Heart and combined heart-kidney transplantation in patients with concomitant renal insufficiency and end-stage heart failure. American journal of transplantation SCHAFFER, J. M., Chiu, P., Singh, S. K., Oyer, P. E., Reitz, B. A., Mallidi, H. R. 2014; 14 (2): 384-396

Abstract

In patients with end-stage heart failure (ESHF) who are candidates for isolated heart transplant (HRT), dialysis dependence (DD) is considered an indication for combined heart-kidney transplantation (HKT). HKT remains controversial in ESHF transplant candidates with nondialysis-dependent renal insufficiency (NDDRI). Using United Network for Organ Sharing data, we examined the cumulative incidences of transplant and mortality in patients with DD and NDDRI waitlisted for HKT or HRT. In all groups, 3-month waitlist mortality was dismal: 31% and 21% for HRT- and HKT-listed patients with DD and 12% and 7% for HRT- and HKT-listed patients with NDDRI. Five-year posttransplant survival was improved in HKT recipients compared with HRT recipients for both patients with DD (73% vs. 51%, p?

View details for DOI 10.1111/ajt.12522

View details for PubMedID 24279876