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Preanalytical Delay Reduces Sensitivity of QuantiFERON-TB Gold In-Tube Assay for Detection of Latent Tuberculosis Infection JOURNAL OF CLINICAL MICROBIOLOGY Doberne, D., Gaur, R. L., Banaei, N. 2011; 49 (8): 3061-3064

Abstract

The effects of incubation delays on the accuracy of the QuantiFERON-TB gold in-tube assay (QFT-GIT) were measured. Compared to immediate incubation, 6- and 12-hour delays resulted in positive-to-negative reversion rates of 19% (5/26) and 22% (5/23), respectively. These findings underscore the need for standardizing QFT-GIT preanalytical practices.

View details for DOI 10.1128/JCM.01136-11

View details for Web of Science ID 000293221900054

View details for PubMedID 21697332