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Infection and multiple sclerosis: a possible role for superantigens? Trends in microbiology Brocke, S., VEROMAA, T., Weissman, I. L., Gijbels, K., Steinman, L. 1994; 2 (7): 250-254

Abstract

The association of infection with autoimmune diseases is enigmatic, partly because cause and effect are difficult to establish in chronic diseases. Microorganisms might initiate multiple sclerosis and trigger relapses of disease. Superantigens might be involved in autoimmunity through the (re)activation of T cells, including autoreactive cells, expressing certain T cell receptor beta chain variable regions.

View details for PubMedID 8081652