Progressive multifocal leukoencephalopathy in pediatric patients: case report and literature review. Pediatric infectious disease journal Schwenk, H., Ramirez-Avila, L., Sheu, S., Wuthrich, C., Waugh, J., Was, A., DeGirolami, U., Burchett, S., Koralnik, I. J., Ahmed, A. 2014; 33 (4): e99-105

Abstract

Progressive multifocal leukoencephalopathy is a rare, demyelinating disease of the central nervous system caused by JC virus. Fewer than 30 cases have been reported in HIV- and non-infected children. We report the case of a 15-year-old girl with progressive multifocal leukoencephalopathy and AIDS who presented with nystagmus, dysarthria and ataxia. Following combined antiretroviral therapy, she developed immune reconstitution inflammatory syndrome, which proved fatal.

View details for DOI 10.1097/INF.0000000000000237

View details for PubMedID 24632669