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DEMODICIDOSIS IN CHILDHOOD ACUTE LYMPHOBLASTIC-LEUKEMIA - AN OPPORTUNISTIC INFECTION OCCURRING WITH IMMUNOSUPPRESSION JOURNAL OF PEDIATRICS Ivy, S. P., Mackall, C. L., Gore, L., Gress, R. E., Hartley, A. 1995; 127 (5): 751-754

Abstract

We report demodicidosis in 11 children with acute lymphoblastic leukemia and a mildly pruritic, erythematous papular dermatitis that developed in areas rich in sebaceous glands. Dermodex eruptions were safely and effectively treated with 5% permethrin. Proliferation of commensal parasites of the skin, Dermodex folliculorum and Dermodex brevis may be an opportunistic infection of the skin in the immunocompromised host; the expected abrogation of cell-mediated immunity secondary to lymphocyte depletion predisposes some children given chemotherapy for leukemia to mite proliferation.

View details for Web of Science ID A1995TD93100017

View details for PubMedID 7472831