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Erdheim-Chester disease: case report with unique postmortem magnetic resonance imaging, high-resolution radiography, and pathologic correlation CLINICAL IMAGING de Abreu, M. R., Castro, M. O., Chung, C., Trudell, D., Biswal, S., Wesselly, M., Resnick, D. 2009; 33 (2): 150-153

Abstract

Erdheim-Chester disease is an infiltrative form of histiocytosis characterized by replacement of normal tissues by lipid-laden histiocytes. The disease typically infiltrates the medullary portion of the diaphysis and metaphysis of long bones, producing a characteristic radiological pattern dominated by bone sclerosis. It usually affects adults of 40 years of age with a clinical spectrum ranging from an asymptomatic focal bone lesion to multisystemic disease. This case report documents unique imaging and pathologic findings of Erdheim-Chester disease using close postmortem pathologic-imaging correlation.

View details for DOI 10.1016/j.clinimag.2008.09.009

View details for Web of Science ID 000264016200014

View details for PubMedID 19237062