HYPERCALCEMIA AND VITAMIN-D METABOLISM IN HODGKINS-DISEASE - IS THERE AN UNDERLYING IMMUNOREGULATORY RELATIONSHIP CANCER Rieke, J. W., Donaldson, S. S., Horning, S. J. 1989; 63 (9): 1700-1707

Abstract

Hypercalcemia is not common in Hodgkin's disease, but in reported cases is often unassociated with bone involvement. A case is presented demonstrating a mechanism involving elevated levels of 1,25-dihydroxy vitamin D3 (calcitriol). Similar cases in the literature are reviewed. Data implicating calcitriol as a hematolymphoid regulatory hormone are discussed as they may relate to lymphomas, leukemias, and paraneoplastic lymphocyte and monocyte/macrophage activity.

View details for Web of Science ID A1989U165800009

View details for PubMedID 2649225