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Molecular approaches to understanding organogenesis. Seminars in pediatric surgery Crisera, C. A., Longaker, M. T., Gittes, G. K. 1999; 8 (3): 109-118

Abstract

The elucidation of the molecular mechanisms of mammalian organogenesis is the foundation on which we can build an improved understanding of organ pathology and pathophysiology. This paper uses the lung and the pancreas as paradigms to demonstrate how advances in basic molecular developmental biology research has translated into new appreciation of, and even novel potential treatment strategies for, congenital anomalies and mature diseases of these organs.

View details for PubMedID 10461323