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The phosphatase PP2A links glutamine to the tumor suppressor p53. Molecular cell Gwinn, D., Sweet-Cordero, E. A. 2013; 50 (2): 157-158
Abstract
In this issue of Molecular Cell, Reid et al. (2013) show that glutamine withdrawal causes PP2A-mediated activation of p53 through its regulator EDD, linking levels of a critical metabolite to an important regulator of cell survival and proliferation.
View details for DOI 10.1016/j.molcel.2013.04.010
View details for PubMedID 23622513