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Additional Symptoms of Hodgkin's Lymphoma Used in Staging
Hodgkin's lymphoma stages are also noted by the presence or absence of certain symptoms of the disease:
The letter "B" is added (i.e., stage IIB) is added if the person has any B symptoms (fever, night sweats, weight loss).
If a person does not have these B symptoms, the letter "A" is added after the Roman numeral.
If the Hodgkin's disease has spread from a lymph node to a nearby organ, the letter "E" is added.
If it involves the spleen, the letter "S" may be added.
The letter "X" may be added if a person has bulky disease. This means a tumor in the chest is at least one-third as wide as the chest, or a tumor in another area is at least 10 centimeters (about 4 inches) across. Bulky disease may require more intensive treatment.
For example, stage IIIB is disease that is symptomatic, involves lymph node regions or structures on both sides of the body, and is further classified depending on the organs and areas involved.
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