Internal carotid artery surgical revascularization in a pediatric patient with Schimke immuno-osseous dysplasia JOURNAL OF NEUROSURGERY-PEDIATRICS Westbroek, E. M., Mukerji, N., Kalanithi, P., Steinberg, G. K. 2015; 15 (2): 189-191

Abstract

Schimke immuno-osseous dysplasia (SIOD) is a rare autosomal recessive disorder characterized by spondyloepiphyseal dysplasia, episodic lymphopenia, renal failure, and cerebrovascular disease secondary to arteriosclerosis and myointimal hyperplasia. In this paper the authors report the first known application of internal carotid artery (ICA) surgical revascularization to relieve a high-grade focal stenosis of the ICA in a pediatric patient, a 6-year-old boy with SIOD. The clinical presentation, imaging features, operative technique, and postoperative course are described and the molecular genetics, pathophysiology, and treatment considerations in SIOD are discussed.

View details for DOI 10.3171/2014.10.PEDS14141

View details for Web of Science ID 000348409100009

View details for PubMedID 25431900