HIGH-DOSE METHOTREXATE IN OSTEOGENIC-SARCOMA ADJUVANT CHEMOTHERAPY AND LIMB SALVAGE RESULTS CANCER TREATMENT REPORTS Jaffe, N., Goorin, A., Link, M., Watts, H., Frei, E., VAWTER, G., Fellows, K. E., Beardsley, G. P., Abelson, H. T. 1981; 65: 99-106

Abstract

This communication provides a description and update of the three adjuvant regimens utilized at the Sidney Farber Cancer Institute. The disease-free survivals are: Study I--42% at 4 years; Study II--58% at 3 years; and Study III--currently 78%. In the limb salvage experience, among the evaluable patients, 6 of 12 treated with preoperative chemotherapy are disease free (median 32 months) and 12 of 14 (86%) treated without preoperative chemotherapy are disease free (median 13 months).

View details for Web of Science ID A1981NC61200015

View details for PubMedID 6948612