Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
 

Learn about the flu shot, COVID-19 vaccine, and our masking policy »

Stanford Health Care

Bladder Cancer Screening in Aluminum Smelter Workers JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE Taiwo, O. A., Slade, M. D., Cantley, L. F., Tessier-Sherman, B., Galusha, D., Kirsche, S. R., Donoghue, A. M., Cullen, M. R. 2015; 57 (4): 421-427

Abstract

To present results of a bladder cancer screening program conducted in 18 aluminum smelters in the United States from January 2000 to December 2010.Data were collected on a cohort of workers with a history of working in coal tar pitch volatile exposed areas including urine analysis for conventional cytology and ImmunoCyt/uCyt+ assay.ImmunoCyt/uCyt+ and cytology in combination showed a sensitivity of 62.30%, a specificity of 92.60%, a negative predictive value of 99.90%, and a positive predictive value of 2.96%. Fourteen cases of bladder cancer were detected, and the standardized incidence ratio of bladder cancer was 1.18 (95% confidence interval, 0.65 to 1.99). Individuals who tested positive on either test who were later determined to be cancer free had undergone expensive and invasive tests.Evidence to support continued surveillance of this cohort has not been demonstrated.

View details for DOI 10.1097/JOM.0000000000000377

View details for Web of Science ID 000352507700016

View details for PubMedID 25525927