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Pyoderma Gangrenosum-like Lesions in Leukocyte Adhesion Deficiency I Treated with Intravenous Immunoglobulin PEDIATRIC DERMATOLOGY Nord, K. M., Pappert, A. S., Grossman, M. E. 2011; 28 (2): 156-161

Abstract

A 31-year-old Caucasian male with leukocyte adhesion deficiency I and a 20-year history of recurrent, painful cutaneous ulcerations on the extremities presented with fatigue and worsening pain in both legs. He had experienced minimal improvement in his leg ulcers from treatment with systemic steroids, numerous courses of systemic antibiotics, and brief trials of infliximab and mycophenolate mofetil. He was treated with monthly intravenous immunoglobulin infusions. Upon completion of six courses of intravenous immunoglobulin his ulcerations had nearly healed for the first time in a decade.

View details for DOI 10.1111/j.1525-1470.2010.01123.x

View details for Web of Science ID 000290381900013

View details for PubMedID 21366684