CORONARY-ARTERY SPASM IN THE DENERVATED TRANSPLANTED HUMAN-HEART - A CLUE TO UNDERLYING MECHANISMS AMERICAN JOURNAL OF MEDICINE Buda, A. J., Fowles, R. E., Schroeder, J. S., Hunt, S. A., Cipriano, P. R., Stinson, E. B., HARRISON, D. C. 1981; 70 (5): 1144-1149

Abstract

The mechanism of coronary artery spasm has been poorly understood but there has been some suggestion that cardiac autonomic innervation may play an important role. We report coronary artery spasm in a 43 year old man two years after he had received a transplant. Provocative pharmacologic testing suggested functional denervation of the patient's heart. Thus, coronary artery spasm can occur in the transplanted, denervated human heart. Autonomic innervation of the heart is not essential in all cases of coronary spasm, and circulating catecholamines and/or metabolic of hormonal products may play an important role.

View details for Web of Science ID A1981LP92100027

View details for PubMedID 7015853