AUA Guideline for the Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome JOURNAL OF UROLOGY Hanno, P. M., Burks, D. A., Clemens, J. Q., Dmochowski, R. R., Erickson, D., Fitzgerald, M. P., Forrest, J. B., Gordon, B., Gray, M., Mayer, R. D., Newman, D., Nyberg, L., Payne, C. K., Wesselmann, U., Faraday, M. M. 2011; 185 (6): 2162-2170

Abstract

To provide a clinical framework for the diagnosis and treatment of interstitial cystitis/bladder pain syndrome.A systematic review of the literature using the MEDLINE® database (search dates 1/1/83-7/22/09) was conducted to identify peer reviewed publications relevant to the diagnosis and treatment of interstitial cystitis/bladder pain syndrome. Insufficient evidence-based data were retrieved regarding diagnosis and, therefore, this portion of the Guideline is based on Clinical Principles and Expert Opinion statements. The review yielded an evidence base of 86 treatment articles after application of inclusion/exclusion criteria. These publications were used to create the majority of the treatment portion of the Guideline. When sufficient evidence existed, the body of evidence for a particular treatment was assigned a strength rating of A (high), B (moderate) or C (low). Additional treatment information is provided as Clinical Principles and Expert Opinion when insufficient evidence existed. See text and algorithm for definitions, and detailed diagnostic management, and treatment frameworks.The evidence-based guideline statements are provided for diagnosis and overall management of interstitial cystitis/bladder pain syndrome as well as for various treatments. The panel identified first through sixth line treatments as well as developed guideline statements on treatments that should not be offered.Interstitial cystitis/bladder pain syndrome is best identified and managed through use of a logical algorithm such as is presented in this Guideline. In the algorithm the panel identifies an overall management strategy for the interstitial cystitis/bladder pain syndrome patient. Diagnosis and treatment methodologies can be expected to change as the evidence base grows in the future.

View details for DOI 10.1016/j.juro.2011.03.064

View details for Web of Science ID 000290389600044

View details for PubMedID 21497847