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Non-invasive diagnosis of acute heart-or lung-transplant rejection using radiolabeled annexin V 41st Annual Meeting of the Society-of-Pediatric-Radiology Blankenberg, F. G., Strauss, H. W. SPRINGER. 1999: 299–305

Abstract

Apoptosis is a ubiquitous set of cellular processes by which superfluous or unwanted cells are eliminated in the body without harming adjacent healthy tissues. When apoptosis is inappropriate (too little or too much), a variety of human diseases can occur, including acute heart or lung transplant rejection.Our group has developed a new radiopharmaceutical, radiolabeled annexin V, which can image apoptosis.Here we briefly review the biomolecular basis of apoptosis and its role in acute rejection. We also describe the possible use of radiolabeled annexin V to screen children noninvasively for acute rejection following organ transplantation.

View details for Web of Science ID 000080165700001

View details for PubMedID 10382201