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EFFECT OF METOCLOPRAMIDE ON LOWER ESOPHAGEAL SPHINCTER IN LATE PREGNANCY ANAESTHESIA AND INTENSIVE CARE BROCKUTNE, J. G., DOW, T. G., Welman, S., DIMOPOULOS, G. E., MOSHAL, M. G. 1978; 6 (1): 26-29

Abstract

The effects of intravenous metoclopramide (Maxolon) on the lower oesophageal sphincter (LOS) were studied in three groups of patients, one group being normal control and the other two being pregnant females, one without heartburn and the other with. Metoclopramide increases the LOS pressure 20.5, 15.2 and 10.2 cm H2O respectively (p less than 0.005, p less than 0.005 and p less than 0.05). These findings suggest that for patients undergoing elective or emergency obstetrical anaesthesia, intravenous metoclopramide may help reduce the incidence of regurgitation of gastric contents.

View details for Web of Science ID A1978EV44700003

View details for PubMedID 665973