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Poor adherence and low persistency rates for hepatocellular carcinoma surveillance in patients with chronic hepatitis B. Medicine Wang, C., Chen, V., Vu, V., Le, A., Nguyen, L., Zhao, C., Wong, C. R., Nguyen, N., Li, J., Zhang, J., Trinh, H., Nguyen, M. H. 2016; 95 (35)

Abstract

Our goal was to examine rates and predictors for hepatocellular carcinoma (HCC) surveillance adherence and persistency, since studies of such adherence and persistency in patients with chronic hepatitis (CHB) are currently limited.Consecutive CHB patients (N?=?1329) monitored for =1 year at 4 US clinics from January 1996 to July 2013 were retrospectively studied. Surveillance adherence was evaluated based on the American Association for the Study of Liver Diseases guidelines. Kaplan-Meier method was used to analyze surveillance persistency of 510 patients who had initially fair adherence (having at least annual surveillance imaging with further follow-up).Mean age was 48, with the majority being male (58%), Asian (92%), foreign-born (95%), and medically insured (97%). Patients with cirrhosis and those seen at university liver clinics were more likely to have optimal HCC surveillance than those without cirrhosis and those seen at community clinics (38.4% vs 21.6%, P?<0.001 and 33.5% vs 14.4%, P?

View details for DOI 10.1097/MD.0000000000004744

View details for PubMedID 27583921