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Mass fabrication and delivery of 3D multilayer µTags into living cells. Scientific reports Chen, L. Y., Parizi, K. B., Kosuge, H., Milaninia, K. M., McConnell, M. V., Wong, H. P., Poon, A. S. 2013; 3: 2295-?

Abstract

Continuous monitoring of in vivo biological processes and their evolution at the cellular level would enable major advances in our understanding of biology and disease. As a stepping stone towards chronic cellular monitoring, we demonstrate massively parallel fabrication and delivery of 3D multilayer micro-Tags (µTags) into living cells. Both 10 µm × 10 µm × 1.5 µm and 18 µm × 7 µm × 1.5 µm devices containing inductive and capacitive structures were designed and fabricated as potential passive radio-frequency identification tags. We show cellular internalization and persistence of µTags over a 5-day period. Our results represent a promising advance in technologies for studying biology and disease at the cellular level.

View details for DOI 10.1038/srep02295

View details for PubMedID 23887586