PROSTAGLANDIN SYNTHESIS IN HUMAN PLACENTA AND FETAL MEMBRANES PROSTAGLANDINS Duchesne, M. J., THALERDAO, H., DEPAULET, A. C. 1978; 15 (1): 19-42

Abstract

The conversion of exogenous arachidonic acid into prostaglandins was studied in human placenta and fetal membrane microsomes. Only one prostaglandin was formed, prostaglandin E2 (PGE2), in fetal membrane microsomes. In placental microsomes PGE2 was further transformed into 15 keto-PGE2. Cofactor requirements and some characteristics of the system were studied. 1 to 3% conversion of arachidonic acid into prostaglandins was observed in placental microsomes and 5 to 8% conversion in fetal membrane microsomes.

View details for Web of Science ID A1978EL87500003

View details for PubMedID 24235