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ALPHA-INTERFERON ADMINISTRATION IN CYTOMEGALOVIRUS RETINITIS ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Chou, S., Dylewski, J. S., Gaynon, M. W., Egbert, P. R., Merigan, T. C. 1984; 25 (1): 25-28

Abstract

Four patients, including three with the acquired immunodeficiency syndrome (AIDS), were treated with high-dose, buffy coat-derived alpha-interferon for progressive cytomegalovirus retinitis. Two of these patients had decreased viruria during therapy and the other two had increased viruria. There was evidence of progression of disease despite therapy in all patients, although the retinitis eventually became quiescent in the patient without AIDS. The severe immunosuppression encountered in AIDS patients complicates the management of cytomegalovirus and other opportunistic infections.

View details for Web of Science ID A1984RY30400007

View details for PubMedID 6322678

View details for PubMedCentralID PMC185427