Stanford Hospital's physicians are faculty members at the Stanford School of
Medicine, where they are at the forefront of the research that
leads to ground-breaking treatments for patients. Stanford clinicians
are scientists who regularly contribute to major advancements in their
fields. The following research papers have been published by members
of Stanford's Heart Transplant Team.
Clinical research studies
Clinical research studies are designed to answer specific questions,
sometimes about a new drug or medical device's safety and
effectiveness. Research studies may be observational studies or
clinical trials. Observational studies are those in which information
is collected from patients in order to better understand specific
conditions (for example, what factors are associated with long-term
survival after a heart transplant?) or to develop new tests that can
detect rejection or other heart transplant complications in their
early stages. Clinical trials are research studies in which patients
are assigned, by chance, to a new medication or to placebo (typically
a pill or liquid that looks like the study medication but does not
have any medicines in it). Clinical trials are done to determine if
new treatments are safe and effective in preventing or treating heart
Clinical research studies are done in close collaboration with
scientists and physicians from many areas of expertise across Stanford
University. To ensure the highest ethical standards are maintained,
the Institutional Review Board (IRB) is responsible for oversight of
Please feel free to discuss these studies with any member of the
Heart Transplant team or contact the Heart Transplant Research Nurse
Coordinator, Helen Luikart, RN, MS, at 650-724-2883.
This unusual procedure, known as a "domino" transplant, occurs when one recipient receives a heart-lung transplant from a deceased donor, while the existing healthy heart of the heart-lung recipient is given to a second patient. The rare procedure has only been performed eight times at Stanford, last in 1994.
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.