bogan, A. M., Shellhorn, E., Brown, E. S., Mcdanald, C., & Suppes, T. (2000). Switching outpatients between atypical antipsychotics. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 24(2), 351–355. -
The longitudinal course of bipolar disorder
Suppes, T., Dennehy, E. B., & Gibbons, E. W. (2000). The longitudinal course of bipolar disorder. JOURNAL OF CLINICAL PSYCHIATRY, 61, 23–30. -
Effect size of lithium, divalproex sodium, and carbamazepine in children and adolescents with bipolar disorder
Kowatch, R. A., Suppes, T., Carmody, T. J., Bucci, J. P., Hume, J. H., Kromelis, M., … Rush, A. J. (2000). Effect size of lithium, divalproex sodium, and carbamazepine in children and adolescents with bipolar disorder. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 39(6), 713–720. -
Open-label adjunctive topiramate in the treatment of bipolar disorders
McElroy, S. L., Suppes, T., Keck, P. E., Frye, M. A., Denicoff, K. D., Altshuler, L. L., … Post, R. M. (2000). Open-label adjunctive topiramate in the treatment of bipolar disorders. BIOLOGICAL PSYCHIATRY, 47(12), 1025–1033. -
Comparison of the Internal State Scale to clinician-administered scales in asthma patients receiving corticosteroid therapy
Brown, E. S., Bauer, M. S., Suppes, T., Khan, D. A., & Carmody, T. (2000). Comparison of the Internal State Scale to clinician-administered scales in asthma patients receiving corticosteroid therapy. GENERAL HOSPITAL PSYCHIATRY, 22(3), 180–183. -
Gabapentin for treatment of bipolar and schizoaffective disorders
Bennett, J., GOLDMAN, W. T., & Suppes, T. (1997). Gabapentin for treatment of bipolar and schizoaffective disorders. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 17(2), 141–142. -
Efficacy of divalproex therapy for schizoaffective disorder
Bogan, A. M., Brown, E. S., & Suppes, T. (2000). Efficacy of divalproex therapy for schizoaffective disorder. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 20(5), 520–522. -
The McLean-Harvard first-episode project: 6-month symptomatic and functional outcome in affective and noneffective psychosis
Tohen, M., Strakowski, S. M., Zarate, C., Hennen, J., Stoll, A. L., Suppes, T., … BALDESSARINI, R. J. (2000). The McLean-Harvard first-episode project: 6-month symptomatic and functional outcome in affective and noneffective psychosis. BIOLOGICAL PSYCHIATRY, 48(6), 467–476. -
Methodological issues in developing new acute treatments for patients with bipolar illness
Rush, A. J., Post, R. M., Nolen, W. A., Keck, P. E., Suppes, T., Altshuler, L., & McElroy, S. L. (2000). Methodological issues in developing new acute treatments for patients with bipolar illness. BIOLOGICAL PSYCHIATRY, 48(6), 615–624. -
Validation of the prospective NIMH-Life-Chart Method (NIMH-LCM (TM)-p) for longitudinal assessment of bipolar illness
Denicoff, K. D., Leverich, G. S., Nolen, W. A., Rush, A. J., McElroy, S. L., Keck, P. E., … Post, R. M. (2000). Validation of the prospective NIMH-Life-Chart Method (NIMH-LCM (TM)-p) for longitudinal assessment of bipolar illness. PSYCHOLOGICAL MEDICINE, 30(6), 1391–1397. -
A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder
Calabrese, J. R., Suppes, T., Bowden, C. L., Sachs, G. S., Swann, A. C., McElroy, S. L., … Monaghan, E. T. (2000). A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. JOURNAL OF CLINICAL PSYCHIATRY, 61(11), 841–850. -
A review of randomized, controlled clinical trials in acute mania
Keck, P. E., Mendlwicz, J., Calabrese, J. R., Fawcett, J., Suppes, T., Vestergaard, P. A., & Carbonell, C. (2000). A review of randomized, controlled clinical trials in acute mania. Presented at the 1st International Exchange on Bipolar Disorders Meeting (IEBD), BARCELONA,SPAIN: ELSEVIER SCIENCE BV. -
Psychopharmacologic treatment strategies for depression, bipolar disorder, and schizophrenia
Glick, I. D., Suppes, T., Debattista, C., Hu, R. J., & Marder, S. (2001). Psychopharmacologic treatment strategies for depression, bipolar disorder, and schizophrenia. ANNALS OF INTERNAL MEDICINE, 134(1), 47–60. -
Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder
McElroy, S. L., Altshuler, L. L., Suppes, T., Keck, P. E., Frye, M. A., Denicoff, K. D., … Post, R. M. (2001). Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. AMERICAN JOURNAL OF PSYCHIATRY, 158(3), 420–426. -
Clozapine associated with decreased suicidality in bipolar disorder: a case report.
Vangala, V. R., Brown, E. S., & Suppes, T. (1999). Clozapine associated with decreased suicidality in bipolar disorder: a case report. Bipolar Disorders, 1(2), 123–124. -
Gabapentin in the acute treatment of refractory bipolar disorder.
Altshuler, L. L., Keck, P. E., McElroy, S. L., Suppes, T., Brown, E. S., Denicoff, K., … Post, R. (1999). Gabapentin in the acute treatment of refractory bipolar disorder. Bipolar Disorders, 1(1), 61–65. -
Drug abuse and bipolar disorder: comorbidity or misdiagnosis?
Brown, E. S., Suppes, T., Adinoff, B., & Thomas, N. R. (2001). Drug abuse and bipolar disorder: comorbidity or misdiagnosis? JOURNAL OF AFFECTIVE DISORDERS, 65(2), 105–115. -
The Stanley Foundation Bipolar Network. I. Rationale and methods.
Post, R. M., Nolen, W. A., Kupka, R. W., Denicoff, K. D., Leverich, G. S., Keck, P. E., … Walden, J. (2001). The Stanley Foundation Bipolar Network. I. Rationale and methods. The British Journal of Psychiatry. Supplement, 41, s169–76. -
The Stanley Foundation Bipolar Network. 2. Preliminary summary of demographics, course of illness and response to novel treatments.
Kupka, R. W., Nolen, W. A., Altshuler, L. L., Denicoff, K. D., Frye, M. A., Leverich, G. S., … Post, R. M. (2001). The Stanley Foundation Bipolar Network. 2. Preliminary summary of demographics, course of illness and response to novel treatments. The British Journal of Psychiatry. Supplement, 41, s177–83. -
Texas Medication Algorithm Project: Development and feasibility testing of a treatment algorithm for patients with bipolar disorder
Suppes, T., Swann, A. C., Dennehy, E. B., Habermacher, E. D., Mason, M., Crismon, M. L., … Altshuler, K. Z. (2001). Texas Medication Algorithm Project: Development and feasibility testing of a treatment algorithm for patients with bipolar disorder. JOURNAL OF CLINICAL PSYCHIATRY, 62(6), 439–447. -
Bipolar rapid cycling: Focus on depression as its hallmark
Calabrese, J. R., Shelton, M. D., Bowden, C. L., Rapport, D. J., Suppes, T., Shirley, E. R., … Caban, S. J. (2001). Bipolar rapid cycling: Focus on depression as its hallmark. Presented at the Symposium on the Role of Anticonvulsants as Mood Stabilizers, SSAN ANTONIO,TEXAS: PHYSICIANS POSTGRADUATE PRESS. -
Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy
Tohen, M., Chengappa, K. N. R., Suppes, T., Zarate, C. A., Calabrese, J. R., Bowden, C. L., … Breier, A. (2002). Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy. ARCHIVES OF GENERAL PSYCHIATRY, 59(1), 62–69. -
Mood changes during prednisone bursts in outpatients with asthma
Brown, E. S., Suppes, T., Khan, D. A., & Carmody, T. J. (2002). Mood changes during prednisone bursts in outpatients with asthma. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 22(1), 55–61. -
Lithium Withdrawal in Bipolar Disorder: Implications for Clinical Practice and Experimental Therapeutics Research.
Baldessarini, R. J., Suppes, T., & Tondo, L. (1996). Lithium Withdrawal in Bipolar Disorder: Implications for Clinical Practice and Experimental Therapeutics Research. American Journal of Therapeutics, 3(7), 492–496. -
The Stanley Foundation Bipolar Treatment Outcome Network I. Longitudinal methodology
Leverich, G. S., Nolen, W. A., Rush, A. J., McElroy, S. L., Keck, P. E., Denicoff, K. D., … Post, R. M. (2001). The Stanley Foundation Bipolar Treatment Outcome Network I. Longitudinal methodology. JOURNAL OF AFFECTIVE DISORDERS, 67(1-3), 33–44. -
The Stanley Foundation Bipolar Treatment Outcome Network II. Demographics and illness characteristics of the first 261 patients
Suppes, T., Leverich, G. S., Keck, P. E., Nolen, W. A., Denicoff, K. D., Altshuler, L. L., … Post, R. M. (2001). The Stanley Foundation Bipolar Treatment Outcome Network II. Demographics and illness characteristics of the first 261 patients. JOURNAL OF AFFECTIVE DISORDERS, 67(1-3), 45–59. -
Rate of switch in bipolar patients prospectively treated with second-generation antidepressants as augmentation to mood stabilizers
Post, R. M., Altshuler, L. L., Frye, M. A., Suppes, T., Rush, A. J., Keck, P. E., … Nolen, W. A. (2001). Rate of switch in bipolar patients prospectively treated with second-generation antidepressants as augmentation to mood stabilizers. BIPOLAR DISORDERS, 3(5), 259–265. -
Correlates of overweight and obesity in 644 patients with bipolar disorder
McElroy, S. L., Frye, M. A., Suppes, T., Dhavale, D., Keck, P. E., Leverich, G. S., … Post, R. M. (2002). Correlates of overweight and obesity in 644 patients with bipolar disorder. JOURNAL OF CLINICAL PSYCHIATRY, 63(3), 207–213. -
Combined Clozapine and Electroconvulsive Therapy.
Frankenburg, F. R., Suppes, T., & McLean, P. E. (1993). Combined Clozapine and Electroconvulsive Therapy. Convulsive Therapy, 9(3), 176–180. -
Early physical and sexual abuse associated with an adverse course of bipolar illness
Leverich, G. S., McElroy, S. L., Suppes, T., Keck, P. E., Denicoff, K. D., Nolen, W. A., … Post, R. M. (2002). Early physical and sexual abuse associated with an adverse course of bipolar illness. BIOLOGICAL PSYCHIATRY, 51(4), 288–297. -
High rate of autoimmune thyroiditis in bipolar disorder: Lack of association with lithium exposure
Kupka, R. W., Nolen, W. A., Post, R. M., McElroy, S. L., Altshuler, L. L., Denicoff, K. D., … Drexhage, H. A. (2002). High rate of autoimmune thyroiditis in bipolar disorder: Lack of association with lithium exposure. BIOLOGICAL PSYCHIATRY, 51(4), 305–311. -
Report of the Texas Consensus Conference Panel on Medication Treatment of Bipolar Disorder 2000
Suppes, T., Dennehy, E. B., Swann, A. C., Bowden, C. L., Calabrese, J. R., Hirschfeld, R. M. A., … Shon, S. R. (2002). Report of the Texas Consensus Conference Panel on Medication Treatment of Bipolar Disorder 2000. JOURNAL OF CLINICAL PSYCHIATRY, 63(4), 288–299. -
Olanzapine versus divalproex in the treatment of acute mania
Tohen, M., Baker, R. W., Altshuler, L. L., Zarate, C. A., Suppes, T., Ketter, T. A., … Tollefson, G. A. (2002). Olanzapine versus divalproex in the treatment of acute mania. AMERICAN JOURNAL OF PSYCHIATRY, 159(6), 1011–17. -
Assessment of beliefs in the effectiveness of acupuncture for treatment of psychiatric symptoms
Dennehy, E. B., Webb, A., & Suppes, T. (2002). Assessment of beliefs in the effectiveness of acupuncture for treatment of psychiatric symptoms. JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 8(4), 421–425. -
Developing novel treatments for mood disorders: Accelerating discovery
Tamminga, C. A., Nemeroff, C. B., Blakely, R. D., Brady, L., Carter, C. S., Davis, K. L., … Suppes, T. (2002). Developing novel treatments for mood disorders: Accelerating discovery. BIOLOGICAL PSYCHIATRY, 52(6), 589–609. -
Evidence-based long-term treatment of bipolar II disorder
Suppes, T., & Dennehy, E. B. (2002). Evidence-based long-term treatment of bipolar II disorder. Presented at the Symposium on Long-Term Use of Mood Stabilizers in Bipolar Disorder, SAN ANTONIO,TX: PHYSICIANS POSTGRADUATE PRESS. -
Rash in multicenter trials of lamotrigine in mood disorders: Clinical relevance and management
Calabrese, J. R., Sullivan, J. R., Bowden, C. L., Suppes, T., Goldberg, J. F., Sachs, G. S., … Kusumakar, V. (2002). Rash in multicenter trials of lamotrigine in mood disorders: Clinical relevance and management. JOURNAL OF CLINICAL PSYCHIATRY, 63(11), 1012–1019. -
Review of the use of topiramate for treatment of bipolar disorders
Suppes, T. (2002). Review of the use of topiramate for treatment of bipolar disorders. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 22(6), 599–609. -
Tiagabine in treatment refractory bipolar disorder: a clinical case series
Suppes, T., Chisholm, K. A., Dhavale, D., Frye, M. A., Atshuler, L. L., McElroy, S. L., … Post, R. M. (2002). Tiagabine in treatment refractory bipolar disorder: a clinical case series. BIPOLAR DISORDERS, 4(5), 283–289. -
High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder
Breunis, M. N., Kupka, R. W., Nolen, W. A., Suppes, T., Denicoff, K. D., Leverich, G. S., … Drexhage, H. A. (2003). High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder. BIOLOGICAL PSYCHIATRY, 53(2), 157–165. -
Clinician ratings vs. global ratings of symptom severity: a comparison of symptom measures in the bipolar disorder module, phase II, Texas Medication Algorithm Project
Brown, E. S., Rush, A. J., Biggs, M. M., Shores-Wilson, K., Carmody, T. J., & Suppes, T. (2003). Clinician ratings vs. global ratings of symptom severity: a comparison of symptom measures in the bipolar disorder module, phase II, Texas Medication Algorithm Project. PSYCHIATRY RESEARCH, 117(2), 167–175. -
Catching up on health outcomes: The Texas Medication Algorithm Project
Kashner, T. M., Carmody, T. J., Suppes, T., Rush, A. J., Crismon, M. L., Miller, A. L., … Trivedi, M. (2003). Catching up on health outcomes: The Texas Medication Algorithm Project. HEALTH SERVICES RESEARCH, 38(1), 311–331. -
The efficacy of olanzapine monotherapy for acute hypomania or mania in an outpatient setting
Dennehy, E. B., Doyle, K., & Suppes, T. (2003). The efficacy of olanzapine monotherapy for acute hypomania or mania in an outpatient setting. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 18(3), 143–145. -
Texas Medication Algorithm Project, Phase 3 (TMAP-3): Rationale and study design
Rush, A. J., Crismon, M. L., Kashner, T. M., Toprac, M. G., Carmody, T. J., Trivedi, M. H., … Altshuler, K. Z. (2003). Texas Medication Algorithm Project, Phase 3 (TMAP-3): Rationale and study design. JOURNAL OF CLINICAL PSYCHIATRY, 64(4), 357–369. -
Texas Medication Algorithm Project, Phase 3 (TMAP-3): Clinical results for patients with a history of mania
Suppes, T., Rush, A. J., Dennehy, E. B., Crismon, M. L., Kashner, T. M., Toprac, M. G., … Shon, S. P. (2003). Texas Medication Algorithm Project, Phase 3 (TMAP-3): Clinical results for patients with a history of mania. JOURNAL OF CLINICAL PSYCHIATRY, 64(4), 370–382. -
Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder
Frye, M. A., Altshuler, L. L., McElroy, S. L., Suppes, T., Keck, P. E., Denicoff, K., … Post, R. M. (2003). Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder. AMERICAN JOURNAL OF PSYCHIATRY, 160(5), 883–889. -
Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network
Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T., Keck, P. E., McElroy, S. L., … Post, R. M. (2003). Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network. JOURNAL OF CLINICAL PSYCHIATRY, 64(5), 506–515. -
How rare is bipolar disorder not otherwise specified?
Ozcan, M. E., Shiekh, M., & Suppes, T. (2003). How rare is bipolar disorder not otherwise specified? BIPOLAR DISORDERS, 5(3), 226–227. -
Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH Life Chart Method
Post, R. M., Denicoff, K. D., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T. M., … Nolen, W. A. (2003). Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH Life Chart Method. JOURNAL OF CLINICAL PSYCHIATRY, 64(6), 680–690. -
Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up
Altshuler, L., Suppes, T., Black, D., Nolen, W. A., Keck, P. E., Frye, M. A., … Post, R. (2003). Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up. AMERICAN JOURNAL OF PSYCHIATRY, 160(7), 1252–1262. -
Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study
Tohen, M., Ketter, T. A., Zarate, C. A., Suppes, T., Frye, M., Altshuler, L., … Baker, R. W. (2003). Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study. AMERICAN JOURNAL OF PSYCHIATRY, 160(7), 1263–71. -
Psychosis in bipolar disorder: Phenomenology and impact on morbidity and course of illness
Keck, P. E., McElroy, S. L., Havens, J. R., Altshuler, L. L., Nolen, W. A., Frye, M. A., … Post, R. M. (2003). Psychosis in bipolar disorder: Phenomenology and impact on morbidity and course of illness. COMPREHENSIVE PSYCHIATRY, 44(4), 263–269. -
CLOZAPINE IN THE TREATMENT OF DYSPHORIC MANIA
Suppes, T., McElroy, S. L., Gilbert, J., Dessain, E. C., & Cole, J. O. (1992). CLOZAPINE IN THE TREATMENT OF DYSPHORIC MANIA. BIOLOGICAL PSYCHIATRY, 32(3), 270–280. -
An overview of recent findings of the Stanley Foundation Bipolar Network (Part I)
Post, R. M., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T. M., Keck, P. E., … Walden, J. (2003). An overview of recent findings of the Stanley Foundation Bipolar Network (Part I). BIPOLAR DISORDERS, 5(5), 310–319. -
A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network
Post, R. M., Leverich, G. S., Nolen, W. A., Kupka, R. W., Altshuler, L. L., Frye, M. A., … Walden, J. (2003). A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network. BIPOLAR DISORDERS, 5(6), 396–406. -
The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: a psychometric evaluation
Trivedi, M. H., Rush, A. J., Ibrahim, H. M., Carmody, T. J., Biggs, M. M., Suppes, T., … Kashner, T. M. (2004). The Inventory of Depressive Symptomatology, Clinician Rating (IDS-C) and Self-Report (IDS-SR), and the Quick Inventory of Depressive Symptomatology, Clinician Rating (QIDS-C) and Self-Report (QIDS-SR) in public sector patients with mood disorders: a psychometric evaluation. PSYCHOLOGICAL MEDICINE, 34(1), 73–82. -
A 52-week, open-label continuation study of lamotrigine in the treatment of bipolar depression
McElroy, S. L., Zarate, C. A., Cookson, J., Suppes, T., Huffman, R. F., Greene, P., & Ascher, J. (2004). A 52-week, open-label continuation study of lamotrigine in the treatment of bipolar depression. JOURNAL OF CLINICAL PSYCHIATRY, 65(2), 204–210. -
Self-reported participation in nonpharmacologic treatments for bipolar disorder
Dennehy, E. B., GONZALEZ, R., & Suppes, T. (2004). Self-reported participation in nonpharmacologic treatments for bipolar disorder. JOURNAL OF CLINICAL PSYCHIATRY, 65(2), 278–278. -
Development of a computerized assessment of clinician adherence to a treatment guideline for patients with bipolar disorder
Dennehy, E. B., Suppes, T., Rush, A. J., Crismon, M. L., Witte, B., & Webster, J. (2004). Development of a computerized assessment of clinician adherence to a treatment guideline for patients with bipolar disorder. JOURNAL OF PSYCHIATRIC RESEARCH, 38(3), 285–294. -
Treatment of rapid-cycling bipolar disorder
Post, R. M., Chang, K. D., Suppes, T., & Ginsberg, D. L. (2004). Treatment of rapid-cycling bipolar disorder. CNS SPECTRUMS, 9(2), 1–10. -
Management of bipolar disorder during pregnancy and the postpartum period
Yonkers, K. A., Wisner, K. L., Stowe, Z., Leibenluft, E., Cohen, L., Miller, L., … Altshuler, L. (2004). Management of bipolar disorder during pregnancy and the postpartum period. AMERICAN JOURNAL OF PSYCHIATRY, 161(4), 608–20. -
Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone
Tohen, M., Chengappa, K. N. R., Suppes, T., Baker, R. W., Zarate, C. A., Bowden, C. L., … Calabrese, J. R. (2004). Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone. BRITISH JOURNAL OF PSYCHIATRY, 184, 337–345. -
Use of quetiapine in bipolar disorder: a case series with prospective evaluation
Suppes, T., McElroy, S. L., Keck, P. E., Altshuler, L., Frye, M. A., Grunze, H., … Post, R. M. (2004). Use of quetiapine in bipolar disorder: a case series with prospective evaluation. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 19(3), 173–174. -
Quetiapine with lithium or divalproex for the treatment of bipolar mania: a randomized, double-blind, placebo-controlled study
Sachs, G., Chengappa, K. N. R., Suppes, T., MULLEN, J. A., Brecher, M., Devine, N. A., & Sweitzer, D. E. (2004). Quetiapine with lithium or divalproex for the treatment of bipolar mania: a randomized, double-blind, placebo-controlled study. BIPOLAR DISORDERS, 6(3), 213–223. -
Response to clozapine of rapid cycling versus non-cycling patients with a history of mania
Suppes, T., Ozcan, M. E., & Carmody, T. (2004). Response to clozapine of rapid cycling versus non-cycling patients with a history of mania. BIPOLAR DISORDERS, 6(4), 329–332. -
Clinical results for patients with major depressive disorder in the Texas medication algorithm project
Trivedi, M. H., Rush, A. J., Crismon, M. L., Kashner, T. M., Toprac, M. G., Carmody, T. J., … Shon, S. P. (2004). Clinical results for patients with major depressive disorder in the Texas medication algorithm project. ARCHIVES OF GENERAL PSYCHIATRY, 61(7), 669–680. -
Development of the Brief Bipolar Disorder Symptom Scale for patients with bipolar disorder
Dennehy, E. B., Suppes, T., Crismon, M. L., Toprac, M., Carmody, T. J., & Rush, A. J. (2004). Development of the Brief Bipolar Disorder Symptom Scale for patients with bipolar disorder. PSYCHIATRY RESEARCH, 127(1-2), 137–145. -
Correlates of 1-year prospective outcome in bipolar disorder: Results from the Stanley foundation bipolar network
Nolen, W. A., Luckenbaugh, D. A., Altshuler, L. L., Suppes, T., McElroy, S. L., Frye, M. A., … Post, R. M. (2004). Correlates of 1-year prospective outcome in bipolar disorder: Results from the Stanley foundation bipolar network. AMERICAN JOURNAL OF PSYCHIATRY, 161(8), 1447–1454. -
Adjunctive stimulant use in patients with bipolar disorder: treatment of residual depression and sedation
Carlson, P. J., Merlock, M. C., & Suppes, T. (2004). Adjunctive stimulant use in patients with bipolar disorder: treatment of residual depression and sedation. BIPOLAR DISORDERS, 6(5), 416–420. -
Low doses of clozapine may stabilize treatment-resistant bipolar patients
Fehr, B. S., Ozcan, M. E., & Suppes, T. (2005). Low doses of clozapine may stabilize treatment-resistant bipolar patients. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 255(1), 10–14. -
Effects of clozapine on sleep in bipolar and schizoaffective disorders
Armitage, R., Cole, D., Suppes, T., & Ozcan, M. E. (2004). Effects of clozapine on sleep in bipolar and schizoaffective disorders. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 28(7), 1065–1070. -
The Texas Medication Algorithm Project: Clinical results for schizophrenia
Miller, A. L., Crismon, M. L., Rush, A. J., Chiles, J., Kashner, T. M., Toprac, M., … Shon, S. (2004). The Texas Medication Algorithm Project: Clinical results for schizophrenia. SCHIZOPHRENIA BULLETIN, 30(3), 627–647. -
A cautionary note when using zonisamide in youths a case report of association with toxic epidermal necrolysis
Majeres, K. D., & Suppes, T. (2004). A cautionary note when using zonisamide in youths a case report of association with toxic epidermal necrolysis. JOURNAL OF CLINICAL PSYCHIATRY, 65(12), 1720–1720. -
Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorder
Post, R. M., Altshuler, L. L., Frye, M. A., Suppes, T., McElroy, S. L., Keck, P. E., … Grunze, H. (2005). Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorder. JOURNAL OF CLINICAL PSYCHIATRY, 66(3), 370–374. -
The efficacy of light therapy in the treatment of mood disorders: A review and meta-analysis of the evidence
Golden, R. N., Gaynes, B. N., Ekstrom, R. D., Hamer, R. M., JACOBSEN, F. M., Suppes, T., … Nemeroff, C. B. (2005). The efficacy of light therapy in the treatment of mood disorders: A review and meta-analysis of the evidence. AMERICAN JOURNAL OF PSYCHIATRY, 162(4), 656–662. -
Open-label adjunctive zonisamide in the treatment of bipolar disorders: A prospective trial
McElroy, S. L., Suppes, T., Keck, P. E., Black, D., Frye, M. A., Altshuler, L. L., … Post, R. M. (2005). Open-label adjunctive zonisamide in the treatment of bipolar disorders: A prospective trial. JOURNAL OF CLINICAL PSYCHIATRY, 66(5), 617–624. -
Reproductive function and risk for PCOS in women treated for bipolar disorder
Rasgon, N. L., Altshuler, L. L., Fairbanks, L., Elman, S., Bitran, J., Labarca, R., … Mintz, J. (2005). Reproductive function and risk for PCOS in women treated for bipolar disorder. BIPOLAR DISORDERS, 7(3), 246–59. -
Brief Psychiatric Rating Scale Expanded Version: How do new items affect factor structure?
Velligan, D., Prihoda, T., Dennehy, E., Biggs, M., Shores-Wilson, K., Crismon, M. L., … Shon, S. (2005). Brief Psychiatric Rating Scale Expanded Version: How do new items affect factor structure? PSYCHIATRY RESEARCH, 135(3), 217–228. -
Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients
Kupka, R. W., Luckenbaugh, D. A., Post, R. M., Suppes, T., Altshuler, L. L., Keck, P. E., … Nolen, W. A. (2005). Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients. AMERICAN JOURNAL OF PSYCHIATRY, 162(7), 1273–1280. -
The Texas Implementation of Medication Algorithms: Update to the algorithms for treatment of bipolar I disorder
Suppes, T., Dennehy, E. B., Hirschfeld, R. M. A., Altshuler, L. L., Bowden, C. L., Calabrese, J. R., … Swann, A. C. (2005). The Texas Implementation of Medication Algorithms: Update to the algorithms for treatment of bipolar I disorder. JOURNAL OF CLINICAL PSYCHIATRY, 66(7), 870–86. -
Challenges in the management of bipolar depression
Suppes, T., Kelly, D. I., & Perla, J. M. (2005). Challenges in the management of bipolar depression. Presented at the Roundtable Meeting on the Burden of Bipolar Illness, NEW YORK,NY: PHYSICIANS POSTGRADUATE PRESS. -
Atypical antipsychotics in bipolar depression: Potential mechanisms of action
Yatham, L. N., Goldstein, J. M., Vieta, E., Bowden, C. L., Grunze, H., Post, R. M., … Calabrese, J. R. (2005). Atypical antipsychotics in bipolar depression: Potential mechanisms of action. Presented at the Roundtable Meeting on the Burden of Bipolar Illness, NEW YORK,NY: PHYSICIANS POSTGRADUATE PRESS. -
Quality of care measures for the treatment of bipolar disorder
Duffy, F. F., Narrow, W., West, J. C., Fochtmann, L. J., Kahn, D. A., Suppes, T., … Regier, D. (2005). Quality of care measures for the treatment of bipolar disorder. PSYCHIATRIC QUARTERLY, 76(3), 213–230. -
Does provider adherence to a treatment guideline change clinical outcomes for patients with bipolar disorder? Results from the Texas Medication Algorithm Project
Dennehy, E. B., Suppes, T., Rush, A. J., Miller, A. L., Trivedi, M. H., Crismon, M. L., … Kashner, T. M. (2005). Does provider adherence to a treatment guideline change clinical outcomes for patients with bipolar disorder? Results from the Texas Medication Algorithm Project. PSYCHOLOGICAL MEDICINE, 35(12), 1695–1706. -
Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network - A sex-specific phenomenon
Suppes, T., Mintz, J., McElroy, S. L., Altshuler, L. L., Kupka, R. W., Frye, M. A., … Post, R. M. (2005). Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network - A sex-specific phenomenon. ARCHIVES OF GENERAL PSYCHIATRY, 62(10), 1089–1096. -
Rapid versus non-rapid cycling as a predictor of response to olanzapine and divalproex sodium for bipolar mania and maintenance of remission: Post hoc analyses of 47-week data
Suppes, T., Brown, E., Schuh, L. M., Baker, R. W., & Tohen, M. (2005). Rapid versus non-rapid cycling as a predictor of response to olanzapine and divalproex sodium for bipolar mania and maintenance of remission: Post hoc analyses of 47-week data. JOURNAL OF AFFECTIVE DISORDERS, 89(1-3), 69–77. -
Treatment of bipolar mania with atypical antipsychotics.
Chengappa, K. N. R., Suppes, T., & Berk, M. (2004). Treatment of bipolar mania with atypical antipsychotics. Expert Review of Neurotherapeutics, 4(6), S17–25. -
Valproate is associated with new-onset oligoamenorrhea with hyperandrogenism in women with bipolar disorder
Joffe, H., Cohen, L. S., Suppes, T., McLaughlin, W. L., Lavori, P., Adams, J. M., … Sachs, G. S. (2006). Valproate is associated with new-onset oligoamenorrhea with hyperandrogenism in women with bipolar disorder. BIOLOGICAL PSYCHIATRY, 59(11), 1078–86. -
Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and Bupropion as adjuncts to mood stabilizers
Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T., McElroy, S. L., Keck, P. E., … Post, R. M. (2006). Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and Bupropion as adjuncts to mood stabilizers. AMERICAN JOURNAL OF PSYCHIATRY, 163(2), 232–239. -
Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressants
Altshuler, L. L., Suppes, T., Black, D. O., Nolen, W. A., Leverich, G., Keck, P. E., … Post, R. (2006). Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressants. AMERICAN JOURNAL OF PSYCHIATRY, 163(2), 313–315. -
An empirical analysis of cost outcomes of the Texas medication algorithm project
Kashner, T. M., Rush, A. J., Crismon, M. L., Toprac, M., Carmody, T. J., Miller, A. L., … Suppes, T. (2006). An empirical analysis of cost outcomes of the Texas medication algorithm project. PSYCHIATRIC SERVICES, 57(5), 648–659. -
Recurrence in bipolar I disorder: A post hoc analysis excluding relapses in two double-blind maintenance studies
Calabrese, J. R., Goldberg, J. F., Ketter, T. A., Suppes, T., Frye, M., White, R., … Thompson, T. R. (2006). Recurrence in bipolar I disorder: A post hoc analysis excluding relapses in two double-blind maintenance studies. BIOLOGICAL PSYCHIATRY, 59(11), 1061–64. -
Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder
Keck, P. E., Mintz, J., McElroy, S. L., Freeman, M. P., Frye, T. S. M. A., Altshuler, L. L., … Post, R. M. (2006). Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder. BIOLOGICAL PSYCHIATRY, 60(9), 1020–1022. -
Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline
Post, R. M., Altshuler, L. L., Leverich, G. S., Frye, M. A., Nolen, W. A., Kupka, R. W., … Mintz, J. (2006). Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline. BRITISH JOURNAL OF PSYCHIATRY, 189, 124–131. -
Omega-3 fatty acids in bipolar disorder: Clinical and research considerations
Marangell, L. B., Suppes, T., Ketter, T. A., Dennehy, E. B., Zboyan, H., Kertz, B., … Sachs, G. (2006). Omega-3 fatty acids in bipolar disorder: Clinical and research considerations. PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 75(4-5), 315–21. -
Longitudinal follow-up of reproductive and metabolic features of valproate-associated polycystic ovarian syndrome features: A preliminary report
Joffe, H., Cohen, L. S., Suppes, T., Hwang, C. H., Molay, F., Adams, J. M., … Hall, J. E. (2006). Longitudinal follow-up of reproductive and metabolic features of valproate-associated polycystic ovarian syndrome features: A preliminary report. BIOLOGICAL PSYCHIATRY, 60(12), 1378–1381. -
Implementation of the texas medication algorithm project patient and family education program
Toprac, M. G., Dennehy, E. B., Carmody, T. J., Crismon, M. L., Miller, A. L., Trivedi, M. H., … Rush, A. J. (2006). Implementation of the texas medication algorithm project patient and family education program. JOURNAL OF CLINICAL PSYCHIATRY, 67(9), 1362–1372. -
Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: Results of a large, multisite study
Altshuler, L. L., Post, R. M., Black, D. O., Keck, P. E., Nolen, W. A., Frye, M. A., … Mintz, J. (2006). Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: Results of a large, multisite study. JOURNAL OF CLINICAL PSYCHIATRY, 67(10), 1551–1560. -
New findings from the Bipolar Collaborative Network: clinical implications for therapeutics.
Post, R. M., Altshuler, L. L., Frye, M. A., Suppes, T., McElroy, S., Keck, P. E., … Grunze, H. (2006). New findings from the Bipolar Collaborative Network: clinical implications for therapeutics. Current Psychiatry Reports, 8(6), 489–497. -
Incidence and time course of subsyndromal symptoms in patients with bipolar I disorder: An evaluation of 2 placebo-controlled maintenance trials
Frye, M. A., Yatham, L. N., Calabrese, J. R., Bowden, C. L., Ketter, T. A., Suppes, T., … Thompson, T. R. (2006). Incidence and time course of subsyndromal symptoms in patients with bipolar I disorder: An evaluation of 2 placebo-controlled maintenance trials. JOURNAL OF CLINICAL PSYCHIATRY, 67(11), 1721–28. -
Open-label aripiprazole in the treatment of acute bipolar depression: A prospective pilot trial
McElroy, S. L., Suppes, T., Frye, M. A., Altshuler, L. L., Stanford, K., Martens, B., … Keck, P. E. (2007). Open-label aripiprazole in the treatment of acute bipolar depression: A prospective pilot trial. JOURNAL OF AFFECTIVE DISORDERS, 101(1-3), 275–281. -
Alcoholism and anxiety in bipolar illness: Differential lifetime anxiety comorbidity in bipolar I women with and without alcoholism
Levander, E., Frye, M. A., McElroy, S., Suppes, T., Grunze, H., Nolen, W. A., … Post, R. M. (2007). Alcoholism and anxiety in bipolar illness: Differential lifetime anxiety comorbidity in bipolar I women with and without alcoholism. JOURNAL OF AFFECTIVE DISORDERS, 101(1-3), 211–217. -
Tranylcypromine vs. lamotrigine in the treatment of refractory bipolar depression: a failed but clinically useful study
Nolen, W. A., Kupka, R. W., Hellemann, G., Frye, M. A., Altshuler, L. L., Leverich, G. S., … Post, R. M. (2007). Tranylcypromine vs. lamotrigine in the treatment of refractory bipolar depression: a failed but clinically useful study. ACTA PSYCHIATRICA SCANDINAVICA, 115(5), 360–365. -
The poor prognosis of childhood-onset bipolar disorder
Leverich, G. S., Post, R. M., Keck, P. E., Altshuler, L. L., Frye, M. A., Kupka, R. W., … Luckenbaugh, D. (2007). The poor prognosis of childhood-onset bipolar disorder. JOURNAL OF PEDIATRICS, 150(5), 485–490. -
Comparison of two anticonvulsants in a randomized, single-blind treatment of hypomanic symptoms in patients with bipolar disorder
Suppes, T., Kelly, D. I., Hlynan, L. S., Snow, D. E., Sureddi, S., Foster, B., & Curley, E. (2007). Comparison of two anticonvulsants in a randomized, single-blind treatment of hypomanic symptoms in patients with bipolar disorder. AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, 41(5), 397–402. -
Awareness of Metabolic Concerns and Perceived Impact of Pharmacotherapy in Patients with Bipolar Disorder: A Survey of 500 US Psychiatrists
Suppes, T., McElroy, S. L., & Hirschfeld, R. (2007). Awareness of Metabolic Concerns and Perceived Impact of Pharmacotherapy in Patients with Bipolar Disorder: A Survey of 500 US Psychiatrists. PSYCHOPHARMACOLOGY BULLETIN, 40(2), 22–37. -
Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder
Goldberg, J. F., Bowden, C. L., Calabrese, J. R., Ketter, T. A., Dann, R. S., Frye, M. A., … Post, R. M. (2008). Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder. BIOLOGICAL PSYCHIATRY, 63(1), 125–30. -
A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders
McElroy, S. L., Frye, M. A., Altshuler, L. L., Suppes, T., Hellemann, G., Black, D., … Keck, P. E. (2007). A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders. BIPOLAR DISORDERS, 9(4), 426–434. -
Dimensions and the psychosis phenotype
Allardyce, J., Suppes, T., & van Os, J. (2007). Dimensions and the psychosis phenotype. Presented at the Conference on Dimensional Approaches to Psychiatric Classification, BETHESDA,MD: JOHN WILEY & SONS LTD. -
A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression
Frye, M. A., Grunze, H., Suppes, T., McElroy, S. L., Keck, P. E., Walden, J., … Post, R. M. (2007). A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression. AMERICAN JOURNAL OF PSYCHIATRY, 164(8), 1242–1249. -
Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder
Kupka, R. W., Altshuler, L. L., Nolen, W. A., Suppes, T., Luckenbaugh, D. A., Leverich, G. S., … Post, R. M. (2007). Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder. BIPOLAR DISORDERS, 9(5), 531–535. -
Quetiapine for the treatment of bipolar II depression: Analysis of data from two randomized, double-blind, placebo-controlled studies
Suppes, T., Hirschfeld, R. M., Vieta, E., Raines, S., & Paulsson, B. (2008). Quetiapine for the treatment of bipolar II depression: Analysis of data from two randomized, double-blind, placebo-controlled studies. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 9(3), 198–211. -
Efficacy and safety of aripiprazole in subpopulations with acute manic or mixed episodes of bipolar I disorder
Suppes, T., Eudicone, J., McQuade, R., Pikalov, A., & Carlson, B. (2008). Efficacy and safety of aripiprazole in subpopulations with acute manic or mixed episodes of bipolar I disorder. JOURNAL OF AFFECTIVE DISORDERS, 107(1-3), 145–154. -
Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network
Suppes, T., Kelly, D. I., Keck, P. E., McElroy, S. L., Altshuler, L. L., Mintz, J., … Grunze, H. (2007). Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 22(6), 376–381. -
Clinical implications of anti psychotic-induced hyperprolactinemia in patients with schizophrenia spectrum or bipolar spectrum disorders - Recent developments and current perspectives
Byerly, M., Suppes, T., Tran, Q.-V., & Baker, R. A. (2007). Clinical implications of anti psychotic-induced hyperprolactinemia in patients with schizophrenia spectrum or bipolar spectrum disorders - Recent developments and current perspectives. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 27(6), 639–661. -
Awareness of metabolic concerns in patients with bipolar disorder: A survey of European psychiatrists
Bauer, M., Lecrubier, Y., & Suppes, T. (2008). Awareness of metabolic concerns in patients with bipolar disorder: A survey of European psychiatrists. EUROPEAN PSYCHIATRY, 23(3), 169–177. -
Bipolar II disorder: arguments for and against a distinct diagnostic entity
Vieta, E., & Suppes, T. (2008). Bipolar II disorder: arguments for and against a distinct diagnostic entity. BIPOLAR DISORDERS, 10(1), 163–178. -
A 1-year pilot study of vagus nerve stimulation in treatment-resistant rapid-cycling bipolar disorder
Marangell, L. B., Suppes, T., Zboyan, H. A., Prashad, S. J., Fischer, G., Snow, D., … Allen, J. C. (2008). A 1-year pilot study of vagus nerve stimulation in treatment-resistant rapid-cycling bipolar disorder. JOURNAL OF CLINICAL PSYCHIATRY, 69(2), 183–189. -
Incidence of childhood-onset bipolar illness in the USA and Europe
Post, R. M., Luckenbaugh, D. A., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T., … Walden, J. (2008). Incidence of childhood-onset bipolar illness in the USA and Europe. BRITISH JOURNAL OF PSYCHIATRY, 192(2), 150–151. -
Are bipolar mood symptoms affected by the phase of the menstrual cycle?
Shivakumar, G., Bernstein, I. H., & Suppes, T. (2008). Are bipolar mood symptoms affected by the phase of the menstrual cycle? JOURNAL OF WOMENS HEALTH, 17(3), 473–478. -
A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression
Suppes, T., Marangell, L. B., Bernstein, I. H., Kelly, D. I., Fischer, E. G., Zboyan, H. A., … Gonzalez, R. (2008). A single blind comparison of lithium and lamotrigine for the treatment of bipolar II depression. JOURNAL OF AFFECTIVE DISORDERS, 111(2-3), 334–343. -
An investigation of water lithium concentrations and rates of violent acts in 11 texas counties: Can an association be easily shown?
Gonzalez, R., Bernstein, I., & Suppes, T. (2008). An investigation of water lithium concentrations and rates of violent acts in 11 texas counties: Can an association be easily shown? JOURNAL OF CLINICAL PSYCHIATRY, 69(2), 325–326. -
RISK OF RECURRENCE FOLLOWING DISCONTINUATION OF LITHIUM TREATMENT IN BIPOLAR DISORDER
Suppes, T., BALDESSARINI, R. J., Faedda, G. L., & Tohen, M. (1991). RISK OF RECURRENCE FOLLOWING DISCONTINUATION OF LITHIUM TREATMENT IN BIPOLAR DISORDER. ARCHIVES OF GENERAL PSYCHIATRY, 48(12), 1082–1088. -
Efficacy of quetiapine monotherapy for the treatment of depressive episodes in bipolar I disorder: A post hoc analysis of combined results from 2 double-blind, randomized, placebo-controlled studies
Weisler, R. H., Calabrese, J. R., Thase, M. E., Arvekvist, R., Stening, G., Paulsson, B., & Suppes, T. (2008). Efficacy of quetiapine monotherapy for the treatment of depressive episodes in bipolar I disorder: A post hoc analysis of combined results from 2 double-blind, randomized, placebo-controlled studies. JOURNAL OF CLINICAL PSYCHIATRY, 69(5), 769–782. -
Efficacy and safety of quetiapine in combination with lithium or divalproex for maintenance of patients with bipolar I disorder (international trial 126)
Vieta, E., Suppes, T., Eggens, I., Persson, I., Paulsson, B., & Brecher, M. (2008). Efficacy and safety of quetiapine in combination with lithium or divalproex for maintenance of patients with bipolar I disorder (international trial 126). JOURNAL OF AFFECTIVE DISORDERS, 109(3), 251–263. -
Correlates of Treatment-Emergent Mania Associated With Antidepressant Treatment in Bipolar Depression
Frye, M. A., Helleman, G., McElroy, S. L., Altshuler, L. L., Black, D. O., Keck, P. E., … Suppes, T. (2009). Correlates of Treatment-Emergent Mania Associated With Antidepressant Treatment in Bipolar Depression. AMERICAN JOURNAL OF PSYCHIATRY, 166(2), 164–172. -
Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety
Sheehan, D. V., McElroy, S. L., Harnett-Sheehan, K., Keck, P. E., Janavs, J., Rogers, J., … Suppes, T. (2009). Randomized, placebo-controlled trial of risperidone for acute treatment of bipolar anxiety. JOURNAL OF AFFECTIVE DISORDERS, 115(3), 376–385. -
Depressive relapse during lithium treatment associated with increased serum thyroid-stimulating hormone: results from two placebo-controlled bipolar I maintenance studies
Frye, M. A., Yatham, L., Ketter, T. A., Goldberg, J., Suppes, T., Calabrese, J. R., … Adams, B. (2009). Depressive relapse during lithium treatment associated with increased serum thyroid-stimulating hormone: results from two placebo-controlled bipolar I maintenance studies. ACTA PSYCHIATRICA SCANDINAVICA, 120(1), 10–13. -
Maintenance Treatment for Patients With Bipolar I Disorder: Results From a North American Study of Quetiapine in Combination With Lithium or Divalproex (Trial 127)
Suppes, T., Vieta, E., Liu, S., Brecher, M., & Paulsson, B. (2009). Maintenance Treatment for Patients With Bipolar I Disorder: Results From a North American Study of Quetiapine in Combination With Lithium or Divalproex (Trial 127). AMERICAN JOURNAL OF PSYCHIATRY, 166(4), 476–88. -
Impact of Antidepressant Continuation After Acute Positive or Partial Treatment Response for Bipolar Depression: A Blinded, Randomized Study
Altshuler, L. L., Post, R. M., Hellemann, G., Leverich, G. S., Nolen, W. A., Frye, M. A., … Suppes, T. (2009). Impact of Antidepressant Continuation After Acute Positive or Partial Treatment Response for Bipolar Depression: A Blinded, Randomized Study. JOURNAL OF CLINICAL PSYCHIATRY, 70(4), 450–457. -
The Safety, Acceptability, and Effectiveness of Acupuncture as an Adjunctive Treatment for Acute Symptoms in Bipolar Disorder
Dennehy, E. B., Schnyer, R., Bernstein, I. H., Gonzalez, R., Shivakumar, G., Kelly, D. I., … Suppes, T. (2009). The Safety, Acceptability, and Effectiveness of Acupuncture as an Adjunctive Treatment for Acute Symptoms in Bipolar Disorder. JOURNAL OF CLINICAL PSYCHIATRY. PITTSBURGH,PA,PA,PA,PA,PA,PA,PA,PA,PA: PHYSICIANS POSTGRADUATE PRESS. -
A psychometric evaluation of the clinician-rated Quick Inventory of Depressive Symptomatology (QIDS-C-16) in patients with bipolar disorder
Bernstein, I. H., Rush, A. J., Suppes, T., Trivedi, M. H., Woo, A., Kyutoku, Y., … Carmody, T. J. (2009). A psychometric evaluation of the clinician-rated Quick Inventory of Depressive Symptomatology (QIDS-C-16) in patients with bipolar disorder. INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, 18(2), 138–146. -
The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders
Tohen, M., Frank, E., Bowden, C. L., Colom, F., Ghaemi, S. N., Yatham, L. N., … Berk, M. (2009). The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders. BIPOLAR DISORDERS, 11(5), 453–73. -
Mood Stabilization and Destabilization During Acute and Continuation Phase Treatment for Bipolar I Disorder With Lamotrigine or Placebo
Goldberg, J. F., Calabrese, J. R., Saville, B. R., Frye, M. A., Ketter, T. A., Suppes, T., … Goodwin, F. K. (2009). Mood Stabilization and Destabilization During Acute and Continuation Phase Treatment for Bipolar I Disorder With Lamotrigine or Placebo. JOURNAL OF CLINICAL PSYCHIATRY, 70(9), 1273–80. -
Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression
Suppes, T., Datto, C., Minkwitz, M., Nordenhem, A., Walker, C., & Darko, D. (2010). Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression. JOURNAL OF AFFECTIVE DISORDERS, 121(1-2), 106–15. -
Genetics and intermediate phenotypes of the schizophrenia bipolar disorder boundary
Ivleva, E. I., Morris, D. W., Moates, A. F., Suppes, T., Thaker, G. K., & Tamminga, C. A. (2010). Genetics and intermediate phenotypes of the schizophrenia bipolar disorder boundary. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 34(6), 897–921. -
Gender and Depressive Symptoms in 711 Patients With Bipolar Disorder Evaluated Prospectively in the Stanley Foundation Bipolar Treatment Outcome Network
Altshuler, L. L., Kupka, R. W., Hellemann, G., Frye, M. A., Sugar, C. A., McElroy, S. L., … Zermeno, M. (2010). Gender and Depressive Symptoms in 711 Patients With Bipolar Disorder Evaluated Prospectively in the Stanley Foundation Bipolar Treatment Outcome Network. AMERICAN JOURNAL OF PSYCHIATRY, 167(6), 708–15. -
Is There a Role for Antidepressants in the Treatment of Bipolar II Depression?
Suppes, T. (2010). Is There a Role for Antidepressants in the Treatment of Bipolar II Depression? AMERICAN JOURNAL OF PSYCHIATRY, 167(7), 738–40. -
The Quick Inventory of Depressive Symptomatology (Clinician and Self-Report Versions) in Patients With Bipolar Disorder
Bernstein, I. H., Rush, A. J., Suppes, T., Kyotoku, Y., & Warden, D. (2010). The Quick Inventory of Depressive Symptomatology (Clinician and Self-Report Versions) in Patients With Bipolar Disorder. CNS SPECTRUMS, 15(6), 367–73. -
Early-Onset Bipolar Disorder and Treatment Delay Are Risk Factors for Poor Outcome in Adulthood
Post, R. M., Leverich, G. S., Kupka, R. W., Keck, P. E., McElroy, S. L., Altshuler, L. L., … Nolen, W. A. (2010). Early-Onset Bipolar Disorder and Treatment Delay Are Risk Factors for Poor Outcome in Adulthood. JOURNAL OF CLINICAL PSYCHIATRY, 71(7), 864–72. -
Prevalence and correlates of eating disorders in 875 patients with bipolar disorder
McElroy, S. L., Frye, M. A., Hellemann, G., Altshuler, L., Leverich, G. S., Suppes, T., … Post, R. M. (2011). Prevalence and correlates of eating disorders in 875 patients with bipolar disorder. JOURNAL OF AFFECTIVE DISORDERS, 128(3), 191–98. -
Complexity of Pharmacologic Treatment Required for Sustained Improvement in Outpatients With Bipolar Disorder
Post, R. M., Altshuler, L. L., Frye, M. A., Suppes, T., Keck, P. E., McElroy, S. L., … Nolen, W. A. (2010). Complexity of Pharmacologic Treatment Required for Sustained Improvement in Outpatients With Bipolar Disorder. JOURNAL OF CLINICAL PSYCHIATRY, 71(9), 1176–86. -
Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany
Post, R. M., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T., Keck, P. E., … Rowe, M. (2011). Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany. INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 26(2), 96–106. -
Characteristics of responders and non-responders to risperidone monotherapy or placebo in co-occurring bipolar disorder and anxiety disorder
Seo, J. S., Jamieson, K., Cosgrove, V., Gwizdowski, I. S., Yang, H., Sheehan, D. V., … Suppes, T. (2013). Characteristics of responders and non-responders to risperidone monotherapy or placebo in co-occurring bipolar disorder and anxiety disorder. EUROPEAN PSYCHIATRY, 28(3), 190–96. -
Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder
Kupfer, D. J., Angst, J., Berk, M., Dickerson, F., Frangou, S., Frank, E., … Zarate, C. A. (2011). Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder. Presented at the 9th International Conference on Bipolar Disorder (ICBD), PITTSBURGH,PA,PA,PA,PA,PA,PA,PA: BLACKWELL SCIENCE PUBL. -
Co-occurrence of Serious or Undiagnosed Medical Conditions With Bipolar Disorder Preventing Clinical Trial Randomization: A Case Series
Feldman, N. S., Gwizdowski, I. S., Fischer, E. G., Yang, H., & Suppes, T. (2012). Co-occurrence of Serious or Undiagnosed Medical Conditions With Bipolar Disorder Preventing Clinical Trial Randomization: A Case Series. JOURNAL OF CLINICAL PSYCHIATRY, 73(6), 874–77. -
Relationship of Prior Antidepressant Exposure to Long-Term Prospective Outcome in Bipolar I Disorder Outpatients
Post, R. M., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T., McElroy, S. L., … Goodwin, F. K. (2012). Relationship of Prior Antidepressant Exposure to Long-Term Prospective Outcome in Bipolar I Disorder Outpatients. JOURNAL OF CLINICAL PSYCHIATRY, 73(7), 924–930. -
Multivariate analysis of bipolar mania: Retrospectively assessed structure of bipolar I manic and mixed episodes in randomized clinical trial participants
Swann, A. C., Suppes, T., Ostacher, M. J., Eudicone, J. M., McQuade, R., Forbes, A., & Carlson, B. X. (2013). Multivariate analysis of bipolar mania: Retrospectively assessed structure of bipolar I manic and mixed episodes in randomized clinical trial participants. JOURNAL OF AFFECTIVE DISORDERS, 144(1-2), 59–64. -
Randomized, placebo-controlled trial of quetiapine XR and divalproex ER monotherapies in the treatment of the anxious bipolar patient
Sheehan, D. V., Harnett-Sheehan, K., Hidalgo, R. B., Janavs, J., McElroy, S. L., Amado, D., & Suppes, T. (2013). Randomized, placebo-controlled trial of quetiapine XR and divalproex ER monotherapies in the treatment of the anxious bipolar patient. JOURNAL OF AFFECTIVE DISORDERS, 145(1), 83–94. -
Long-term efficacy of quetiapine in combination with lithium or divalproex on mixed symptoms in bipolar I disorder
Vieta, E., Suppes, T., Ekholm, B., Udd, M., & Gustafsson, U. (2012). Long-term efficacy of quetiapine in combination with lithium or divalproex on mixed symptoms in bipolar I disorder. JOURNAL OF AFFECTIVE DISORDERS, 142(1-3), 36–44. -
Bipolar Mixed States: An International Society for Bipolar Disorders Task Force Report of Symptom Structure, Course of Illness, and Diagnosis
Swann, A. C., Lafer, B., Perugi, G., Frye, M. A., Bauer, M., Bahk, W.-M., … Suppes, T. (2013). Bipolar Mixed States: An International Society for Bipolar Disorders Task Force Report of Symptom Structure, Course of Illness, and Diagnosis. AMERICAN JOURNAL OF PSYCHIATRY, 170(1), 31–42. -
Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder
Post, R. M., Altshuler, L. L., Leverich, G. S., Frye, M. A., Suppes, T., McElroy, S. L., … Rowe, M. (2013). Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder. JOURNAL OF AFFECTIVE DISORDERS, 147(1-3), 288–94. -
Comparison of objective and subjective assessments of sleep time in subjects with bipolar disorder
Gonzalez, R., Tamminga, C., Tohen, M., & Suppes, T. (2013). Comparison of objective and subjective assessments of sleep time in subjects with bipolar disorder. JOURNAL OF AFFECTIVE DISORDERS, 149(1-3), 363–66. -
First controlled treatment trial of bipolar II hypomania with mixed symptoms: Quetiapine versus placebo.
Suppes, T., Ketter, T. A., Gwizdowski, I. S., Dennehy, E. B., Hill, S. J., Fischer, E. G., … Cosgrove, V. E. (2013). First controlled treatment trial of bipolar II hypomania with mixed symptoms: Quetiapine versus placebo. Journal of Affective Disorders, 150(1), 37–43. -
Informing DSM-5: biological boundaries between bipolar I disorder, schizoaffective disorder, and schizophrenia.
Cosgrove, V. E., & Suppes, T. (2013). Informing DSM-5: biological boundaries between bipolar I disorder, schizoaffective disorder, and schizophrenia. BMC Medicine, 11, 127-? -
Presentation and prevalence of PTSD in a bipolar disorder population: A STEP-BD examination
Hernandez, J. M., Cordova, M. J., Ruzek, J., Reiser, R., Gwizdowski, I. S., Suppes, T., & Ostacher, M. J. (2013). Presentation and prevalence of PTSD in a bipolar disorder population: A STEP-BD examination. JOURNAL OF AFFECTIVE DISORDERS, 150(2), 450–55. -
MAINTENANCE TREATMENT WITH QUETIAPINE WHEN COMBINED WITH EITHER LITHIUM OR DIVALPROEX IN BIPOLAR I DISORDER: ANALYSIS OF TWO LARGE RANDOMIZED, PLACEBO-CONTROLLED TRIALS
Suppes, T., Vieta, E., Gustafsson, U., & Ekholm, B. (2013). MAINTENANCE TREATMENT WITH QUETIAPINE WHEN COMBINED WITH EITHER LITHIUM OR DIVALPROEX IN BIPOLAR I DISORDER: ANALYSIS OF TWO LARGE RANDOMIZED, PLACEBO-CONTROLLED TRIALS. DEPRESSION AND ANXIETY, 30(11), 1089–98. -
THE INFLUENCE OF DOPAMINE ON EPILEPTIFORM BURST ACTIVITY IN HIPPOCAMPAL PYRAMIDAL NEURONS
Suppes, T., Kriegstein, A. R., & Prince, D. A. (1985). THE INFLUENCE OF DOPAMINE ON EPILEPTIFORM BURST ACTIVITY IN HIPPOCAMPAL PYRAMIDAL NEURONS. BRAIN RESEARCH, 326(2), 273–80. -
Cellular and synaptic physiology and epileptogenesis of developing rat neocortical neurons in vitro.
Kriegstein, A. R., Suppes, T., & Prince, D. A. (1987). Cellular and synaptic physiology and epileptogenesis of developing rat neocortical neurons in vitro. Brain Research, 431(2), 161–171. -
SENSITIVITY OF NEURONAL DOPAMINE RESPONSE IN THE SUBSTANTIA-NIGRA AND VENTRAL TEGMENTUM TO CLOZAPINE, METOCLOPRAMIDE AND SCH 23390
Suppes, T., & Pinnock, R. D. (1987). SENSITIVITY OF NEURONAL DOPAMINE RESPONSE IN THE SUBSTANTIA-NIGRA AND VENTRAL TEGMENTUM TO CLOZAPINE, METOCLOPRAMIDE AND SCH 23390. NEUROPHARMACOLOGY, 26(4), 331–337. -
A LATE SLOW DEPOLARIZATION UNMASKED IN THE PRESENCE OF TETRAETHYLAMMONIUM IN NEONATAL RAT SYMPATHETIC NEURONS INVITRO
Suppes, T. (1984). A LATE SLOW DEPOLARIZATION UNMASKED IN THE PRESENCE OF TETRAETHYLAMMONIUM IN NEONATAL RAT SYMPATHETIC NEURONS INVITRO. BRAIN RESEARCH, 293(2), 269–78. -
CHOLINERGIC ENHANCEMENT OF PENICILLIN-INDUCED EPILEPTIFORM DISCHARGES IN PYRAMIDAL NEURONS OF THE GUINEA-PIG HIPPOCAMPUS
Kriegstein, A. R., Suppes, T., & Prince, D. A. (1983). CHOLINERGIC ENHANCEMENT OF PENICILLIN-INDUCED EPILEPTIFORM DISCHARGES IN PYRAMIDAL NEURONS OF THE GUINEA-PIG HIPPOCAMPUS. BRAIN RESEARCH, 266(1), 137–42. -
A CLINICALLY SIGNIFICANT INTERACTION BETWEEN CLOZAPINE AND VALPROATE
COSTELLO, L. E., & Suppes, T. (1995). A CLINICALLY SIGNIFICANT INTERACTION BETWEEN CLOZAPINE AND VALPROATE. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 15(2), 139–141. -
NEUROLOGIC FACTORS PREDICT A FAVORABLE VALPROATE RESPONSE IN BIPOLAR AND SCHIZOAFFECTIVE DISORDERS
Stoll, A. L., Banov, M., KOLBRENER, M., Mayer, P. V., Tohen, M., STRAKOWSKI, S. H., … Cohen, B. M. (1994). NEUROLOGIC FACTORS PREDICT A FAVORABLE VALPROATE RESPONSE IN BIPOLAR AND SCHIZOAFFECTIVE DISORDERS. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 14(5), 311–313. -
STEREOTYPICAL CHANGES IN THE PATTERN AND DURATION OF LONG-TERM POTENTIATION EXPRESSED AT POSTNATAL DAYS 11 AND 15 IN THE RAT HIPPOCAMPUS
Jackson, P. S., Suppes, T., & Harris, K. M. (1993). STEREOTYPICAL CHANGES IN THE PATTERN AND DURATION OF LONG-TERM POTENTIATION EXPRESSED AT POSTNATAL DAYS 11 AND 15 IN THE RAT HIPPOCAMPUS. JOURNAL OF NEUROPHYSIOLOGY, 70(4), 1412–1419. -
CLOZAPINE TREATMENT OF NONPSYCHOTIC RAPID-CYCLING BIPOLAR DISORDER - A REPORT OF 3 CASES
Suppes, T., Phillips, K. A., & JUDD, C. R. (1994). CLOZAPINE TREATMENT OF NONPSYCHOTIC RAPID-CYCLING BIPOLAR DISORDER - A REPORT OF 3 CASES. BIOLOGICAL PSYCHIATRY, 36(5), 338–340. -
OUTCOME AFTER RAPID VS GRADUAL DISCONTINUATION OF LITHIUM TREATMENT IN BIPOLAR DISORDERS
Faedda, G. L., Tondo, L., BALDESSARINI, R. J., Suppes, T., & Tohen, M. (1993). OUTCOME AFTER RAPID VS GRADUAL DISCONTINUATION OF LITHIUM TREATMENT IN BIPOLAR DISORDERS. ARCHIVES OF GENERAL PSYCHIATRY, 50(6), 448–455. -
Capgras' and Fregoli's syndromes in one family
Brown, E. S., Thompson, R., & Suppes, T. (1996). Capgras' and Fregoli's syndromes in one family. JOURNAL OF CLINICAL PSYCHIATRY, 57(3), 137–138. -
Medication optimization during clozapine treatment
Suppes, T., & Rush, A. J. (1996). Medication optimization during clozapine treatment. JOURNAL OF CLINICAL PSYCHIATRY, 57(7), 307–308. -
International psychopharmacology algorithm project report .B. Algorithms for the treatment of bipolar, manic-depressive illness
Suppes, T., Calabrese, J. R., Mitchell, P. B., Pazzaglia, P. J., Potter, W. Z., & Zarin, D. A. (1995). International psychopharmacology algorithm project report .B. Algorithms for the treatment of bipolar, manic-depressive illness. PSYCHOPHARMACOLOGY BULLETIN, 31(3), 469–474. -
Effects of the rate of discontinuing lithium maintenance treatment in bipolar disorders
BALDESSARINI, R. J., Tondo, L., Faedda, G. L., Suppes, T. R., Floris, G., & Rudas, N. (1996). Effects of the rate of discontinuing lithium maintenance treatment in bipolar disorders. JOURNAL OF CLINICAL PSYCHIATRY, 57(10), 441–448. -
Is postictal electrical silence a predictor of response to electroconvulsive therapy?
Suppes, T., Webb, A., Carmody, T., Gordon, E., GUTIERREZESTEINOU, R., Hudson, J. I., & Pope, H. G. (1996). Is postictal electrical silence a predictor of response to electroconvulsive therapy? JOURNAL OF AFFECTIVE DISORDERS, 41(1), 55–58. -
Special treatment issues: Maintaining and discontinuing psychotropic medications
Suppes, T., BALDESSARINI, R. J., Motohashi, N., Tondo, L., & Viguera, A. C. (1997). Special treatment issues: Maintaining and discontinuing psychotropic medications. MOOD DISORDERS, 25, 235–254. -
The atypical antipsychotic sertindole: A case series
Lee, A. M., Knoll, J. L., & Suppes, T. (1997). The atypical antipsychotic sertindole: A case series. JOURNAL OF CLINICAL PSYCHIATRY, 58(9), 410–416. -
DISCONTINUATION OF MAINTENANCE TREATMENT IN BIPOLAR DISORDER - RISKS AND IMPLICATIONS
Suppes, T., BALDESSARINI, R. J., Faedda, G. L., Tondo, L., & Tohen, M. (1993). DISCONTINUATION OF MAINTENANCE TREATMENT IN BIPOLAR DISORDER - RISKS AND IMPLICATIONS. HARVARD REVIEW OF PSYCHIATRY, 1(3), 131–144. -
PEDIATRIC-ONSET BIPOLAR DISORDER - A NEGLECTED CLINICAL AND PUBLIC-HEALTH PROBLEM
Faedda, G. L., BALDESSARINI, R. J., Suppes, T., Tondo, L., Becker, I., & Lipschitz, D. S. (1995). PEDIATRIC-ONSET BIPOLAR DISORDER - A NEGLECTED CLINICAL AND PUBLIC-HEALTH PROBLEM. HARVARD REVIEW OF PSYCHIATRY, 3(4), 171–195. -
Mood symptoms during corticosteroid therapy: A review
Brown, E. S., & Suppes, T. (1998). Mood symptoms during corticosteroid therapy: A review. HARVARD REVIEW OF PSYCHIATRY, 5(5), 239–246. -
Treatment algorithm use to optimize management of symptomatic patients with a history of mania
Suppes, T., Rush, A. J., Kraemer, H. C., & Webb, A. (1998). Treatment algorithm use to optimize management of symptomatic patients with a history of mania. JOURNAL OF CLINICAL PSYCHIATRY. SAN JUAN,PR,PR,PR,PR,PR,PR,PR: PHYSICIANS POSTGRADUATE PRESS. -
What are the new treatments for bipolar disorder?
Rush, A. J., & Suppes, T. (1998). What are the new treatments for bipolar disorder? The Harvard Mental Health Letter / from Harvard Medical School, 14(11), 8-? -
Olanzapine in treatment-resistant bipolar disorder
McElroy, S. L., Frye, M., Denicoff, K., Altshuler, L., Nolen, W., Kupka, R., … Post, R. M. (1998). Olanzapine in treatment-resistant bipolar disorder. JOURNAL OF AFFECTIVE DISORDERS, 49(2), 119–122. -
Clinical experience using gabapentin adjunctively in patients with a history of mania or hypomania
Knoll, J., Stegman, K., & Suppes, T. (1998). Clinical experience using gabapentin adjunctively in patients with a history of mania or hypomania. JOURNAL OF AFFECTIVE DISORDERS, 49(3), 229–233. -
Gastrointestinal side-effects after switch to generic valproic acid
Brown, E. S., Shellhorn, E., & Suppes, T. (1998). Gastrointestinal side-effects after switch to generic valproic acid. PHARMACOPSYCHIATRY, 31(3), 114–114. -
A new algorithm for treating schizophrenia
Pearsall, R., Glick, I. D., Pickard, D., Suppes, T., Tauscher, J., & Jobson, K. O. (1998). A new algorithm for treating schizophrenia. PSYCHOPHARMACOLOGY BULLETIN, 34(3), 349–53. -
Clinical predictors of response vs. non-response to risperidone: CGI-21 scores after 1 week of treatment in a bipolar disorder population with co-occurring panic disorder or generalized anxiety disorder
Raudabaugh, B. J., Hernandez, J. M., Seo, J. S., Jamison, K., Cosgrove, V., Gwizdowski, I. S., … Suppes, T. (2012). Clinical predictors of response vs. non-response to risperidone: CGI-21 scores after 1 week of treatment in a bipolar disorder population with co-occurring panic disorder or generalized anxiety disorder. Presented at the 5th Biennial Conference of the International-Society-for-Bipolar-Disorders, ISTANBUL,TURKEY,TURKEY,TURKEY,TURKEY,TURKEY,TURKEY,TURKEY,TURKEY,TURKEY: WILEY-BLACKWELL. -
A randomized, double-blind, placebo-controlled study of ziprasidone in bipolar disorder with co-occurring lifetime panic or generalized anxiety disorder
Suppes, T., McElroy, S., Cosgrove, V., Gwizdowski, I., & Feldman, N. (2013). A randomized, double-blind, placebo-controlled study of ziprasidone in bipolar disorder with co-occurring lifetime panic or generalized anxiety disorder. Presented at the 10th International Conference on Bipolar Disorder of the International-Society-for-Bipolar-Disorders, MIAMI BEACH,FL,FL,FL,FL,FL,FL: WILEY-BLACKWELL. -
An online intervention for bipolar disorder Moodswings 2.0: www.moodswings.net.au
Cosgrove, V., Fischer, E., Lauder, S., Gwizdowski, I., Feldman, N., Berk, M., … Suppes, T. (2013). An online intervention for bipolar disorder Moodswings 2.0: www.moodswings.net.au. Presented at the 10th International Conference on Bipolar Disorder of the International-Society-for-Bipolar-Disorders, MIAMI BEACH,FL,FL,FL,FL,FL,FL: WILEY-BLACKWELL. -
Acute and continuation pharmacological treatment of children and adolescents with bipolar disorders; a summary of two previous studies
Kowatch, R. A., Carmody, T. J., Suppes, T., Hume, J. H., Kromelis, M., Emslie, G. J., & Weinberg, W. A. (2000). Acute and continuation pharmacological treatment of children and adolescents with bipolar disorders; a summary of two previous studies. ACTA NEUROPSYCHIATRICA, 12(3), 145–149. -
Presentations of depression in bipolar illness
Post, R. A., Denicoff, K. D., Leverich, G. S., Altshuler, L. L., Frye, M. A., Suppes, T. M., … Walden, J. (2002). Presentations of depression in bipolar illness. CLINICAL NEUROSCIENCE RESEARCH, 2(3-4), 142–157. -
Awareness of the metabolic syndrome in patients with bipolar disorder: A comparison of US and European psychiatrists
Lecrubier, Y., Bauer, M., Hirschfeld, R., McElroy, S., & Suppes, T. (2008). Awareness of the metabolic syndrome in patients with bipolar disorder: A comparison of US and European psychiatrists. INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE, 12(3), 187–195. -
Measuring use of outpatient care among mentally ill individuals: a comparison of self reports and provider records
Kashner, T. M., Suppes, T., Rush, A. J., & Altshuler, K. Z. (1999). Measuring use of outpatient care among mentally ill individuals: a comparison of self reports and provider records. EVALUATION AND PROGRAM PLANNING, 22(1), 31–39. -
CELLULAR AND SYNAPTIC PHYSIOLOGY AND EPILEPTOGENESIS OF DEVELOPING RAT NEOCORTICAL NEURONS INVITRO
Kriegstein, A. R., Suppes, T., & Prince, D. A. (1987). CELLULAR AND SYNAPTIC PHYSIOLOGY AND EPILEPTOGENESIS OF DEVELOPING RAT NEOCORTICAL NEURONS INVITRO. DEVELOPMENTAL BRAIN RESEARCH, 34(2), 161–71. -
More stressors prior to and during the course of bipolar illness in patients from the United States compared with the Netherlands and Germany.
Post, R. M., Altshuler, L., Leverich, G., Nolen, W., Kupka, R., Grunze, H., … Rowe, M. (2013). More stressors prior to and during the course of bipolar illness in patients from the United States compared with the Netherlands and Germany. Psychiatry Research, 210(3), 880–86. -
A randomized, double-blind, placebo-controlled study of ziprasidone monotherapy in bipolar disorder with co-occurring lifetime panic or generalized anxiety disorder.
Suppes, T., McElroy, S. L., Sheehan, D. V., Hidalgo, R. B., Cosgrove, V. E., Gwizdowski, I. S., & Feldman, N. S. (2014). A randomized, double-blind, placebo-controlled study of ziprasidone monotherapy in bipolar disorder with co-occurring lifetime panic or generalized anxiety disorder. Journal of Clinical Psychiatry, 75(1), 77–84. -
More medical comorbidities in patients with bipolar disorder from the United States than from the Netherlands and Germany.
Post, R. M., Altshuler, L. L., Leverich, G. S., Frye, M. A., Suppes, T., McElroy, S. L., … Rowe, M. (2014). More medical comorbidities in patients with bipolar disorder from the United States than from the Netherlands and Germany. Journal of Nervous and Mental Disease, 202(4), 265–270. -
More pernicious course of bipolar disorder in the United States than in many European countries: Implications for policy and treatment.
Post, R. M., Altshuler, L., Kupka, R., McElroy, S., Frye, M. A., Rowe, M., … Nolen, W. A. (2014). More pernicious course of bipolar disorder in the United States than in many European countries: Implications for policy and treatment. Journal of Affective Disorders, 160, 27–33. -
Increased parental history of bipolar disorder in the United States: association with early age of onset.
Post, R. M., Leverich, G. S., Kupka, R., Keck, P., McElroy, S., Altshuler, L., … Nolen, W. A. (2014). Increased parental history of bipolar disorder in the United States: association with early age of onset. Acta Psychiatrica Scandinavica, 129(5), 375–82. -
The relationship between affective state and the rhythmicity of activity in bipolar disorder.
Gonzalez, R., Tamminga, C. A., Tohen, M., & Suppes, T. (2014). The relationship between affective state and the rhythmicity of activity in bipolar disorder. Journal of Clinical Psychiatry, 75(4), e317–22. -
Clozapine treatment of children and adolescents with bipolar disorder and schizophrenia: A clinical case series
Kowatch, R. A., Suppes, T., Gilfillan, S. K., Fuentes, R. M., Grannemann, B. D., & Emslie, G. J. (1995). Clozapine treatment of children and adolescents with bipolar disorder and schizophrenia: A clinical case series. JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, 5(4), 241–253. -
Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression.
Suppes, T., Datto, C., Minkwitz, M., Nordenhem, A., Walker, C., & Darko, D. (2014). Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression. Journal of Affective Disorders, 168, 485–93. -
Quetiapine monotherapy in bipolar II depression: combined data from four large, randomized studies.
Young, A. H., Calabrese, J. R., Gustafsson, U., Berk, M., McElroy, S. L., Thase, M. E., … Earley, W. (2013). Quetiapine monotherapy in bipolar II depression: combined data from four large, randomized studies. International Journal of Bipolar Disorders, 1, 10-? -
Methyltestosterone Add-On in Bipolar Depression: A Case Report
Ozcan, M. E., & Suppes, T. (2009). Methyltestosterone Add-On in Bipolar Depression: A Case Report. KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, 19, S166–S167. -
The Stanley Foundation Bipolar Network I. Rationale and methods
Post, R. M., Nolen, W. A., Kupka, R. W., Denicoff, K. D., Leverich, G. S., Keck, P. E., … Walden, J. (2001). The Stanley Foundation Bipolar Network I. Rationale and methods. Presented at the 1st European Stanley-Foundation Symposium on Bipolar Disorder, LONDON,ENGLAND: ROYAL COLLEGE OF PSYCHIATRISTS. -
The Stanley Foundation Bipolar Network 2. Preliminary summary of demographics, course of illness and response to novel treatments
Kupka, R. W., Nolen, W. A., Altshuler, L. L., Denicoff, K. D., Frye, M. A., Leverich, G. S., … Post, R. M. (2001). The Stanley Foundation Bipolar Network 2. Preliminary summary of demographics, course of illness and response to novel treatments. Presented at the 1st European Stanley-Foundation Symposium on Bipolar Disorder, LONDON,ENGLAND: ROYAL COLLEGE OF PSYCHIATRISTS. -
Relationship of clinical course of illness variables to medical comorbidities in 900 adult outpatients with bipolar disorder.
Post, R. M., Altshuler, L., Leverich, G. S., Frye, M. A., Suppes, T., McElroy, S. L., … Rowe, M. (2015). Relationship of clinical course of illness variables to medical comorbidities in 900 adult outpatients with bipolar disorder. Comprehensive Psychiatry, 56, 21–28. -
Illness progression as a function of independent and accumulating poor prognosis factors in outpatients with bipolar disorder in the United States.
Post, R. M., Altshuler, L. L., Leverich, G. S., Nolen, W. A., Kupka, R., Grunze, H., … Rowe, M. (2014). Illness progression as a function of independent and accumulating poor prognosis factors in outpatients with bipolar disorder in the United States. The Primary Care Companion for CNS Disorders, 16(6). -
Patterns of response to aripiprazole, lithium, haloperidol, and placebo across factor scores of mania.
Ostacher, M. J., Suppes, T., Swann, A. C., Eudicone, J. M., Landsberg, W., Baker, R. A., & Carlson, B. X. (2015). Patterns of response to aripiprazole, lithium, haloperidol, and placebo across factor scores of mania. International Journal of Bipolar Disorders, 3, 11-? -
Verbal abuse, like physical and sexual abuse, in childhood is associated with an earlier onset and more difficult course of bipolar disorder
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2015). Verbal abuse, like physical and sexual abuse, in childhood is associated with an earlier onset and more difficult course of bipolar disorder. BIPOLAR DISORDERS, 17(3), 323–30. -
Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany
Post, R. M., Leverich, G. S., Kupka, R., Keck, P. E., McElroy, S. L., Altshuler, L. L., … Nolen, W. A. (2015). Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany. PSYCHIATRIC GENETICS, 25(5), 194–200. -
Letter to the editor in response to 2012 article by Frances and Jones.
Suppes, T., Frank, E., DePaulo, J. R., Davis, L., Zarate, C. A., Angst, J., & Fawcett, J. (2014). Letter to the editor in response to 2012 article by Frances and Jones. Bipolar Disorders, 16(2), 214–15. -
Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany.
Post, R. M., Leverich, G. S., Kupka, R., Keck, P. E., McElroy, S. L., Altshuler, L. L., … Nolen, W. A. (2015). Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany. Psychiatric Genetics, 25(5), 194–200. -
Toward a Valid Animal Model of Bipolar Disorder: How the Research Domain Criteria Help Bridge the Clinical-Basic Science Divide.
Cosgrove, V. E., Kelsoe, J. R., & Suppes, T. (2016). Toward a Valid Animal Model of Bipolar Disorder: How the Research Domain Criteria Help Bridge the Clinical-Basic Science Divide. Biological Psychiatry, 79(1), 62–70. -
Evaluating discussion board engagement in the MoodSwings online self-help program for bipolar disorder: protocol for an observational prospective cohort study.
Gliddon, E., Lauder, S., Berk, L., Cosgrove, V., Grimm, D., Dodd, S., … Berk, M. (2015). Evaluating discussion board engagement in the MoodSwings online self-help program for bipolar disorder: protocol for an observational prospective cohort study. BMC Psychiatry, 15, 243-? -
More illness in offspring of bipolar patients from the US compared to Europe
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2016). More illness in offspring of bipolar patients from the US compared to Europe. JOURNAL OF AFFECTIVE DISORDERS, 191, 180–86. -
Evaluating discussion board engagement in the MoodSwings online self-help program for bipolar disorder: protocol for an observational prospective cohort study
Gliddon, E., Lauder, S., Berk, L., Cosgrove, V., Grimm, D., Dodd, S., … Berk, M. (2015). Evaluating discussion board engagement in the MoodSwings online self-help program for bipolar disorder: protocol for an observational prospective cohort study. BMC PSYCHIATRY, 15. -
Developing a clinical translational neuroscience taxonomy for anxiety and mood disorder: protocol for the baseline-follow up Research domain criteria Anxiety and Depression ("RAD") project
Williams, L. M., Goldstein-Piekarski, A. N., Chowdhry, N., Grisanzio, K. A., Haug, N. A., Samara, Z., … Yesavage, J. (2016). Developing a clinical translational neuroscience taxonomy for anxiety and mood disorder: protocol for the baseline-follow up Research domain criteria Anxiety and Depression ("RAD") project. BMC PSYCHIATRY, 16. -
Developing a clinical translational neuroscience taxonomy for anxiety and mood disorder: protocol for the baseline-follow up Research domain criteria Anxiety and Depression ("RAD") project.
Williams, L. M., Goldstein-Piekarski, A. N., Chowdhry, N., Grisanzio, K. A., Haug, N. A., Samara, Z., … Yesavage, J. (2016). Developing a clinical translational neuroscience taxonomy for anxiety and mood disorder: protocol for the baseline-follow up Research domain criteria Anxiety and Depression ("RAD") project. BMC Psychiatry, 16(1), 68-? -
The Prevalence and Diagnostic Validity of Short-Duration Hypomanic Episodes and Major Depressive Episodes.
Miller, S., Dennehy, E. B., & Suppes, T. (2016). The Prevalence and Diagnostic Validity of Short-Duration Hypomanic Episodes and Major Depressive Episodes. Current Psychiatry Reports, 18(3), 27-? -
Florida Best Practice Psychotherapeutic Medication Guidelines for Adults With Bipolar Disorder: A Novel, Practical, Patient-Centered Guide for Clinicians.
Ostacher, M. J., Tandon, R., & Suppes, T. (2016). Florida Best Practice Psychotherapeutic Medication Guidelines for Adults With Bipolar Disorder: A Novel, Practical, Patient-Centered Guide for Clinicians. Journal of Clinical Psychiatry, 77(7), 920–26. -
Human amygdala engagement moderated by early life stress exposure is a biobehavioral target for predicting recovery on antidepressants
Goldstein-Piekarski, A. N., Korgaonkar, M. S., Green, E., Suppes, T., Schatzberg, A. F., Hastie, T., … Williams, L. M. (2016). Human amygdala engagement moderated by early life stress exposure is a biobehavioral target for predicting recovery on antidepressants. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(42), 11955–60. -
Obesity and obstetric complications are associated with rapid-cycling in Italian patients with bipolar disorder.
Buoli, M., Dell'Osso, B., Caldiroli, A., Carnevali, G. S., Serati, M., Suppes, T., … Altamura, A. C. (2016). Obesity and obstetric complications are associated with rapid-cycling in Italian patients with bipolar disorder. Journal of Affective Disorders, 208, 278–83. -
Increased Suicidal Ideation in Patients with Co-Occurring Bipolar Disorder and Post-Traumatic Stress Disorder.
Carter, J. M., Arentsen, T. J., Cordova, M. J., Ruzek, J., Reiser, R., Suppes, T., & Ostacher, M. J. (2016). Increased Suicidal Ideation in Patients with Co-Occurring Bipolar Disorder and Post-Traumatic Stress Disorder. Archives of Suicide Research , 1–12. -
Obesity and obstetric complications are associated with rapid-cycling in Italian patients with bipolar disorder
Buoli, M., Dell'Osso, B., Caldiroli, A., Carnevali, G. S., Serati, M., Suppes, T., … Altamura, A. C. (2017). Obesity and obstetric complications are associated with rapid-cycling in Italian patients with bipolar disorder. JOURNAL OF AFFECTIVE DISORDERS, 208, 278–83. -
Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network
Miller, S., Suppes, T., Mintz, J., Hellemann, G., Frye, M. A., McElroy, S. L., … Post, R. M. (2016). Mixed Depression in Bipolar Disorder: Prevalence Rate and Clinical Correlates During Naturalistic Follow-Up in the Stanley Bipolar Network. AMERICAN JOURNAL OF PSYCHIATRY, 173(10), 1015–23. -
Progressing MoodSwings. The upgrade and evaluation of MoodSwings 2.0: An online intervention for bipolar disorder.
Lauder, S., Cosgrove, V. E., Gliddon, E., Grimm, D., Dodd, S., Berk, L., … Berk, M. (2017). Progressing MoodSwings. The upgrade and evaluation of MoodSwings 2.0: An online intervention for bipolar disorder. Contemporary Clinical Trials. -
Benefits and harms of low and high second-generation antipsychotics doses for bipolar depression: A meta-analysis
Bartoli, F., Dell'Osso, B., Crocamo, C., Fiorillo, A., Ketter, T. A., Suppes, T., … Carra, G. (2017). Benefits and harms of low and high second-generation antipsychotics doses for bipolar depression: A meta-analysis. JOURNAL OF PSYCHIATRIC RESEARCH, 88, 38–46. -
Online ethics: where will the interface of mental health and the internet lead us?
Cosgrove, V., Gliddon, E., Berk, L., Grimm, D., Lauder, S., Dodd, S., … Suppes, T. (2017). Online ethics: where will the interface of mental health and the internet lead us? International Journal of Bipolar Disorders, 5(1), 26-? -
Guidelines for the recognition and management of mixed depression
Stahl, S. M., Morrissette, D. A., Faedda, G., Fava, M., Goldberg, J. F., Keck, P. E., … McIntyre, R. S. (2017). Guidelines for the recognition and management of mixed depression. CNS SPECTRUMS, 22(2), 203–19. -
Mixed features in major depressive disorder: diagnoses and treatments
Suppes, T., & Ostacher, M. (2017). Mixed features in major depressive disorder: diagnoses and treatments. CNS SPECTRUMS, 22(2), 155–60. -
The ENGAGE study: Integrating neuroimaging, virtual reality and smartphone sensing to understand self-regulation for managing depression and obesity in a precision medicine model.
Williams, L. M., Pines, A., Goldstein-Piekarski, A. N., Rosas, L. G., Kullar, M., Sacchet, M. D., … Ma, J. (2018). The ENGAGE study: Integrating neuroimaging, virtual reality and smartphone sensing to understand self-regulation for managing depression and obesity in a precision medicine model. Behaviour Research and Therapy, 101, 58–70. -
MECHANISTIC SELF-REGULATION TARGETS IN INTEGRATED BEHAVIOR THERAPY FOR OBESE AND DEPRESSED ADULTS: RAINBOW-ENGAGE STUDY
Ma, J., Rosas, L. G., Snowden, M., Wandell, B., Bailenson, J., Greenleaf, W., … Williams, L. (2017). MECHANISTIC SELF-REGULATION TARGETS IN INTEGRATED BEHAVIOR THERAPY FOR OBESE AND DEPRESSED ADULTS: RAINBOW-ENGAGE STUDY. ANNALS OF BEHAVIORAL MEDICINE. SPRINGER. -
UNDERSTANDING TREATMENT RESPONSE TO INTEGRATED BEHAVIOR THERAPY FOR COMORBID OBESITY AND DEPRESSION IN PRIMARY CARE
Ma, J., Lv, N., Rosas, L., Xiao, L., Lavori, P., Venditti, E., … Williams, L. (2018). UNDERSTANDING TREATMENT RESPONSE TO INTEGRATED BEHAVIOR THERAPY FOR COMORBID OBESITY AND DEPRESSION IN PRIMARY CARE. ANNALS OF BEHAVIORAL MEDICINE, 52, S129. -
The association between mood state and chronobiological characteristics in bipolar I disorder: a naturalistic, variable cluster analysis-based study
Gonzalez, R., Suppes, T., Zeitzer, J., McClung, C., Tamminga, C., Tohen, M., … Alvarado, A. (2018). The association between mood state and chronobiological characteristics in bipolar I disorder: a naturalistic, variable cluster analysis-based study. INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS, 6, 5. -
A randomized controlled trial of moodswings 2.0: An internet-based self-management program for bipolar disorder
Gliddon, E., Cosgrove, V., Berk, L., Lauder, S., Mohebbi, M., Grimm, D., … Berk, M. (2018). A randomized controlled trial of moodswings 2.0: An internet-based self-management program for bipolar disorder. BIPOLAR DISORDERS, 20, 60. -
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder
Yatham, L. N., Kennedy, S. H., Parikh, S. V., Schaffer, A., Bond, D. J., Frey, B. N., … Berk, M. (2018). Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. BIPOLAR DISORDERS, 20(2), 97–170. -
Efficacy and tolerability of divalproex sodium plus adjunctive quetiapine, lithium, or placebo for hypomanic or manic episodes in outpatients with bipolar I disorder
Fischer, E. G., Cosgrove, V., Suppes, T., Lange, N. K., Gwizdowski, I., Doan, G., & Ostacher, M. (2018). Efficacy and tolerability of divalproex sodium plus adjunctive quetiapine, lithium, or placebo for hypomanic or manic episodes in outpatients with bipolar I disorder. BIPOLAR DISORDERS, 20, 116. -
Anxiety, irritability, and agitation as indicators of bipolar mania with depressive symptoms: a post hoc analysis of two clinical trials
Suppes, T., Eberhard, J., Lemming, O., Young, A. H., & McIntyre, R. S. (2017). Anxiety, irritability, and agitation as indicators of bipolar mania with depressive symptoms: a post hoc analysis of two clinical trials. INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS, 5, 36. -
Bipolar disorders
Vieta, E., Berk, M., Schulze, T. G., Carvalho, A. F., Suppes, T., Calabrese, J. R., … Grande, I. (2018). Bipolar disorders. NATURE REVIEWS DISEASE PRIMERS, 4, 18008. -
User engagement within the moodswings 2.0 online self-guided intervention for bipolar disorder
Cosgrove, V., Gliddon, E., Berk, L., Lauder, S., Grimm, D., Dodd, S., … Berk, M. (2018). User engagement within the moodswings 2.0 online self-guided intervention for bipolar disorder. BIPOLAR DISORDERS, 20, 30. -
Bipolar patients in the us are quadrupally vulnerable and sensitized to a poor outcome: A national public health emergency should be declared
Post, R., Frye, M., Kupka, R., Nolen, W., Altshuler, L., McElroy, S., … Row, M. (2018). Bipolar patients in the us are quadrupally vulnerable and sensitized to a poor outcome: A national public health emergency should be declared. BIPOLAR DISORDERS, 20, 87. -
Depression With Mixed Features in Major Depressive Disorder: A New Diagnosis or There All Along?
Ostacher, M. J., & Suppes, T. (2018). Depression With Mixed Features in Major Depressive Disorder: A New Diagnosis or There All Along? The Journal of Clinical Psychiatry, (2). -
Prevalence of axis II comorbidities in bipolar disorder: relationship to mood state
Post, R. M., Leverich, G. S., McElroy, S., Kupka, R., Suppes, T., Altshuler, L., … Hellemann, G. (2018). Prevalence of axis II comorbidities in bipolar disorder: relationship to mood state. BIPOLAR DISORDERS, 20(4), 303–12. -
Axis II Personality Disorders Are Linked to an Adverse Course of Bipolar Disorder
Post, R. M., McElroy, S., Kupka, R., Suppes, T., Hellemann, G., Nolen, W., … Rowe, M. (2018). Axis II Personality Disorders Are Linked to an Adverse Course of Bipolar Disorder. JOURNAL OF NERVOUS AND MENTAL DISEASE, 206(6), 469–72. -
Monitoring for antidepressant-associated adverse events in the treatment of patients with major depressive disorder: An international consensus statement
Dodd, S., Mitchell, P. B., Bauer, M., Yatham, L., Young, A. H., Kennedy, S. H., … Berk, M. (2018). Monitoring for antidepressant-associated adverse events in the treatment of patients with major depressive disorder: An international consensus statement. WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY, 19(5), 330–48. -
Early Intervention in Bipolar Disorder
Vieta, E., Salagre, E., Grande, I., Carvalho, A. F., Fernandes, B. S., Berk, M., … Suppes, T. (2018). Early Intervention in Bipolar Disorder. AMERICAN JOURNAL OF PSYCHIATRY, 175(5), 411–26. -
Resting-State Functional Connectivity Dysfunction of the Ventral Striatum in Anhedonia as a Transdiagnostic Process
Samara, Z., Goldstein-Piekarski, A., Suppes, T., Yesavage, J., & Williams, L. (2017). Resting-State Functional Connectivity Dysfunction of the Ventral Striatum in Anhedonia as a Transdiagnostic Process. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
Post hoc analyses of asenapine treatment in pediatric patients with bipolar I disorder: efficacy related to mixed or manic episode, stage of illness, and body weight
Findling, R. L., Earley, W., Suppes, T., Patel, M., Wu, X., Chang, C.-T., & McIntyre, R. S. (2018). Post hoc analyses of asenapine treatment in pediatric patients with bipolar I disorder: efficacy related to mixed or manic episode, stage of illness, and body weight. NEUROPSYCHIATRIC DISEASE AND TREATMENT, 14, 1941–52. -
Multigenerational transmission of liability to psychiatric illness in offspring of parents with bipolar disorder
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2018). Multigenerational transmission of liability to psychiatric illness in offspring of parents with bipolar disorder. BIPOLAR DISORDERS, 20(5), 432–40. -
Major depressive disorder with subthreshold hypomania (mixed features): Clinical characteristics of patients entered in a multiregional, placebo-controlled study
Targum, S. D., Suppes, T., Pendergrass, J. C., Lee, S., Silva, R., Cucchiaro, J., & Loebel, A. (2016). Major depressive disorder with subthreshold hypomania (mixed features): Clinical characteristics of patients entered in a multiregional, placebo-controlled study. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 68, 9–14. -
Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition.
Hidalgo-Mazzei, D., Berk, M., Cipriani, A., Cleare, A. J., Florio, A. D., Dietch, D., … Stokes, P. R. (2018). Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition. The British Journal of Psychiatry : the Journal of Mental Science, 1–9. -
A randomized controlled trial of MoodSwings 2.0: An internet-based self-management program for bipolar disorder
Gliddon, E., Cosgrove, V., Berk, L., Lauder, S., Mohebbi, M., Grimm, D., … Berk, M. (2019). A randomized controlled trial of MoodSwings 2.0: An internet-based self-management program for bipolar disorder. BIPOLAR DISORDERS, 21(1), 28–39. -
REPRODUCTIVE HEALTH AND BIPOLAR DISORDER
Ketter, T. A., Suppes, T., Morrell, M. J., Rasgon, N., Cohen, L. S., & Viguera, A. C. (2006). REPRODUCTIVE HEALTH AND BIPOLAR DISORDER. CNS SPECTRUMS, 11(5), 1–16. -
Effects of mood stabilizer treatment on mood episode relapse and recurrence in bipolar disorder
Ketter, T., Suppes, T., Goldberg, J., Frye, M., & White, R. (2004). Effects of mood stabilizer treatment on mood episode relapse and recurrence in bipolar disorder. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. CAMBRIDGE UNIV PRESS. -
The Texas implementation of medication algorithms: update to the algorithms for treatment of bipolar I disorder
Suppes, T., Dennehy, E. B., Hirschfeld, R. M., Altshuler, L. L., Bowden, C. L., Calabrese, … Swann, A. C. (2005). The Texas implementation of medication algorithms: update to the algorithms for treatment of bipolar I disorder. BIPOLAR DISORDERS. BLACKWELL PUBLISHING. -
Testing a clinical staging model for bipolar disorder using longitudinal life chart data.
van der Markt, A., Klumpers, U. M., Draisma, S., Dols, A., Nolen, W. A., Post, R. M., … Kupka, R. W. (2018). Testing a clinical staging model for bipolar disorder using longitudinal life chart data. Bipolar Disorders. -
More assortative mating in US compared to European parents and spouses of patients with bipolar disorder: implications for psychiatric illness in the offspring.
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2018). More assortative mating in US compared to European parents and spouses of patients with bipolar disorder: implications for psychiatric illness in the offspring. European Archives of Psychiatry and Clinical Neuroscience. -
Resting-State Functional Connectivity Dysfunction in Anhedonia as a Transdiagnostic Process: An RDoC Investigation
Samara, Z., Goldstein-Piekarski, A. N., Suppes, T., Yesavage, J., & Williams, L. (2016). Resting-State Functional Connectivity Dysfunction in Anhedonia as a Transdiagnostic Process: An RDoC Investigation. NEUROPSYCHOPHARMACOLOGY. NATURE PUBLISHING GROUP. -
Four Generations of US Patients Are More Ill than those from the Netherlands and Germany
Post, R. M., Leverich, G. S., Altshuler, L., Kupka, R., Keck, P., McElroy, S., … Nolen, W. A. (2016). Four Generations of US Patients Are More Ill than those from the Netherlands and Germany. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
Relationship Between Circadian Genes, Sleep, Rhythms, and Clinical Characteristics in Bipolar Disorder
Gonzalez, R., Gonzalez, S. D., Gupta, J., Mallawaarachchi, I., McClung, C., Tohen, M., … Suppes, T. (2016). Relationship Between Circadian Genes, Sleep, Rhythms, and Clinical Characteristics in Bipolar Disorder. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder
Riemann, G., Weisscher, N., Post, R. M., Altshuler, L., McElroy, S., Frye, M. A., … Kupka, R. W. (2017). The relationship between self-reported borderline personality features and prospective illness course in bipolar disorder. INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS, 5, 31. -
Florida Best Practice Psychotherapeutic Medication Guidelines for Adults With Major Depressive Disorder
McIntyre, R. S., Suppes, T., Tandon, R., & Ostacher, M. (2017). Florida Best Practice Psychotherapeutic Medication Guidelines for Adults With Major Depressive Disorder. JOURNAL OF CLINICAL PSYCHIATRY, 78(6), 703–13. -
Obesity and obstetric complications are associated with rapid-cycling in Italian patients with bipolar disorder
Caldiroli, A., Buoli, M., Dell'Osso, B., Carnevali, G. S., Serati, M., Suppes, T., … Altamura, A. C. (2017). Obesity and obstetric complications are associated with rapid-cycling in Italian patients with bipolar disorder. EUROPEAN PSYCHIATRY. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. -
Compared to Europeans, bipolar patients in the us have all the poor prognosis factors
Post, R., Altshuler, L., Kupka, R., Keck, P., McElroy, S., Frye, M., … Nolen, W. (2017). Compared to Europeans, bipolar patients in the us have all the poor prognosis factors. BIPOLAR DISORDERS. WILEY. -
User engagement within the moodswings 2.0 online self-guided intervention for bipolar disorder
Cosgrove, V., Gliddon, E., Berk, L., Lauder, S., Grimm, D., Dodd, S., … Berk, M. (2017). User engagement within the moodswings 2.0 online self-guided intervention for bipolar disorder. BIPOLAR DISORDERS. WILEY. -
Discussion forum engagement within an internet-based program for bipolar disorder: impacts on social support, stigma, quality of life and mood severity
Gliddon, E., Berk, L., Lauder, S., Cosgrove, V., Grimm, D., Dodd, S., … Berk, M. (2017). Discussion forum engagement within an internet-based program for bipolar disorder: impacts on social support, stigma, quality of life and mood severity. BIPOLAR DISORDERS. WILEY. -
Switch Rates During Acute Treatment for Bipolar II Depression With Lithium, Sertraline, or the Two Combined: A Randomized Double-Blind Comparison
Altshuler, L. L., Sugar, C. A., McElroy, S. L., Calimlim, B., Gitlin, M., Keck, P. E., … Suppes, T. (2017). Switch Rates During Acute Treatment for Bipolar II Depression With Lithium, Sertraline, or the Two Combined: A Randomized Double-Blind Comparison. AMERICAN JOURNAL OF PSYCHIATRY, 174(3), 266–76. -
More childhood onset bipolar disorder in the United States than Canada or Europe: Implications for treatment and prevention
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2017). More childhood onset bipolar disorder in the United States than Canada or Europe: Implications for treatment and prevention. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 74, 204–13. -
Increased Activity or Energy as a Primary Criterion for the Diagnosis of Bipolar Mania in DSM-5: Findings From the STEP-BD Study
Machado-Vieira, R., Luckenbaugh, D. A., Ballard, E. D., Henter, I. D., Tohen, M., Suppes, T., & Zarate, C. A. (2017). Increased Activity or Energy as a Primary Criterion for the Diagnosis of Bipolar Mania in DSM-5: Findings From the STEP-BD Study. AMERICAN JOURNAL OF PSYCHIATRY, 174(1), 70–76. -
Illnesses in siblings of US patients with bipolar disorder relate to multigenerational family history and patients severity of illness
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2017). Illnesses in siblings of US patients with bipolar disorder relate to multigenerational family history and patients severity of illness. JOURNAL OF AFFECTIVE DISORDERS, 207, 313–19. -
Age at Onset of Bipolar Disorder Related to Parental and Grandparental Illness Burden
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2016). Age at Onset of Bipolar Disorder Related to Parental and Grandparental Illness Burden. JOURNAL OF CLINICAL PSYCHIATRY, 77(10), E1309–E1315. -
Age of onset of bipolar disorder: Combined effect of childhood adversity and familial loading of psychiatric disorders
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2016). Age of onset of bipolar disorder: Combined effect of childhood adversity and familial loading of psychiatric disorders. JOURNAL OF PSYCHIATRIC RESEARCH, 81, 63–70. -
Further Evidence of a Cohort Effect in Bipolar Disorder: More Early Onsets and Family History of Psychiatric Illness in More Recent Epochs
Post, R. M., Kupka, R., Keck, P. E., McElroy, S. L., Altshuler, L. L., Frye, M. A., … Nolen, W. A. (2016). Further Evidence of a Cohort Effect in Bipolar Disorder: More Early Onsets and Family History of Psychiatric Illness in More Recent Epochs. JOURNAL OF CLINICAL PSYCHIATRY, 77(8), 1043–49. -
Stanley foundation bipolar network: predictors of psychosocial outcome
Bennett, F., Grunz, H., Close, A., Schaeerer, L., Suppes, T., Mintz, J., … Sharma, A. (2016). Stanley foundation bipolar network: predictors of psychosocial outcome. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Offspring of parents with bipolar illness from the US are more ill than those from the Netherlands and Germany
Post, R. M., Altshuler, L. L., Kupka, R. W., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2016). Offspring of parents with bipolar illness from the US are more ill than those from the Netherlands and Germany. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Is bipolar II response to treatment really the same as bipolar I disorder?
Suppes, T. (2016). Is bipolar II response to treatment really the same as bipolar I disorder? BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Lurasidone adjunctive with lithium or valproate for bipolar depression: A placebo-controlled trial utilizing prospective and retrospective enrolment cohorts
Suppes, T., Kroger, H., Pikalov, A., & Loebel, A. (2016). Lurasidone adjunctive with lithium or valproate for bipolar depression: A placebo-controlled trial utilizing prospective and retrospective enrolment cohorts. JOURNAL OF PSYCHIATRIC RESEARCH, 78, 86–93. -
Clinical correlates of sustained response to individual drugs used in naturalistic treatment of patients with bipolar disorder
Post, R. M., Leverich, G. S., Kupka, R., Keck, P. E., McElroy, S. L., Altshuler, L. L., … Nolen, W. A. (2016). Clinical correlates of sustained response to individual drugs used in naturalistic treatment of patients with bipolar disorder. COMPREHENSIVE PSYCHIATRY, 66, 146–56. -
Lurasidone for the Treatment of Major Depressive Disorder With Mixed Features: A Randomized, Double-Blind, Placebo-Controlled Study
Suppes, T., Silva, R., Cucchiaro, J., Mao, Y., Targum, S., Streicher, C., … Loebel, A. (2016). Lurasidone for the Treatment of Major Depressive Disorder With Mixed Features: A Randomized, Double-Blind, Placebo-Controlled Study. AMERICAN JOURNAL OF PSYCHIATRY, 173(4), 400–407. -
Weekly mood stability over 6 months with lamotrigine or placebo in bipolar rapid cycling
Goldberg, J. F., Malhotra, A. K., Calabrese, Bowden, C. L., Suppes, T., Frye, M. A., & Ketter, T. A. (2004). Weekly mood stability over 6 months with lamotrigine or placebo in bipolar rapid cycling. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
Reproductive and metabolic hormone levels in bipolar women
Altshuler, L. L., Rasgon, N. L., Elman, S., Bitran, J., Labarca, R., Saad, M., … Mintz, J. (2004). Reproductive and metabolic hormone levels in bipolar women. ACTA PSYCHIATRICA SCANDINAVICA. BLACKWELL PUBLISHING. -
A Brief Commentary on the Bipolar CHOICE Study
Suppes, T. (2016). A Brief Commentary on the Bipolar CHOICE Study. JOURNAL OF CLINICAL PSYCHIATRY, 77(1), E43–E44. -
Lurasidone for the treatment of major depressive disorder with mixed features: a randomised, double-blind, placebo-controlled 6 week trial
Suppes, T., Silva, R., Mao, Y., Cucchiaro, J., Streicher, C., Pikalov, A., & Loebel, A. (2015). Lurasidone for the treatment of major depressive disorder with mixed features: a randomised, double-blind, placebo-controlled 6 week trial. EUROPEAN NEUROPSYCHOPHARMACOLOGY. ELSEVIER SCIENCE BV. -
Towards diagnosis of depressive symptoms during manic episodes: the DSM-5 mixed specifier
Suppes, T. (2014). Towards diagnosis of depressive symptoms during manic episodes: the DSM-5 mixed specifier. EUROPEAN NEUROPSYCHOPHARMACOLOGY. ELSEVIER SCIENCE BV. -
Multigenerational Positive Family History of Psychiatric Disorders Is Associated With a Poor Prognosis in Bipolar Disorder
Post, R. M., Altshuler, L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2015). Multigenerational Positive Family History of Psychiatric Disorders Is Associated With a Poor Prognosis in Bipolar Disorder. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 27(4), 304–10. -
Predominant polarity in bipolar disorders: refining or redefining diagnosis?
Colom, F., Vieta, E., & Suppes, T. (2015). Predominant polarity in bipolar disorders: refining or redefining diagnosis? ACTA PSYCHIATRICA SCANDINAVICA, 132(5), 324–26. -
Ethical dilemmas of participant safety monitoring in online clinical research
Cosgrove, V., Grimm, D., Gliddon, E., Lauder, S., Dodd, S., Berk, M., & Suppes, T. (2015). Ethical dilemmas of participant safety monitoring in online clinical research. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Lurasidone for the treatment of major depressive disorder with mixed features: a randomized, double-blind, placebo-controlled 6 week trial
Suppes, T., Silva, R., Mao, Y., Cucchiaro, J., Streicher, C., & Loebel, A. (2015). Lurasidone for the treatment of major depressive disorder with mixed features: a randomized, double-blind, placebo-controlled 6 week trial. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Evidence for a cohort effect: a child network for assessing naturalistic treatment in the community
Post, R., Kupka, R., Keck, P., McElroy, S., Altshuler, L., Frye, M., … Findling, R. (2015). Evidence for a cohort effect: a child network for assessing naturalistic treatment in the community. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Implications and impressions of the ISBD Task Force DSM5 on mixed depression in bipolar disorder
Frye, M. A., Swann, A. C., Lafer, B., Perugi, G., Bauer, M., Bahk, W. M., … Suppes, T. (2015). Implications and impressions of the ISBD Task Force DSM5 on mixed depression in bipolar disorder. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Mixed depression in bipolar disorder: prevalence rate and clinical correlates during naturalistic follow up
Miller, S., Suppes, T., Mintz, J., Hellemann, G., Frye, M., McElroy, S., … Post, R. (2015). Mixed depression in bipolar disorder: prevalence rate and clinical correlates during naturalistic follow up. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Exploring inflammatory pathways in bipolar disorder
Suppes, T., Cosgrove, V., & Hallmayer, J. (2015). Exploring inflammatory pathways in bipolar disorder. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
LURASIDONE FOR MAJOR DEPRESSIVE DISORDER WITH MIXED FEATURES: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED 6 WEEK TRIAL
Loebel, A., Silva, R., Mao, Y., Cucchiaro, J., Streicher, C., & Suppes, T. (2015). LURASIDONE FOR MAJOR DEPRESSIVE DISORDER WITH MIXED FEATURES: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED 6 WEEK TRIAL. SCHIZOPHRENIA BULLETIN. OXFORD UNIV PRESS. -
The Impact of Antipsychotic Medications on Sleep-dependent Consolidation of Motor Procedural Memory in Subjects with Bipolar I Disorder
Ostacher, M., Stickgold, R., Iosifescu, D., Feldman, A., Grimm, D., Suppes, T., & Manoach, D. (2014). The Impact of Antipsychotic Medications on Sleep-dependent Consolidation of Motor Procedural Memory in Subjects with Bipolar I Disorder. NEUROPSYCHOPHARMACOLOGY. NATURE PUBLISHING GROUP. -
Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression (vol 121, pg 106, 2009)
Suppes, T., Datto, C., Minkwitz, M., Nordenhem, A., Walker, C., & Darko, D. (2014). Effectiveness of the extended release formulation of quetiapine as monotherapy for the treatment of acute bipolar depression (vol 121, pg 106, 2009). JOURNAL OF AFFECTIVE DISORDERS, 168, 484. -
Bipolar disorder is more virulent in the United States than many European countries
Post, R., Altshuler, L., Leverich, G., Nolen, W., Kupka, R., Grunze, H., … Rowe, M. (2014). Bipolar disorder is more virulent in the United States than many European countries. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. CAMBRIDGE UNIV PRESS. -
Mixed Depression in the Stanley Foundation Bipolar Treatment Network: Prevalence Rate and Clinical Correlates During Naturalistic Follow Up
Miller, S., Suppes, T., Hellemann, G., Frye, M., McElroy, S., Nolen, W., … Post, R. (2014). Mixed Depression in the Stanley Foundation Bipolar Treatment Network: Prevalence Rate and Clinical Correlates During Naturalistic Follow Up. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
Efficacy and safety of treatment with lurasidone adjunctive with lithium or valproate in bipolar I depression: results of two 6-week studies
Calabrese, J., Suppes, T., Sarma, K., Silva, R., Kroger, H., Cucchiaro, J., … Loebel, A. (2014). Efficacy and safety of treatment with lurasidone adjunctive with lithium or valproate in bipolar I depression: results of two 6-week studies. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Neuroimaging procedures and related acquisitions in bipolar disorder: state of the art
Dell'Osso, B., Dobrea, C., Palazzo, M. C., Cremaschi, L., Penzo, B., Benatti, B., … Altamura, A. C. (2014). Neuroimaging procedures and related acquisitions in bipolar disorder: state of the art. RIVISTA DI PSICHIATRIA, 49(1), 2–11. -
Maintenance treatment with quetiapine when combined with either lithium or divalproex in bipolar I disorder: analysis of 2 large randomized, placebo-controlled trials
Suppes, T., & Gustafsson, U. (2013). Maintenance treatment with quetiapine when combined with either lithium or divalproex in bipolar I disorder: analysis of 2 large randomized, placebo-controlled trials. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
How can mixed features be diagnosed and quantified, and what do they tell us about episodes of bipolar disorder?
Suppes, T. (2013). How can mixed features be diagnosed and quantified, and what do they tell us about episodes of bipolar disorder? BIPOLAR DISORDERS. WILEY-BLACKWELL. -
COMPARISON OF OBJECTIVE AND SUBJECTIVE ASSESSMENTS OF TOTAL SLEEP TIME IN BIPOLAR PATIENTS
Gonzalez, R., Gibbs, T., Tohen, M., & Suppes, T. (2012). COMPARISON OF OBJECTIVE AND SUBJECTIVE ASSESSMENTS OF TOTAL SLEEP TIME IN BIPOLAR PATIENTS. SLEEP. AMER ACAD SLEEP MEDICINE. -
The Effects of Manic and Depressive Symptoms on the Circadian Rhythmicity of Activity Levels in Bipolar Disorder
Gonzalez, R., Suppes, T., Tohen, M., & Tamminga, C. (2012). The Effects of Manic and Depressive Symptoms on the Circadian Rhythmicity of Activity Levels in Bipolar Disorder. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
The effects of manic and depressive symptoms on the circadian rhythmicity of activity levels in bipolar disorder
Gonzalez, R., Tohen, M., Tamminga, C., & Suppes, T. (2012). The effects of manic and depressive symptoms on the circadian rhythmicity of activity levels in bipolar disorder. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
MAINTENANCE TREATMENT WITH QUETIAPINE ADDED TO EITHER LITHIUM OR DIVALPROEX IN BIPOLAR I DISORDER
Suppes, T., Vieta, E., Gustafsson, U., & Paulsson, B. (2010). MAINTENANCE TREATMENT WITH QUETIAPINE ADDED TO EITHER LITHIUM OR DIVALPROEX IN BIPOLAR I DISORDER. EUROPEAN PSYCHIATRY. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. -
LONG-TERM EFFICACY OF QUETIAPINE IN COMBINATION WITH LITHIUM OR DIVALPROEX ON MIXED SYMPTOMS IN BIPOLAR I DISORDER
Vieta, E., Suppes, T., Gustafsson, U., & Paulsson, B. (2010). LONG-TERM EFFICACY OF QUETIAPINE IN COMBINATION WITH LITHIUM OR DIVALPROEX ON MIXED SYMPTOMS IN BIPOLAR I DISORDER. EUROPEAN PSYCHIATRY. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. -
The debate on duration criteria of hypomanic episodes: agreements, disagreements, and proposed solutions in DSM-5
Suppes, T. (2011). The debate on duration criteria of hypomanic episodes: agreements, disagreements, and proposed solutions in DSM-5. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Quetiapine in the maintenance treatment of bipolar I disorder: combined data from two long-term phase III studies
Olausson, B., Suppes, T., Vieta, E., Liu, S., Eriksson, H. A., & Paulsson, B. (2008). Quetiapine in the maintenance treatment of bipolar I disorder: combined data from two long-term phase III studies. INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. INFORMA HEALTHCARE. -
Efficacy and safety of quetiapine in combination with lithium/divalproex as maintenance treatment for bipolar I disorder (TRIAL 126)
Olausson, B., Vieta, E., Suppes, T., Eggens, I., Persson, I., & Bjorn, B. (2008). Efficacy and safety of quetiapine in combination with lithium/divalproex as maintenance treatment for bipolar I disorder (TRIAL 126). INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. INFORMA HEALTHCARE. -
Maintenance treatment in bipolar I disorder with quetiapine concomitant with lithium or divalproex: a North American placebo-controlled, randomized trial (TRIAL 127)
Olausson, B., Suppes, T., Vieta, E., Liu, S., & Paulsson, B. (2008). Maintenance treatment in bipolar I disorder with quetiapine concomitant with lithium or divalproex: a North American placebo-controlled, randomized trial (TRIAL 127). INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. INFORMA HEALTHCARE. -
Olanzapine and olanzapine-fluoxetine combination (OFC) in the treatment of bipolar depression
Tohen, M., Vieta, E., Kettter, T., Centorino, F., Calabrese, J., Sachs, G., … Breier, A. (2003). Olanzapine and olanzapine-fluoxetine combination (OFC) in the treatment of bipolar depression. JOURNAL OF PSYCHOPHARMACOLOGY. SAGE PUBLICATIONS LTD. -
Olanzapine versus divalproex sodium for bipolar mania: A 47-week study
Tohen, M., Baker, R. W., Altshuler, L., Zarate, C. A., Suppes, T., Ketter, T. A., … Gilmore, J. A. (2002). Olanzapine versus divalproex sodium for bipolar mania: A 47-week study. JOURNAL OF PSYCHOPHARMACOLOGY. SAGE PUBLICATIONS LTD. -
Olanzapine versus divalproex sodium for bipolar mania: a 47-week study
Tohen, M., Baker, R. W., Altshuler, L., Zarate, C. A., Suppes, T., Ketter, T. A., … Schuh, L. (2002). Olanzapine versus divalproex sodium for bipolar mania: a 47-week study. EUROPEAN PSYCHIATRY. EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. -
Increased risk factors and poor long-term outcome in the US compared to Holland and Germany
Post, R. M., Nolen, W. A., Kupka, R. W., Altshuler, L. L., Frye, M. A., Suppes, T., … Leverich, G. S. (2010). Increased risk factors and poor long-term outcome in the US compared to Holland and Germany. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Maintenance treatment with quetiapine added to either lithium or divalproex in bipolar I disorder
Suppes, T., Vieta, E., Gustafsson, U., & Paulsson, B. (2010). Maintenance treatment with quetiapine added to either lithium or divalproex in bipolar I disorder. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Long-term efficacy of quetiapine in combination with lithium or divalproex on mixed symptoms in bipolar I disorder
Vieta, E., Suppes, T., Gustafsson, U., & Paulsson, B. (2010). Long-term efficacy of quetiapine in combination with lithium or divalproex on mixed symptoms in bipolar I disorder. BIPOLAR DISORDERS. WILEY-BLACKWELL PUBLISHING, INC. -
The International Society for Bipolar Disorders (ISBD) Task Force on the Nomenclature of Course and Outcome in Bipolar Disorders
Tohen, M., Frank, E., Bowden, C. L., Colom, F., Ghaemi, N. S., Yatham, L. N., … Berk, M. (2010). The International Society for Bipolar Disorders (ISBD) Task Force on the Nomenclature of Course and Outcome in Bipolar Disorders. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Update from the Mood Disorders Workgroup, Bipolar Disorder Subcommittee
Suppes, T. (2010). Update from the Mood Disorders Workgroup, Bipolar Disorder Subcommittee. BIPOLAR DISORDERS. WILEY-BLACKWELL PUBLISHING, INC. -
Mixed depression in bipolar disorder: prevalence rate and clinical correlates during naturalistic follow up
Suppes, T., Hellemann, G., Frye, M. A., McElroy, S., Nolen, W., Kupka, R., … Grunze, H. (2010). Mixed depression in bipolar disorder: prevalence rate and clinical correlates during naturalistic follow up. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
The International Society for Bipolar Disorder (ISBD) work group on mixed states and treatment response
Frye, M. A., Suppes, T., & Swann, A. (2010). The International Society for Bipolar Disorder (ISBD) work group on mixed states and treatment response. BIPOLAR DISORDERS. WILEY. -
Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study
Tohen, M., Baker, R. W., Altshuler, L., Zarate, C. A., Suppes, T., Ketter, T. A., … Gilmore, J. A. (2002). Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
Long-term efficacy of Quetiapine in combination with Lithium or Divalproex on mixed symptoms in bipolar I disorder
Vieta, E., Suppes, T., Gustafsson, U., & Paulsson, P. (2009). Long-term efficacy of Quetiapine in combination with Lithium or Divalproex on mixed symptoms in bipolar I disorder. INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. TAYLOR & FRANCIS AS. -
Maintenance treatment with Quetiapine added to either Lithium or Divalproex in bipolar I disorder
Vieta, E., Suppes, T., Gustafsson, U., & Paulsson, B. (2009). Maintenance treatment with Quetiapine added to either Lithium or Divalproex in bipolar I disorder. INTERNATIONAL JOURNAL OF PSYCHIATRY IN CLINICAL PRACTICE. TAYLOR & FRANCIS AS. -
Maintenance treatment with quetiapine added to either lithium or divalproex in bipolar I disorder
Suppes, T., Vieta, E., Gustafsson, U., & Paulsson, B. (2009). Maintenance treatment with quetiapine added to either lithium or divalproex in bipolar I disorder. EUROPEAN NEUROPSYCHOPHARMACOLOGY. ELSEVIER SCIENCE BV. -
Mixed depression in bipolar disorder: prevalence rate and clinical correlates during naturalistic follow up
Suppes, T., Hellemann, G., Frye, M., McElroy, S., Nolen, W., Kupka, R., … Post, R. (2009). Mixed depression in bipolar disorder: prevalence rate and clinical correlates during naturalistic follow up. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
Factor analysis of bipolar mania: retrospectively-assessed structure of mixed mania from randomized clinical trial subjects
Swann, A. C., Suppes, T., Eudicone, J., Tran, Q. V., Pikalov, A., Owen, R., & Carlson, B. X. (2009). Factor analysis of bipolar mania: retrospectively-assessed structure of mixed mania from randomized clinical trial subjects. BIPOLAR DISORDERS. WILEY-BLACKWELL PUBLISHING, INC. -
Delay to first treatment is inversely related to age of onset of bipolar disorder and an independent contributor to a poor outcome in adulthood
Post, R. M., Leverich, G. S., Kupka, R., Keck, P., McElroy, S., Altshuler, L., … Nolen, W. A. (2009). Delay to first treatment is inversely related to age of onset of bipolar disorder and an independent contributor to a poor outcome in adulthood. BIPOLAR DISORDERS. WILEY-BLACKWELL PUBLISHING, INC. -
Prevalence rate of mixed depression and its impact on remission: a controlled evaluation
Frye, M., Hellemann, G., Suppes, T., McElroy, S., Grunze, H., Altshuler, L., … Post, R. (2009). Prevalence rate of mixed depression and its impact on remission: a controlled evaluation. BIPOLAR DISORDERS. WILEY-BLACKWELL. -
The genomics of treatment emergent mania: The Mayo Clinic Individualized Medicine Biobank for Bipolar Disorder
Biernacka, J., Veldic, M., McElroy, S. L., Crow, S., Sharp, A., Benitez, J., … Frye, M. A. (2009). The genomics of treatment emergent mania: The Mayo Clinic Individualized Medicine Biobank for Bipolar Disorder. BIPOLAR DISORDERS. WILEY-BLACKWELL PUBLISHING, INC. -
A one year randomized trial of clozapine vs usual care in bipolar I patients
Suppes, T., Rush, A. J., Webb, A., Carmody, T., & Kraemer, H. (1996). A one year randomized trial of clozapine vs usual care in bipolar I patients. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
A clinical model for identifying an inflammatory phenotype in mood disorders.
Kramer, N. E., Cosgrove, V. E., Dunlop, K., Subramaniapillai, M., McIntyre, R. S., & Suppes, T. (2019). A clinical model for identifying an inflammatory phenotype in mood disorders. Journal of Psychiatric Research, 113, 148–58. -
Post hoc analyses of asenapine treatment in pediatric patients with bipolar I disorder: efficacy related to mixed or manic episode, stage of illness, and body weight.
Findling, R. L., Earley, W., Suppes, T., Patel, M., Wu, X., Chang, C.-T. T., & McIntyre, R. S. (2018). Post hoc analyses of asenapine treatment in pediatric patients with bipolar I disorder: efficacy related to mixed or manic episode, stage of illness, and body weight. Neuropsychiatric Disease and Treatment, 14, 1941–1952. -
A randomized controlled trial of MoodSwings 2.0: An internet-based self-management program for bipolar disorder.
Gliddon, E., Cosgrove, V., Berk, L., Lauder, S., Mohebbi, M., Grimm, D., … Berk, M. (2019). A randomized controlled trial of MoodSwings 2.0: An internet-based self-management program for bipolar disorder. Bipolar Disorders, 21(1), 28–39. -
More illness in offspring of bipolar patients from the U.S. compared to Europe.
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2016). More illness in offspring of bipolar patients from the U.S. compared to Europe. Journal of Affective Disorders, 191, 180–6. -
Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition
Hidalgo-Mazzei, D., Berk, M., Cipriani, A., Cleare, A. J., Di Florio, A., Dietch, D., … Stokes, P. R. A. (2019). Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition. BRITISH JOURNAL OF PSYCHIATRY, 214(1), 27–35. -
Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study
Tohen, M., Ketter, T. A., Zarate, C. A., Suppes, T., Frye, M., Altshuler, L., … Baker, R. W. (2003). Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study. JOURNAL OF PSYCHOPHARMACOLOGY. SAGE PUBLICATIONS LTD. -
Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression: A Randomized Clinical Trial.
McIntyre, R. S., Subramaniapillai, M., Lee, Y., Pan, Z., Carmona, N. E., Shekotikhina, M., … Mansur, R. B. (2019). Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression: A Randomized Clinical Trial. JAMA Psychiatry. -
Depression With Mixed Features in Major Depressive Disorder: A New Diagnosis or There All Along?
Ostacher, M. J., & Suppes, T. (2018). Depression With Mixed Features in Major Depressive Disorder: A New Diagnosis or There All Along? JOURNAL OF CLINICAL PSYCHIATRY, 79(2), 94–95. -
A clinical model for identifying an inflammatory phenotype in mood disorders
Kramer, N. E., Cosgrove, V. E., Dunlap, K., Subramaniapillai, M., McIntyre, R. S., & Suppes, T. (2019). A clinical model for identifying an inflammatory phenotype in mood disorders. JOURNAL OF PSYCHIATRIC RESEARCH, 113, 148–58. -
Testing a clinical staging model for bipolar disorder using longitudinal life chart data
van der Markt, A., Klumpers, U. M. H., Draisma, S., Dols, A., Nolen, W. A., Post, R. M., … Kupka, R. W. (2019). Testing a clinical staging model for bipolar disorder using longitudinal life chart data. BIPOLAR DISORDERS, 21(3), 228–34. -
A SYSTEMATIC REVIEW OF PSILOCYBIN IN THE TREATMENT OF DEPRESSION AND ANXIETY
Lyu, J., Hambro, B., & Suppes, T. (2019). A SYSTEMATIC REVIEW OF PSILOCYBIN IN THE TREATMENT OF DEPRESSION AND ANXIETY. JOURNAL OF AFFECTIVE DISORDERS. ELSEVIER SCIENCE BV. -
Quetiapine for the treatment of bipolar II depression
Suppes, T., Vieta, E., Raines, S., & Macfadden, W. (2005). Quetiapine for the treatment of bipolar II depression. BIPOLAR DISORDERS. BLACKWELL PUBLISHING. -
Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression: A Randomized Clinical Trial
McIntyre, R. S., Subramaniapillai, M., Lee, Y., Pan, Z., Carmona, N. E., Shekotikhina, M., … Mansur, R. B. (2019). Efficacy of Adjunctive Infliximab vs Placebo in the Treatment of Adults With Bipolar I/II Depression: A Randomized Clinical Trial. JAMA PSYCHIATRY, 76(8), 783–90. -
Adding Increased Energy or Activity to Criterion (A) of the DSM-5 Definition of Hypomania and Mania: Effect on the Diagnoses of 907 Patients From the Bipolar Collaborative Network.
Fredskild, M. U., Mintz, J., Frye, M. A., McElroy, S. L., Nolen, W. A., Kupka, R., … Suppes, T. (2019). Adding Increased Energy or Activity to Criterion (A) of the DSM-5 Definition of Hypomania and Mania: Effect on the Diagnoses of 907 Patients From the Bipolar Collaborative Network. The Journal of Clinical Psychiatry, 80(6). -
Efficacy and safety of cariprazine in bipolar I depression: A double-blind, placebo-controlled phase 3 study.
Earley, W. R., Burgess, M. V., Khan, B., Rekeda, L., Suppes, T., Tohen, M., & Calabrese, J. R. (2019). Efficacy and safety of cariprazine in bipolar I depression: A double-blind, placebo-controlled phase 3 study. Bipolar Disorders. -
Cariprazine efficacy in bipolar I depression with and without concurrent manic symptoms: post hoc analysis of 3 randomized, placebo-controlled studies.
McIntyre, R. S., Suppes, T., Earley, W., Patel, M., & Stahl, S. M. (2019). Cariprazine efficacy in bipolar I depression with and without concurrent manic symptoms: post hoc analysis of 3 randomized, placebo-controlled studies. CNS Spectrums, 1–9. -
Efficacy of lurasidone in major depression with mixed features: Pattern of improvement in depressive and manic symptoms
Nierenberg, A. A., Tsai, J., Mao, Y., Pikalov, A., Suppes, T., & Loebel, A. (2016). Efficacy of lurasidone in major depression with mixed features: Pattern of improvement in depressive and manic symptoms. EUROPEAN PSYCHIATRY. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. -
Predictors of psychosocial outcome of bipolar disorder: data from the Stanley Foundation Bipolar Network
Bennett, F., Hodgetts, S., Close, A., Frye, M., Grunze, H., Keck, P., … Sharma, A. N. (2019). Predictors of psychosocial outcome of bipolar disorder: data from the Stanley Foundation Bipolar Network. INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS, 7(1), 28. -
A pooled post hoc analysis evaluating the safety and tolerability of cariprazine in bipolar depression.
Earley, W. R., Burgess, M., Rekeda, L., Hankinson, A., McIntyre, R. S., Suppes, T., … Yatham, L. N. (2019). A pooled post hoc analysis evaluating the safety and tolerability of cariprazine in bipolar depression. Journal of Affective Disorders, 263, 386–95. -
Evidence-Based Treatment Targets, Selection, and Strategies for Acute Manic and Mixed Episodes of Bipolar I Disorder.
Suppes, T. (2019). Evidence-Based Treatment Targets, Selection, and Strategies for Acute Manic and Mixed Episodes of Bipolar I Disorder. The Journal of Clinical Psychiatry, 81(1). -
Strategies for Shifting From Acute to Maintenance Treatment for Bipolar I Disorder.
Suppes, T. (2020). Strategies for Shifting From Acute to Maintenance Treatment for Bipolar I Disorder. The Journal of Clinical Psychiatry, 81(1). -
More assortative mating in US compared to European parents and spouses of patients with bipolar disorder: implications for psychiatric illness in the offspring
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2020). More assortative mating in US compared to European parents and spouses of patients with bipolar disorder: implications for psychiatric illness in the offspring. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE, 270(2), 237–45. -
Extracellular Vesicle Biomarkers Reveal Inhibition of Neuroinflammation by Infliximab in Association with Antidepressant Response in Adults with Bipolar Depression.
Mansur, R. B., Delgado-Peraza, F., Subramaniapillai, M., Lee, Y., Iacobucci, M., Rodrigues, N., … Kapogiannis, D. (2020). Extracellular Vesicle Biomarkers Reveal Inhibition of Neuroinflammation by Infliximab in Association with Antidepressant Response in Adults with Bipolar Depression. Cells, 9(4). -
Efficacy of Adjunctive Infliximab vs. Placebo in the Treatment of Anhedonia in Bipolar I/II Depression.
Lee, Y., Mansur, R. B., Brietzke, E., Carmona, N. E., Subramaniapillai, M., Pan, Z., … McIntyre, R. S. (2020). Efficacy of Adjunctive Infliximab vs. Placebo in the Treatment of Anhedonia in Bipolar I/II Depression. Brain, Behavior, and Immunity. -
The Effectiveness of Ketamine on Anxiety, Irritability, and Agitation: Implications for Treating Mixed Features in Adults with Major Depressive or Bipolar Disorder.
McIntyre, R. S., Lipsitz, O., Rodrigues, N. B., Lee, Y., Cha, D. S., Vinberg, M., … Rosenblat, J. D. (2020). The Effectiveness of Ketamine on Anxiety, Irritability, and Agitation: Implications for Treating Mixed Features in Adults with Major Depressive or Bipolar Disorder. Bipolar Disorders. -
Treatment with infliximab augments neuronal insulin signaling in adults with bipolar depression
Mansur, R., Delgado-Peraza, F., Subramaniapillai, M., Lee, Y., Iacobucci, M., Nasri, F., … McIntyre, R. (2020). Treatment with infliximab augments neuronal insulin signaling in adults with bipolar depression. BIPOLAR DISORDERS, 22, 51. -
Leptin mediates improvements in cognitive function following treatment with infliximab in adults with bipolar depression.
Mansur, R. B., Subramaniapillai, M., Lee, Y., Pan, Z., Carmona, N. E., Shekotikhina, M., … McIntyre, R. S. (2020). Leptin mediates improvements in cognitive function following treatment with infliximab in adults with bipolar depression. Psychoneuroendocrinology, 120, 104779. -
Attitudes on pharmacogenetic testing in psychiatric patients with treatment-resistant depression
McCarthy, M. J., Chen, Y., Demodena, A., Fisher, E., Golshan, S., Suppes, T., & Kelsoe, J. R. (2020). Attitudes on pharmacogenetic testing in psychiatric patients with treatment-resistant depression. DEPRESSION AND ANXIETY. -
Relationship of comorbid personality disorders to prospective outcome in bipolar disorder.
Post, R. M., Leverich, G. S., McElroy, S., Kupka, R., Suppes, T., Altshuler, L., … Rowe, M. (2020). Relationship of comorbid personality disorders to prospective outcome in bipolar disorder. Journal of Affective Disorders, 276, 147–51. -
Double jeopardy in the United States: Early onset bipolar disorder and treatment delay.
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., … Nolen, W. A. (2020). Double jeopardy in the United States: Early onset bipolar disorder and treatment delay. Psychiatry Research, 292, 113274. -
A Neglected Condition
Swartz, H. A., & Suppes, T. (2019). A Neglected Condition. BIPOLAR II DISORDER: RECOGNITION, UNDERSTANDING, AND TREATMENT, 3–16. -
Diagnosing Bipolar II Disorder
Kramer, N., & Suppes, T. (2019). Diagnosing Bipolar II Disorder. BIPOLAR II DISORDER: RECOGNITION, UNDERSTANDING, AND TREATMENT, 17–50. -
Bipolar and Related Disorders
Miller, S., Ostacher, M., & Suppes, T. (2019). Bipolar and Related Disorders. AMERICAN PSYCHIATRIC ASSOCIATION PUBLISHING TEXTBOOK OF PSYCHIATRY, 7TH EDITION, 279–306. -
A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don't work well enough?
Dodd, S., Bauer, M., Carvalho, A. F., Eyre, H., Fava, M., Kasper, S., … Berk, M. (2020). A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don't work well enough? The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry, 1–20. -
Effects of infliximab on brain neurochemistry of adults with bipolar depression.
Mansur, R. B., Subramaniapillai, M., Lee, Y., Pan, Z., Carmona, N. E., Shekotikhina, M., … McIntyre, R. S. (2020). Effects of infliximab on brain neurochemistry of adults with bipolar depression. Journal of Affective Disorders, 281, 61–66. -
Exploring brain insulin resistance in adults with bipolar depression using extracellular vesicles of neuronal origin.
Mansur, R. B., Delgado-Peraza, F., Subramaniapillai, M., Lee, Y., Iacobucci, M., Nasri, F., … McIntyre, R. S. (2020). Exploring brain insulin resistance in adults with bipolar depression using extracellular vesicles of neuronal origin. Journal of Psychiatric Research, 133, 82–92. -
The factor structure of depressive symptoms in patients with obesity enrolled in the RAINBOW clinical trial.
Majd, M., Smyth, J. M., Lv, N., Xiao, L., Snowden, M. B., Venditti, E. M., … Ma, J. (2020). The factor structure of depressive symptoms in patients with obesity enrolled in the RAINBOW clinical trial. Journal of Affective Disorders, 281, 367–75. -
Strategies for Shifting From Acute to Maintenance Treatment for Bipolar I Disorder
Suppes, T. (2020). Strategies for Shifting From Acute to Maintenance Treatment for Bipolar I Disorder. JOURNAL OF CLINICAL PSYCHIATRY, 81(1). -
Evidence-Based Treatment Targets, Selection, and Strategies for Acute Manic and Mixed Episodes of Bipolar I Disorder
Suppes, T. (2020). Evidence-Based Treatment Targets, Selection, and Strategies for Acute Manic and Mixed Episodes of Bipolar I Disorder. JOURNAL OF CLINICAL PSYCHIATRY, 81(1). -
Peripheral inflammatory biomarkers define biotypes of bipolar depression.
Lee, Y., Mansur, R. B., Brietzke, E., Kapogiannis, D., Delgado-Peraza, F., Boutilier, J. J., … McIntyre, R. S. (2021). Peripheral inflammatory biomarkers define biotypes of bipolar depression. Molecular Psychiatry. -
25 Years of the International Bipolar Collaborative Network (BCN).
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Grunze, H., … Nolen, W. A. (2021). 25 Years of the International Bipolar Collaborative Network (BCN). International Journal of Bipolar Disorders, 9(1), 13. -
A prospective study to determine the clinical utility of pharmacogenetic testing of veterans with treatment-resistant depression.
McCarthy, M. J., Chen, Y., Demodena, A., Leckband, S. G., Fischer, E., Golshan, S., … Kelsoe, J. R. (2021). A prospective study to determine the clinical utility of pharmacogenetic testing of veterans with treatment-resistant depression. Journal of Psychopharmacology (Oxford, England), 2698811211015224. -
Impact of modification to DSM-5 criterion A for hypomania/mania in newly diagnosed bipolar patients: findings from the prospective BIO study.
Fredskild, M. U., Stanislaus, S., Coello, K., Melbye, S. A., Kjarstad, H. L., Sletved, K. S., … Kessing, L. V. (2021). Impact of modification to DSM-5 criterion A for hypomania/mania in newly diagnosed bipolar patients: findings from the prospective BIO study. International Journal of Bipolar Disorders, 9(1), 14. -
Early changes in neural circuit function engaged by negative emotion and modified by behavioural intervention are associated with depression and problem-solving outcomes: A report from the ENGAGE randomized controlled trial.
Goldstein-Piekarski, A. N., Wielgosz, J., Xiao, L., Stetz, P., Correa, C. G., Chang, S. E., … Williams, L. M. (2021). Early changes in neural circuit function engaged by negative emotion and modified by behavioural intervention are associated with depression and problem-solving outcomes: A report from the ENGAGE randomized controlled trial. EBioMedicine, 67, 103387. -
Investigation of a Capnometry Guided Respiratory Intervention in the Treatment of Posttraumatic Stress Disorder.
Ostacher, M. J., Fischer, E., Bowen, E. R., Lyu, J., Robbins, D. J., & Suppes, T. (2021). Investigation of a Capnometry Guided Respiratory Intervention in the Treatment of Posttraumatic Stress Disorder. Applied Psychophysiology and Biofeedback. -
Problem-solving therapy-induced amygdala engagement mediates lifestyle behavior change in obesity with comorbid depression: a randomized proof-of-mechanism trial.
Lv, N., Lefferts, W. K., Xiao, L., Goldstein-Piekarski, A. N., Wielgosz, J., Lavori, P. W., … Ma, J. (2021). Problem-solving therapy-induced amygdala engagement mediates lifestyle behavior change in obesity with comorbid depression: a randomized proof-of-mechanism trial. The American Journal of Clinical Nutrition. -
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) recommendations for the management of patients with bipolar disorder with mixed presentations.
Yatham, L. N., Chakrabarty, T., Bond, D. J., Schaffer, A., Beaulieu, S., Parikh, S. V., … Post, R. (2021). Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) recommendations for the management of patients with bipolar disorder with mixed presentations. Bipolar Disorders. -
Prevalence of impaired kidney function in patients with long-term lithium-treatment: a systematic review and meta-analysis.
Schoretsanitis, G., de Filippis, R., Brady, B. M., Homan, P., Suppes, T., & Kane, J. M. (2021). Prevalence of impaired kidney function in patients with long-term lithium-treatment: a systematic review and meta-analysis. Bipolar Disorders. -
Lithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder: A Randomized Clinical Trial.
Katz, I. R., Rogers, M. P., Lew, R., Thwin, S. S., Doros, G., Ahearn, E., … Liang, M. H. (2021). Lithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder: A Randomized Clinical Trial. JAMA Psychiatry. -
Mania and bipolar depression: complementing not opposing poles-a post-hoc analysis of mixed features in manic and hypomanic episodes
Born, C., Grunze, H., Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., … Schaerer, L. (2021). Mania and bipolar depression: complementing not opposing poles-a post-hoc analysis of mixed features in manic and hypomanic episodes. INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS, 9(1), 36. -
Chronbiologically-based sub-groups in bipolar I disorder: A latent profile analysis.
Gonzalez, R., Dwivedi, A., Zeitzer, J., Suppes, T., Tohen, M., Forero, A., & Alvarado, A. (2021). Chronbiologically-based sub-groups in bipolar I disorder: A latent profile analysis. Journal of Affective Disorders. -
Repetitive Transcranial Magnetic Stimulation as a Treatment for Veterans with Cognitive Impairment and Multiple Comorbidities.
Cheng, J., Fairchild, J. K., McNerney, M. W., Noda, A., Ashford, J. W., Suppes, P., … Yesavage, J. (1800). Repetitive Transcranial Magnetic Stimulation as a Treatment for Veterans with Cognitive Impairment and Multiple Comorbidities. Journal of Alzheimer's Disease : JAD. -
A pilot trial of quetiapine, lithium, or placebo added to divalproex sodium for hypomanic or manic episodes in ambulatory adults with bipolar I disorder.
Cosgrove, V. E., Allende, S., Gwizdowski, I., Grace Fischer, E., Ostacher, M., & Suppes, T. (2022). A pilot trial of quetiapine, lithium, or placebo added to divalproex sodium for hypomanic or manic episodes in ambulatory adults with bipolar I disorder. International Journal of Bipolar Disorders, 10(1), 7. -
Are personality disorders in bipolar patients more frequent in the US than Europe?
Post, R. M., Leverich, G. S., McElroy, S. L., Kupka, R., Suppes, T., Altshuler, L. L., … Rowe, M. (2022). Are personality disorders in bipolar patients more frequent in the US than Europe? European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, 58, 47–54. -
Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial.
Oslin, D. W., Lynch, K. G., Shih, M.-C., Ingram, E. P., Wray, L. O., Chapman, S. R., … Wood, A. E. (2022). Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial. JAMA, 328(2), 151–161. -
The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management.
McIntyre, R. S., Alda, M., Baldessarini, R. J., Bauer, M., Berk, M., Correll, C. U., … Maj, M. (2022). The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management. World Psychiatry : Official Journal of the World Psychiatric Association (WPA), 21(3), 364–387. -
Cost-Utility and Cost-effectiveness of MoodSwings 2.0, an Internet-Based Self-management Program for Bipolar Disorder: Economic Evaluation Alongside a Randomized Controlled Trial.
Chatterton, M. L., Lee, Y. Y., Berk, L., Mohebbi, M., Berk, M., Suppes, T., … Mihalopoulos, C. (2022). Cost-Utility and Cost-effectiveness of MoodSwings 2.0, an Internet-Based Self-management Program for Bipolar Disorder: Economic Evaluation Alongside a Randomized Controlled Trial. JMIR Mental Health, 9(11), e36496. -
Novel and emerging treatments for major depression.
Marwaha, S., Palmer, E., Suppes, T., Cons, E., Young, A. H., & Upthegrove, R. (2022). Novel and emerging treatments for major depression. Lancet (London, England). -
Adjunctive Lumateperone (ITI-007) in the Treatment of Bipolar Depression: Results From a Randomized Placebo-Controlled Clinical Trial.
Suppes, T., Durgam, S., Kozauer, S. G., Chen, R., Lakkis, H. D., Davis, R. E., … Tohen, M. (2023). Adjunctive Lumateperone (ITI-007) in the Treatment of Bipolar Depression: Results From a Randomized Placebo-Controlled Clinical Trial. Bipolar Disorders. -
Psychologists' and psychotherapists' knowledge, attitudes, and clinical practices regarding the therapeutic use of psychedelics.
Kucsera, A., Suppes, T., & Haug, N. A. (2023). Psychologists' and psychotherapists' knowledge, attitudes, and clinical practices regarding the therapeutic use of psychedelics. Clinical Psychology & Psychotherapy. -
Mediating Effects of Neural Targets on Depression, Weight, and Anxiety Outcomes of an Integrated Collaborative Care Intervention: The ENGAGE-2 Mechanistic Pilot Randomized Clinical Trial.
Lv, N., Ajilore, O. A., Xiao, L., Venditti, E. M., Lavori, P. W., Gerber, B. S., … Ma, J. (2023). Mediating Effects of Neural Targets on Depression, Weight, and Anxiety Outcomes of an Integrated Collaborative Care Intervention: The ENGAGE-2 Mechanistic Pilot Randomized Clinical Trial. Biological Psychiatry Global Open Science, 3(3), 430–442. -
Treatments for major depression Reply
Marwaha, S., Young, A. H., Suppes, T., & Upthegrove, R. (2023). Treatments for major depression Reply. LANCET, 401(10394), 2111–2112. -
Acute Effects of MDMA on Intrinsic Functional Connectomes Associated With Altered States of Consciousness and Defensiveness
Zhang, X., Hack, L., Heifets, B., Suppes, T., van Roessel, P., Yesavage, J., … Williams, L. (2023). Acute Effects of MDMA on Intrinsic Functional Connectomes Associated With Altered States of Consciousness and Defensiveness. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
Acute Effects of MDMA on Negative Affective Brain Circuit Function: A Randomized Controlled Mechanistic Trial
Hack, L., Zhang, X., Heifets, B., Suppes, T., van Roessel, P., Yesavage, J., … Williams, L. (2023). Acute Effects of MDMA on Negative Affective Brain Circuit Function: A Randomized Controlled Mechanistic Trial. BIOLOGICAL PSYCHIATRY. ELSEVIER SCIENCE INC. -
A double-blind, randomized, placebo-controlled plus open trial of adjunctive suvorexant for treatment-resistant insomnia in patients with bipolar disorder
Cafaro, R., Macellaro, M., Suppes, T., Dell'Osso, B., Ketter, T., Miller, S., … Wang, P. (2023). A double-blind, randomized, placebo-controlled plus open trial of adjunctive suvorexant for treatment-resistant insomnia in patients with bipolar disorder. BIPOLAR DISORDERS. WILEY. -
Ketamine's acute effects on negative brain states are mediated through distinct altered states of consciousness in humans.
Hack, L. M., Zhang, X., Heifets, B. D., Suppes, T., van Roessel, P. J., Yesavage, J. A., … Williams, L. M. (2023). Ketamine's acute effects on negative brain states are mediated through distinct altered states of consciousness in humans. Nature Communications, 14(1), 6631. -
Mixed Features in Bipolar Disorder: assessing symptoms profiles and their relation with DSM-5 criteria
Cafaro, R., Macellaro, M., Dell'Osso, B., & Suppes, T. (2023). Mixed Features in Bipolar Disorder: assessing symptoms profiles and their relation with DSM-5 criteria. EUROPEAN PSYCHIATRY. CAMBRIDGE UNIV PRESS. -
Mixed States and Suicidality in Bipolar Disorder: Results from the Stanley Foundation Bipolar Treatment Network
Macellaro, M., Cafaro, R., Dell'Osso, B., & Suppes, T. (2023). Mixed States and Suicidality in Bipolar Disorder: Results from the Stanley Foundation Bipolar Treatment Network. EUROPEAN PSYCHIATRY. CAMBRIDGE UNIV PRESS. -
Updates in the Assessment and Management of Bipolar Disorder.
Suppes, T. (2023). Updates in the Assessment and Management of Bipolar Disorder. Focus (American Psychiatric Publishing), 21(4), 343. -
Bipolar II Disorder: Understudied and Underdiagnosed.
Swartz, H. A., & Suppes, T. (2023). Bipolar II Disorder: Understudied and Underdiagnosed. Focus (American Psychiatric Publishing), 21(4), 354–362. -
Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months.
Zhang, X., Pines, A., Stetz, P., Goldstein-Piekarski, A. N., Xiao, L., Lv, N., … Williams, L. M. (2024). Adaptive cognitive control circuit changes associated with problem-solving ability and depression symptom outcomes over 24 months. Science Translational Medicine, 16(763), eadh3172. -
Psychiatry and nephrology partnering to improve quality of care.
Brady, B., & Suppes, T. (2024). Psychiatry and nephrology partnering to improve quality of care. The Lancet. Psychiatry, 11(12), 948–949.
-
Lamotrigine for the treatment of bipolar disorder: a clinical case series
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- PRIME Care (PRecision Medicine In MEntal Health Care)
- Acute Treatment of Bipolar II Depression
- Internet-Based Interventions for Bipolar Disorder
- VA Augmentation and Switching Treatments for Improving Depression Outcomes
- 12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depression
- An Open Label Study of the Safety and Efficacy of Psilocybin in Participants With Treatment-Resistant Depression (P-TRD)
Practice Locations
,
,
Important Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Referring Physicians
PHYSICIAN HELPLINE
Fax: 650-320-9443
Monday–Friday, 8 a.m.–5 p.m.
Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referral Information.
You may also submit a web referral or complete a referral form and fax it to 650-320-9443 or email the Referral Center at ReferralCenter@stanfordhealthcare.org.
- Send referrals online
- Place radiology and lab orders
- View referral status
- Access medical records