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The Spectrum of Median Craniofacial Dysplasia PLASTIC AND RECONSTRUCTIVE SURGERY Allam, K. A., Wan, D. C., Kawamoto, H. K., Bradley, J. P., Sedano, H. O., Saied, S. 2011; 127 (2): 812-821

Abstract

Given the multiple permutations in craniofacial malformations, classification of median craniofacial dysplasia or midline Tessier no. 0 to 14 clefts has been difficult and disjointed. In this review, the authors present a summary of normal embryology, prior terminology, and their proposed new classification system. Median craniofacial dysplasia has tissue agenesis and holoprosencephaly at one end (the hypoplasias), frontonasal hyperplasia and excessive tissue (the hyperplasias) at the other end, and abnormal splitting or clefting and normal tissue volume (dysraphia) occupying the middle portion of the spectrum. These three distinct subclassifications have different forms of anomalies within their groups.

View details for DOI 10.1097/PRS.0b013e318200aa08

View details for Web of Science ID 000286928100040

View details for PubMedID 21285785