Large-scale genetic changes such as loss or gain of chromosomes are important drivers of solid tumor carcinogenesis. Recent technological advances in genomic profiling have allowed quantitative detection of gene copy numbers, leading to identification of the 14q13.3 gene locus as functionally important in non-small cell lung cancers.
View details for DOI 10.1158/1078-0432.CCR-10-3081
View details for Web of Science ID 000287913200002
View details for PubMedID 21163872