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RED-BLOOD-CELL SIZE AND GLYCOLYTIC ENZYME-ACTIVITY - RELATIONSHIP TO NUMBER OF INTRA-MEDULLARY CELL DIVISIONS PEDIATRIC RESEARCH Glader, B. E., McCrimmons, D., MULLERSOYANO, A., Platt, O. 1978; 12 (4): 308-309

Abstract

In order to assess how the number of cell divisions influences the red blood cell (RBC) content of proteins other than hemoglobin, we measured the activity of two age-independent glycolytic enzymes in macrocytic, normal, and microcytic RBCs. The enzymes measured were phosphoglycerate kinase (PGK) and lactic dehydrogenase (LDH). In macrocytes, both PGK and LDH activity/10(10) RBCs were increased 1.6-fold over normal RBCs. In microcytes, however, the activity of these enzymes was identical to that seen in normal RBCs.

View details for Web of Science ID A1978EV11400012

View details for PubMedID 652413