For Cushing's disease (Cushing's syndrome due to a pituitary tumor), the treatment is surgical removal of the tumor, known as transsphenoidal surgery. Using a special microscope and very fine instruments, the surgeon approaches the pituitary gland through a nostril. Because this is an extremely delicate procedure, patients are often referred to centers specializing in this type of surgery.
The success, or cure, rate of transsphenoidal surgery procedure is over 80% when performed by a surgeon with extensive experience. If surgery fails, it can be repeated, often with good results. After curative pituitary surgery, cortisol levels may drop to very low levels. Patients are often given a synthetic form of cortisol (such as hydrocortisone or prednisone) as replacement therapy, which is usually stopped within the year.
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.