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Abstract
Genome editing is the process of precisely modifying the nucleotide sequence of the genome. It has provided a powerful approach to research questions but, with the development of a new set of tools, it is now possible to achieve frequencies of genome editing that are high enough to be useful therapeutically. Genome editing is being developed to treat not only monogenic diseases but also infectious diseases and diseases that have both a genetic and an environmental component.
View details for DOI 10.1186/s13059-015-0859-y
View details for Web of Science ID 000366898900002
View details for PubMedID 26694713
View details for PubMedCentralID PMC4699361