Molecular imaging of PET reporter gene expression. Handbook of experimental pharmacology Min, J., Gambhir, S. S. 2008: 277-303

Abstract

Multimodality molecular imaging continues to rapidly expand and is impacting many areas of biomedical research as well as patient management. Reporter-gene assays have emerged as a very general strategy for indirectly monitoring various intracellular events. Furthermore, reporter genes are being used to monitor gene/cell therapies, including the location(s), time variation, and magnitude of gene expression. This chapter reviews reporter gene technology and its major pre-clinical and clinical applications to date. The future appears quite promising for the continued expansion of the use of reporter genes in many evolving biomedically related arenas.

View details for DOI 10.1007/978-3-540-77496-9_12

View details for PubMedID 18626607