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Amputation is an acquired condition that results in the loss of a limb, usually from injury, disease, or surgery. Congenital (present at birth) limb deficiency occurs when an infant is born without part or all of a limb. In the United States, 82 percent of amputations are due to vascular disease, 22 percent to trauma, 4 percent are congenital, and 4 percent are due to tumors. About 1.2 million individuals in the U.S. are living with an amputation, with 185,000 performed each year.