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The most common sign is an oddly shaped head at birth or by the time the child is a few months old. For example, the skull may become long and narrow. Or it may be very flat and broad in front or back or on the sides. The baby may have a misshapen nose or jaw.
An oddly shaped head may be the only sign of craniosynostosis.
In rare cases, the disease causes pressure to build up on the baby's brain. This can cause brain damage and can make the baby develop more slowly than other children.