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TREATMENT OF REFRACTORY ORBITAL PSEUDOTUMORS WITH PULSED CHEMOTHERAPY OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY PARIS, G. L., WALTUCH, G. F., Egbert, P. R. 1990; 6 (2): 96-101

Abstract

Five patients with orbital pseudotumor refractive to initial therapy are discussed. Three had a destructive granulomatous process associated with a sclerosing component. Two exhibited a predominantly lymphocytic infiltration. Chemotherapy with Prednisone (100 mg/day) and either Cytoxan (100 mg/day) or Chlorambucil (10 mg/day) in 5-day pulses is described. All patients responded clinically to this treatment without unfavorable side effects.

View details for PubMedID 2285671