ADENOCARCINOMA WITH NEUROENDOCRINE DIFFERENTIATION OF THE URINARY-BLADDER - CLINICOPATHOLOGICAL, IMMUNOHISTOCHEMICAL, AND ULTRASTRUCTURAL-STUDY ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE ABENOZA, P., MANIVEL, C., Sibley, R. K. 1986; 110 (11): 1062-1066

Abstract

We describe a primary mixed adenocarcinoma-neuroendocrine carcinoma of the urinary bladder of probable urachal origin. Neuroendocrine differentiation was confirmed by ultrastructural (neurosecretory granules) and immunohistochemical studies (chromogranin and neuron-specific enolase). Two local recurrences and multiple metastases consisted exclusively of the neuroendocrine component. The patient died 30 months after diagnosis with widely metastatic neuroendocrine carcinoma.

View details for Web of Science ID A1986E615300019

View details for PubMedID 3778122