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Symptoms and Features Associated with Peutz-Jeghers Syndrome
Features Associated with Peutz-Jeghers Syndrome
The features associated with Peutz-Jeghers syndrome may include the following:
Melanocytic macules (dark blue or brown moles)
These moles may be located around and/or in the mouth (including the lips), and around the eyes, nostrils, and anus. Dark moles may also appear on the fingers. These lesions may fade by adulthood.
Multiple polyps in the gastrointestinal tract
Increased risk of benign (noncancerous) tumors of the ovaries and testes
Increased risk of stomach, esophageal, breast, colon, pancreatic, and ovarian cancers