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HEPATOCELLULAR-CARCINOMA IN CHINESE MALES AND FEMALES - POSSIBLE CAUSES FOR THE MALE PREDOMINANCE CANCER Lai, C. L., Gregory, P. B., Wu, P. C., Lok, A. S., Wong, K. P., Ng, M. M. 1987; 60 (5): 1107-1110

Abstract

The male-female ratio in 186 hepatocellular carcinoma (HCC) Chinese patients was 5:1. The clinical presentation, biochemical parameters, and histologic findings were the same in both sexes except for a higher proportion of underlying cirrhosis (P = 0.02), and spider naevi (P = 0.04) in the men. There were also more smokers and alcohol drinkers among the men. Over 75% of both sexes were positive for the hepatitis B surface antigen. The possible contributory factors to the predominance of males to females in HCC included: the association with the hepatitis B virus, the higher proportion of male cirrhotics, smoking, and alcohol drinking. The survival probability for both sexes was equally poor; the median survival was 8 weeks for males and 10 weeks for females.

View details for Web of Science ID A1987J662600030

View details for PubMedID 3038298