COMPARISON OF HOST-CELL INFILTRATES IN PATIENTS WITH FOLLICULAR LYMPHOMA WITH AND WITHOUT SPONTANEOUS REGRESSION AMERICAN JOURNAL OF CLINICAL PATHOLOGY Strickler, J. G., COPENHAVER, C. M., ROJAS, V. A., Horning, S. J., Warnke, R. A. 1988; 90 (3): 257-261

Abstract

The "host cell infiltrates" in five patients with low-grade follicular lymphoma who had spontaneous regression without therapy were studied with the use of immunohistochemical methods applied to frozen sections. These infiltrates were compared with the "host cell infiltrates" in six patients with follicular lymphoma with progressive disease. The group with progressive disease was selected to be similar to the group with spontaneous regression in age, sex, histologic characteristics, and stage of disease. The patients with spontaneous regression had significantly more T-helper cells in the host cell infiltrate than the control patients. There were no statistically significant differences between the two groups in numbers of cytotoxic/suppressor T-cells, macrophages, Tac-positive cells, Leu-7-positive cells, or proliferating cells.

View details for Web of Science ID A1988P904100005

View details for PubMedID 2970792