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Ganglioglioma arising from dysplastic cortex EPILEPSIA Ortiz-Gonzalez, X. R., Venneti, S., Biegel, J. A., Rorke-Adams, L. B., Porter, B. E. 2011; 52 (9): E106-E108

Abstract

We report the case of a child who presented at 3 months of age with complex partial seizures, a linear facial nevus, and magnetic resonance imaging (MRI) showing delayed myelination and thickened cortex in the left temporal, parietal, and occipital regions. A repeat 3Tesla MRI scan with and without contrast at 6 months again showed cortical dysplasia of the left hemisphere. No other abnormalities were seen. A third scan at 3 years 6 months showed a 2.5 cm, round, hyperintense lesion on both T(2) and T(1) sequences. The lesion and surrounding dysplastic cortex were resected. Palmini grade IIA dysplasia and a ganglioglioma were diagnosed. These findings suggest that cellular components of cortical dysplasias have oncogenic potential.

View details for DOI 10.1111/j.1528-1167.2011.03124.x

View details for Web of Science ID 000294973700002

View details for PubMedID 21668439