Acquired epidermodysplasia verruciformis JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Rogers, H. D., MacGregor, J. L., Nord, K. M., Tyring, S., Rady, P., Engler, D. E., Grossman, M. E. 2009; 60 (2): 315-320

Abstract

Epidermodysplasia verruciformis (EV) is a rare autosomal recessive genodermatosis with an increased susceptibility to specific human papillomavirus (HPV) genotypes. Classically, this viral infection leads to the development of tinea versicolor-like macules on the trunk, neck, arms, and face during childhood, and over time, these lesions can progress to squamous cell carcinoma. More recently, an EV-like syndrome has been described in patients with impaired cell-mediated immunity. We describe two cases of EV-like syndrome in HIV-positive patients, review all previously reported cases of EV in patients with impaired cell-mediated immunity, introduce the term "acquired epidermodysplasia verruciformis" to describe EV developing in the immunocompromised host and examine the limited treatment options for these patients.

View details for DOI 10.1016/j.jaad.2008.08.035

View details for Web of Science ID 000262617700019

View details for PubMedID 19150275