INTRAVENOUS MIDAZOLAM DOES NOT CHANGE LOWER ESOPHAGEAL SPHINCTER PRESSURE SOUTH AFRICAN MEDICAL JOURNAL Rubin, J., BROCKUTNE, J. G., Downing, J. W. 1983; 64 (26): 1024-1025

Abstract

The effect of intravenous midazolam 0.3 mg/kg on lower oesophageal sphincter (LOS) pressure was studied in 8 healthy volunteers. No effect on LOS pressure was noted. The importance of this finding in relation to the possible danger of gastro-oesophageal reflux and pulmonary aspiration of gastric acid content during induction of general anaesthesia is discussed.

View details for Web of Science ID A1983RV67600014

View details for PubMedID 6648742