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One APC mutation in particular, called I1307K, is present in 6% of the Ashkenazi Jewish population. This mutation is associated with a 10-20% risk of colorectal cancer (slightly more than double the risk of someone else in the general population). However, people with this mutation do not present with the classic "carpet of polyps" in the colorectum seen in FAP.
The Stanford Medicine Online Second Opinion program offers you easy access to our world-class doctors. It’s all done remotely and you don’t have to visit our hospital or one of our clinics for this service. You don’t even need to leave home!