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Medical Advances in the Treatment of Postpartum Hemorrhage ANESTHESIA AND ANALGESIA Ducloy-Bouthors, A., Susen, S., Wong, C. A., Butwick, A., Vallet, B., Lockhart, E. 2014; 119 (5): 1140-1147

Abstract

Postpartum hemorrhage (PPH) is a leading cause of maternal mortality worldwide. Recent advances in the management of severe bleeding for trauma patients may provide insight into PPH management, but must be applied with caution considering the significant differences between trauma and obstetric patients. In this review, we summarized evidence for current management strategies for patients with major obstetric hemorrhage, including (1) rapid laboratory assessment of coagulopathy, (2) early transfusion of plasma and high plasma-to-red blood cell transfusion ratios in massive PPH, and (3) use of tranexamic acid and fibrinogen concentrates in the setting of PPH complicated by coagulopathy.

View details for DOI 10.1213/ANE.0000000000000450

View details for Web of Science ID 000343633500022

View details for PubMedID 25329026