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Abstract
The goals of tolerance in patients with solid organ transplants are to eliminate the lifelong need for immunosuppressive (IS) drugs and to prevent graft loss due to rejection or drug toxicity. Tolerance with complete withdrawal of IS drugs has been achieved in recipients of HLA-matched and mismatched living donor kidney transplants in 3 medical centers using hematopoietic cell transplants to establish mixed or complete chimerism.
View details for DOI 10.1182/blood-2015-12-685107
View details for Web of Science ID 000373505600008
View details for PubMedID 26796362
View details for PubMedCentralID PMC4807420