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Symptoms of Recurrent Hypersomnia
Symptoms of Kleine-Levin Syndrome
Kleine-Levin syndrome is a rare sleep disorder that most commonly affects teens. People with this neurological disorder experience recurring periods of excessive sleep with behavioral changes. Onset of episodes is often abrupt, and sometimes preceded by flu-like symptoms. Episodes usually last 1-3 weeks. When an episode begins, the patient becomes drowsy and sleeps for most of the day and night, waking only to eat or use the bathroom. When awake but in episode, he or she frequently seems "out of it" and irritable. Childlike behaviors, sexual deshinibition, megaphagia may be observed. They also experience confusion, disorientation, and a complete lack of energy and emotion. People with recent onset KLS cannot attend school, work or care for themselves during episodes; most are bedridden, tired and uncommunicative. Offset of episodes is also often abrupt, and may be associated with a brief bout of insomnia.
Teenage boys account for most cases of KLS. In some instances, those suffering from KLS can go weeks, months or even years without displaying any symptoms, then have a sudden reoccurrence. The cause of KLS is still unknown, but the disorder generally resolves slowly over years. Episodes become less frequent and severe, to resolve in early adulthood.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.