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INTRAVENOUS KETAMINE ANESTHESIA FOR MAJOR ABDOMINAL-SURGERY - ASSESSMENT OF A TECHNIQUE AND INFLUENCE OF ATARACTIC DRUGS ON PSYCHOMIMETIC EFFECTS OF KETAMINE ANAESTHESIA AND INTENSIVE CARE HOULTON, P. J., Downing, J. W., BROCKUTNE, J. G. 1978; 6 (3): 222-225

Abstract

Eighty-two patients presenting for major abdominal surgery were divided into five groups, and received intravenous ketamine, muscle relaxation and controlled ventilation with oxygen-enriched air. For maintenance of anaesthesia patients were given a single intravenous dose of either droperidol 5 mg, diazepam 5 mg, promethazine 25 mg, flunitrazepam 0.5 mg or lorazepam 2 mg, followed by incremental doses of ketamine. Flunitrazepam and lorazepam were the adjuvants associated with the lowest incidence of dreaming and emergence phenomena; postanaesthetic sequelae occurred most frequently with both ketamine/diazepam and ketamine/droperidol anaesthesia. However, the differences between the five groups failed to reach statistical significance.

View details for Web of Science ID A1978FW59300007

View details for PubMedID 717770