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Biochemistry to the Rescue: A CIC-2 Auxiliary Subunit Provides a Tangible Link to Leukodystrophy NEURON Maduke, M. C., Reimer, R. J. 2012; 73 (5): 855-857
Abstract
ClC-2 is a broadly distributed chloride channel with an enigmatic neurophysiological function. In this issue of Neuron, Jeworutzki et al. (2012) use a biochemical approach to identify GlialCAM, a protein with a defined link to leukodystrophy, as a ClC-2 auxiliary subunit.
View details for DOI 10.1016/j.neuron.2012.02.012
View details for Web of Science ID 000301558600001
View details for PubMedID 22405196