Rahul P Sharma, MBBS, FRACP
Cardiologist, Interventional cardiologist
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
Bio:
Dr Rahul P. Sharma, MBBS, FRACP is the Director of Structural Interventions at Stanford Healthcare and Clinical Assistant Professor of Medicine at Stanford University.
Dr Sharma graduated from Monash University and completed his medicine and cardiology training at the Alfred Hospital in Melbourne, Australia. He completed an advanced interventional and structural fellowship at Cedars Sinai Medical Center in Los Angeles, California in 2015 before joining Cedars Sinai as Clinical Faculty, Director of the Structural Imaging Core Laboratory and Associate Director of Interventional Cardiology Research until 2019, before joining Stanford Healthcare.
Dr Sharma is an Interventional Cardiologist with specialized clinical and research interests in structural heart disease, particularly transcatheter valve therapy. He has a large volume of expertise in transcatheter aortic, mitral and tricuspid replacement, percutaneous mitral valve repair, left atrial appendage occlusion, PFO/ASD/VSD closure, alcohol septal ablation and cerebral protection. He also has expertise in CT imaging for structural heart disease. He is a clinical investigator in ongoing national multi-center research studies and clinical trials and has co-authored numerous peer reviewed, scientific articles and book chapters. Dr Sharma also serves as a national and international clinical proctor for transcatheter aortic and mitral valve implantation and percutaneous mitral valve repair and speaks regularly at major national and international cardiology meetings.
Dr Sharma graduated from Monash University and completed his medicine and cardiology training at the Alfred Hospital in Melbourne, Australia. He completed an advanced interventional and structural fellowship at Cedars Sinai Medical Center in Los Angeles, California in 2015 before joining Cedars Sinai as Clinical Faculty, Director of the Structural Imaging Core Laboratory and Associate Director of Interventional Cardiology Research until 2019, before joining Stanford Healthcare.
Dr Sharma is an Interventional Cardiologist with specialized clinical and research interests in structural heart disease, particularly transcatheter valve therapy. He has a large volume of expertise in transcatheter aortic, mitral and tricuspid replacement, percutaneous mitral valve repair, left atrial appendage occlusion, PFO/ASD/VSD closure, alcohol septal ablation and cerebral protection. He also has expertise in CT imaging for structural heart disease. He is a clinical investigator in ongoing national multi-center research studies and clinical trials and has co-authored numerous peer reviewed, scientific articles and book chapters. Dr Sharma also serves as a national and international clinical proctor for transcatheter aortic and mitral valve implantation and percutaneous mitral valve repair and speaks regularly at major national and international cardiology meetings.
Practice Areas
- Alcohol Septal Ablation
- Aortic Stenosis
- Atherosclerosis
- Atrial Fibrillation (AFib)
- Atrial Septal Defect Closure
- Balloon aortic valvuloplasty
- Balloon Dilation
- Balloon mitral valvuloplasty
- Balloon Valvuloplasty
- Bicuspid Aortic Valve
- Cardiac Catheterization
- Cerebral Protection
- Computed Tomography Scan (CT Scan)
- Coronary Angiogram
- Coronary Artery Disease
- Coronary artery stent
- Echocardiogram
- Electrocardiogram (EKG)
- Heart Attack
- Heart Valve Disease
- Heart Valve Repair or Replacement
- Hybrid Coronary Revascularization
- Hypertrophic Cardiomyopathy
- Intravascular Ultrasound (IVUS)
- Left Atrial Appendage Closure
- Mitral Valve Prolapse
- Mitral Valve Stenosis and Regurgitation
- Obstructive Coronary Artery Disease
- Optical Coherence Tomography (OCT)
- Percutaneous Coronary Intervention
- Perivalvular Leak Closure
- Right Heart Catheterization
- Transcatheter Aortic Valve Implantation (TAVI)
- Transcatheter Aortic Valve Replacement (TAVR)
- Transcatheter Mitral Valve Repair (TMVR)
- Transcatheter Tricuspid Valve Repair
- Transcatheter Tricuspid Valve Replacement
Professional Education
- Board Certification: Royal Australasian College of Physicians - Australia, Cardiology (2013)
- Fellowship, Cedars Sinai Medical Center, Interventional and Structural Cardiology, Los Angeles, CA (2015)
- Fellowship, Alfred Hospital, Cardiology Advanced Physician Training, Melbourne, Australia (2014)
- Fellowship, Monash Medical Center, Melbourne, Australia (2014)
- Fellowship, Royal Australasian College of Surgeons, Alfred Health, Melbourne, Australia (2013)
- Residency, Alfred Hospital, General Medicine, Melbourne, Australia (2011)
- Internship, Alfred Hospital, Melbourne, Australia (2011)
- MBBS, Monash University, Bachelor of Medicine, Bachelor of Surgery, Melbourne, Australia (2006)
Honors & Awards
- Excellence in Teaching Award 2017-2018, Cedars Sinai Medical Center (2018)
- Finalist – Alfred Health Research Prize, - (2011)
- Finalist – Australian and New Zealand Society for Geriatric Medicine Prize, - (2006)
- Finalist – Prince Henry’s Institute Surgical Prize, - (2006)
- Finalist – Royal Australian College of Physicians Research Prize, - (2012)
- No. 1 ranked candidate overall for entrance to Cardiology Fellowship, - (2011)
- Recipient of Academic Scholarship for Masters in Health Delivery Sciences, - (2018)
- Winner – “Medtech’s Got Talent” Innovation Award, - (2014)
- Winner – Alfred Health Senior Medical Staff Research Scholarship, - (2012)
- Winner – Alfred Health Teacher of the Year Award, - (2011)
- Winner – Alfred Health Teacher of the Year Award, - (2012)
- Winner – Alfred Health Teaching Supervisors Award, - (2010)
- Winner – Anglican Church Grammar School Old Boy’s Association Scholarship, - (2012)
- Winner – Baker IDI research travel scholarship, - (2007)
- Winner – Monash University Medical Students Teaching Award, - (2011)
- Winner – Monash University overseas elective scholarship, - (2006)
- Winner – Novartis research travel scholarship, - (2009)
- Winner – Victoria Cardiology Registrar’s Research Prize, Cardiac Society of Australia and New Zealand (2011)
Administrative Appointments
- Affiliate Member, Cardiac Society of Australia and New Zealand (2014 - Present)
- Clinical Assistant Professor, Stanford University (2019 - Present)
- Director of Structural Interventions, Stanford Healthcare (2019 - Present)
- Fellow, Royal Australasian College of Physicians (2012 - Present)
- Founder and President, Association of Victorian Cardiology Advanced Trainees, Australia (2011 - 2014)
- Interventional Cardiologist, Cedars-Sinai Medical Center (2017 - 2019)
- Interventional Cardiologist, Stanford Health Care (2019 - Present)
- Representative, Royal Australasian College of Physicians Victorian and Tasmanian Training Committee, Australia (2011 - 2016)
- Research Scientist II, Department of Medicine, Cedars Sinai Medical Center (2016 - 2017)
Publications
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Randomized double-blind placebo-controlled crossover study to determine the effects of esomeprazole on inhibition of platelet function by clopidogrel
Fernando, H., Bassler, N., Habersberger, J., Sheffield, L. J., Sharma, R., Dart, A. M., … Shaw, J. A. (2011). Randomized double-blind placebo-controlled crossover study to determine the effects of esomeprazole on inhibition of platelet function by clopidogrel. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 9(8), 1582–89. -
Transcatheter Mitral Valve Replacement for Degenerated Bioprosthetic Valves and Failed Annuloplasty Rings.
Yoon, S.-H. H., Whisenant, B. K., Bleiziffer, S., Delgado, V., Schofer, N., Eschenbach, L., … Makkar, R. R. (2017). Transcatheter Mitral Valve Replacement for Degenerated Bioprosthetic Valves and Failed Annuloplasty Rings. Journal of the American College of Cardiology, 70(9), 1121–31. -
Unmasking of familial long QT syndrome type 2 with crystal methamphetamine exposure
Kumar, S., Sharma, R., & Kalman, J. M. (2014). Unmasking of familial long QT syndrome type 2 with crystal methamphetamine exposure. HEART RHYTHM, 11(10), 1836–38. -
Impact of Preprocedural B-Type Natriuretic Peptide Levels on the Outcomes After Transcatheter Aortic Valve Implantation
Abramowitz, Y., Chakravarty, T., Jilaihawi, H., Lee, C., Cox, J., Sharma, R. P., … Makkar, R. R. (2015). Impact of Preprocedural B-Type Natriuretic Peptide Levels on the Outcomes After Transcatheter Aortic Valve Implantation. AMERICAN JOURNAL OF CARDIOLOGY, 116(12), 1904–9.
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Outcomes in Patients With Transcatheter Aortic Valve Replacement and Left Main Stenting The TAVR- LM Registry
Chakravarty, T., Sharma, R., Abramowitz, Y., Kapadia, S., Latib, A., Jilaihawi, H., … Makkar, R. R. (2016). Outcomes in Patients With Transcatheter Aortic Valve Replacement and Left Main Stenting The TAVR- LM Registry. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 67(8), 951–60.
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Controversies in Out of Hospital Cardiac Arrest?
Sharma, R. P., & Stub, D. (2016). Controversies in Out of Hospital Cardiac Arrest? Interventional Cardiology Clinics, 5(4), 551–59.
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Effect of ascending aortic dimension on acute procedural success following self-expanding transcatheter aortic valve replacement A multicenter retrospective analysis
Maeno, Y., Yoon, S.-H., Abramowitz, Y., Watanabe, Y., Jilaihawi, H., Lin, M.-S., … Makkar, R. R. (2017). Effect of ascending aortic dimension on acute procedural success following self-expanding transcatheter aortic valve replacement A multicenter retrospective analysis. INTERNATIONAL JOURNAL OF CARDIOLOGY, 244, 100–105.
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Optimal sizing for SAPIEN 3 transcatheter aortic valve replacement in patients with or without left ventricular outflow tract calcification
Maeno, Y., Abramowitz, Y., Jilaihawi, H., Israr, S., Yoon, S., Sharma, R. P., … Makkar, R. R. (2017). Optimal sizing for SAPIEN 3 transcatheter aortic valve replacement in patients with or without left ventricular outflow tract calcification. EUROINTERVENTION, 12(18), E2177–E2185.
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Outcomes in Transcatheter Aortic Valve Replacement for Bicuspid Versus Tricuspid Aortic Valve Stenosis
Yoon, S.-H., Bleiziffer, S., De Backer, O., Delgado, V., Arai, T., Ziegelmueller, J., … Makkar, R. (2017). Outcomes in Transcatheter Aortic Valve Replacement for Bicuspid Versus Tricuspid Aortic Valve Stenosis. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 69(21), 2579–89.
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Advanced Imaging of Intracranial Atherosclerosis: Lessons from Interventional Cardiology
Pavlin-Premrl, D., Sharma, R., Campbell, B. C. V., Mocco, J., Opie, N. L., & Oxley, T. J. (2017). Advanced Imaging of Intracranial Atherosclerosis: Lessons from Interventional Cardiology. FRONTIERS IN NEUROLOGY, 8, 387.
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Relation Between Left Ventricular Outflow Tract Calcium and Mortality Following Transcatheter Aortic Valve Implantation
Maeno, Y., Abramowitz, Y., Yoon, S.-H., Israr, S., Jilaihawi, H., Watanabe, Y., … Makkar, R. R. (2017). Relation Between Left Ventricular Outflow Tract Calcium and Mortality Following Transcatheter Aortic Valve Implantation. AMERICAN JOURNAL OF CARDIOLOGY, 120(11), 2017–24.
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Clinical outcomes and prognostic factors of transcatheter aortic valve implantation in bicuspid aortic valve patients
Yoon, S.-H., Sharma, R., Chakravarty, T., Kawamori, H., Maeno, Y., Miyasaka, M., … Makkar, R. R. (2017). Clinical outcomes and prognostic factors of transcatheter aortic valve implantation in bicuspid aortic valve patients. ANNALS OF CARDIOTHORACIC SURGERY, 6(5), 463–72.
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The Fluid Mechanics of Transcatheter Heart Valve Leaflet Thrombosis in the Neosinus
Midha, P. A., Raghav, V., Sharma, R., Condado, J. F., Okafor, I. U., Rami, T., … Yoganathan, A. P. (2017). The Fluid Mechanics of Transcatheter Heart Valve Leaflet Thrombosis in the Neosinus. CIRCULATION, 136(17), 1598-+.
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Too little, too much or just right? Goldilocks revisited….
Sharma, R., & Henry, T. D. (2018). Too little, too much or just right? Goldilocks revisited…. Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions, 91(5), 840–41.
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Response by Sharma et al to Letter Regarding Article, "The Fluid Mechanics of Transcatheter Heart Valve Leaflet Thrombosis in the Neosinus".
Sharma, R., Midha, P. A., Babaliaros, V., Makkar, R. R., & Yoganathan, A. P. (2018). Response by Sharma et al to Letter Regarding Article, "The Fluid Mechanics of Transcatheter Heart Valve Leaflet Thrombosis in the Neosinus". Circulation, 137(19), 2094–95.
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Recurrent severe aortic stenosis after transfemoral transcatheter valve-in-valve-in-valve replacement
Ochiai, T., Yoon, S.-H., Sharma, R., Chakravarty, T., Nakamura, M., Cheng, W., & Makkar, R. (2018). Recurrent severe aortic stenosis after transfemoral transcatheter valve-in-valve-in-valve replacement. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 155(5), E141–E144.
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Transcatheter aortic valve replacement in bicuspid aortic valve stenosis: where do we stand?
Yoon, S.-H., Sharma, R., Chakravarty, T., Miyasaka, M., Ochiai, T., Nomura, T., … Makkar, R. (2018). Transcatheter aortic valve replacement in bicuspid aortic valve stenosis: where do we stand? JOURNAL OF CARDIOVASCULAR SURGERY, 59(3), 381–91.
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Impact of Body Mass Index on the Outcomes Following Transcatheter Aortic Valve Implantation
Abramowitz, Y., Chakravarty, T., Jilaihawi, H., Cox, J., Sharma, R. P., Mangat, G., … Makkar, R. R. (2016). Impact of Body Mass Index on the Outcomes Following Transcatheter Aortic Valve Implantation. CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS, 88(1), 127–34.
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Computed tomography characteristics of the aortic valve and the geometry of SAPIEN 3 transcatheter heart valve in patients with bicuspid aortic valve disease
Kawamori, H., Yoon, S.-H., Chakravarty, T., Maeno, Y., Kashif, M., Israr, S., … Makkar, R. R. (2018). Computed tomography characteristics of the aortic valve and the geometry of SAPIEN 3 transcatheter heart valve in patients with bicuspid aortic valve disease. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 19(12), 1408–18.
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Variation in the Timing of Percutaneous Coronary Intervention and Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement
Ochiai, T., Yoon, S.-H., Flint, N., Sharma, R., Patel, V., Chakravarty, T., … Makkar, R. (2019). Variation in the Timing of Percutaneous Coronary Intervention and Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 74(13), B670.
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Patching residual leaks following a MitraClip procedure
Kar, S., & Sharma, R. (2019). Patching residual leaks following a MitraClip procedure. EUROINTERVENTION, 15(6), E482–E483.
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Timing and Outcomes of Percutaneous Coronary Intervention in Patients Who Underwent Transcatheter Aortic Valve Implantation.
Ochiai, T., Yoon, S.-H. H., Flint, N., Sharma, R., Chakravarty, T., Kaewkes, D., … Makkar, R. (2020). Timing and Outcomes of Percutaneous Coronary Intervention in Patients Who Underwent Transcatheter Aortic Valve Implantation. The American Journal of Cardiology.
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Comparison of Valve Performance of the Intra-Annular Self-Expanding Portico (TM) Transcatheter Aortic Valve With Contemporary Supra-Annular Self-Expanding and Intra-Annular Balloon-Expandable Valves: Insights From the PORTICO IDE Trial
Makkar, R. R., Waksman, R., Groh, M., Russo, M. J., Hermiller, J., Worthley, S., … Fontana, G. P. (2020). Comparison of Valve Performance of the Intra-Annular Self-Expanding Portico (TM) Transcatheter Aortic Valve With Contemporary Supra-Annular Self-Expanding and Intra-Annular Balloon-Expandable Valves: Insights From the PORTICO IDE Trial. JACC-CARDIOVASCULAR INTERVENTIONS, 13(4), S46.
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