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Long-term follow-up studies after homograft replacement of the mitral valve. Canadian Medical Association journal Graham, A. F., Schroeder, J. S., Daily, P. O., HARRISON, D. C. 1972; 107 (6): 516-519

Abstract

Follow-up studies on 132 patients who have received fresh aortic homograft replacement of the mitral valve since May 1967 indicate good long-term function of the valve. Clinically the majority of patients are greatly improved and are free from the risks of long-term anticoagulant therapy. Hemodynamic studies performed on 13 patients at 25 to 41 months postoperatively showed a significant decrease in left atrial and pulmonary artery pressures with a small increase in cardiac output. Late deterioration of the homograft produced severe insufficiency in four cases and organic stenosis in two cases. Reasons for isolated deterioration are suggested.

View details for PubMedID 5057008