A HUMAN MONOCLONAL-ANTIBODY TO RHG VOX SANGUINIS Foung, S. K., Blunt, J., Perkins, S., WINN, L., GRUMET, F. C. 1986; 50 (3): 160-163

Abstract

Hybridomas secreting a human monoclonal IgG1 antibody against a variant of the rhG antigen were produced from B lymphocytes of an Rh-negative donor with serum antibodies to D and G [correction of C] antigens. The antibody reacts by indirect hemagglutination with nearly all C- or D-positive cells, confirming the strong association in the expression of G with D or C antigens. The lack of antibody reactivity to C-negative Du cells suggests a particular epitope on the D complex associated with the G antigen.

View details for Web of Science ID A1986A969300008

View details for PubMedID 2424176