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RNA switch at enhancers. Nature genetics Quinn, J. J., Chang, H. Y. 2014; 46 (9): 929-931
Abstract
Polycomb/Trithorax response elements (PRE/TREs) are genetic elements that can stably silence or activate genes. A new study describes how long noncoding RNAs (lncRNAs) transcribed from opposite strands of the Drosophila melanogaster vestigial PRE/TRE throw the switch between these two opposing epigenetic states.
View details for DOI 10.1038/ng.3074
View details for PubMedID 25162802